1,721,047 research outputs found
Colloidal Swarms Can Settle Faster than Isolated Particles: Enhanced Sedimentation near Phase Separation
By experimenting on model colloids where depletion forces can be carefully tuned and quantified, we show that attractive interactions consistently "promote" particle settling, so much that the sedimentation velocity of a moderately concentrated dispersion can even exceed its single-particle value. At larger particle volume fraction φ, however, hydrodynamic hindrance eventually takes over. Hence, v(φ) actually displays a nonmonotonic trend that may threaten the stability of the settling front to thermal perturbations. Finally, by discussing a representative case, we show that these results are relevant to the investigation of protein association effects by ultracentrifugation
Compressive yield stress of depletion gels from stationary centrifugation profiles
We have investigated the stationary sedimentation profiles of colloidal gels obtained by an arrested phase-separation process driven by depletion forces, which have been compressed either by natural gravity or by a centrifugal acceleration ranging between 6g and 2300g. Our measurements show that the gel rheological properties display a drastic change when the gel particle volume fraction exceeds a value φc , which barely depends on the strength of the interparticle attractive forces that consolidate the network. In particular, the gel compressive yield stress , which increases as for , displays a diverging behaviour for , with an asymptotic value that is close to the random close packing value for hard spheres. The evidence we obtained suggests that basically coincides with the liquid (colloid-rich) branch of the metastable coexistence curve, rather than with the lower (and φ-dependent) values expected for an attractive glass line penetrating inside the coexistence region
Tardive dyskinesia and DRD2, DRD3, DRD4, 5-HT2A variants in schizophrenia: an association study with repeated assessment
Istoplasmosi cutanea in una paziente nigeriana con sindrome da immunodeficienza acquisita residente a Verona
Istoplasmosi cutanea in una paziente nigeriana con sindrome da immunodeficienza acquisita residente a Veron
Tardive dyskinesia and DRD2, DRD3, DRD4, 5-HT2A variants in schizophrenia: an association study with repeated assessment.
Pharmacokinetic exposure and virological efficacy of a reduced atazanavir dose.
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Progressive multifocal leukoencephalopathy in an HIV patient receiving successful long-term HAART
Progressive multifocal leukoencephalopathy (PML) has been traditionally associated to severe immunosuppression and described mainly in highly active antiretroviral therapy (HAART)-naïve patients with a low lymphocyte CD4+ count. In the last years, some cases of PML have been described in HIV patients with a higher CD4+ count shortly after initiation of HAART and in association with the immune reconstitution inflammatory syndrome (IRIS). We report on a rare case of PML, not IRIS associated, that occurred in a HIV-positive patient with a lymphocyte CD4+ count greater than 700/μl and with an undetectable HIV viral load resulting from a long-term HAART. We describe the pathological and the ultrastructural features of the brain lesion. This case confirms that a severe immunosuppression or an IRIS is not required for the development of PML in HIV positives. The diagnosis of PML should always be considered in patients with consistent neurological symptoms, even with a high lymphocyte CD4+ level and a full viral suppression resulting from a long-term HAART
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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