1,720,954 research outputs found
Fecal Calprotectin (FC) in newborn: predictive marker of gastrointestinal and/or allergic disease?
No full textFecal Calprotectin (FC) is a biomarker of intestinal inflammation
both in adults and in children. High FC concentration
in healthy term and preterm newborns are similar to those
found in children with treated IBD and elevated FC levels
at two months of age have been found in infants with atopic
dermatitis, cow’s milk intolerance, severe infantile colic and
gastro oesophageal reflux.
Aim. To evaluate if FC levels at birth and at one month
of age can relate to the development of gastrointestinal functional
(DFGI) and/or allergic disease.
Methods. Between December 2007 and January 2008 a
telephonic interview was done to parents of 109 children
(mean age: 2.5 years) healthy term newborn in which FC has
been measured both at birth and at one month of age [1]. A
modified version of the original paediatric questionnaire for
paediatric functional gastrointestinal disorders (QPGS) [2]
was used for this interview, with specific questions added
to address allergic disease. Statistical analysis were performed
using SPSS version 10.1 for Windows. Models of
statistical variance were used to assess associations between
variables.
Results. 89/109 (81.6%) of parents accepted to answer.
There were 11/89 (12.3%) children with diagnosed cow’s
milk protein allergy (group 1), 5/89 (5.9%) children with
atopic dermatitis (group 2), one case (1.1%) with diagnosis
of infant regurgitation according to Roma III criteria (group
3); 72/89 (80.7%) have no disease (group 4). FC levels did
not differ among different groups. 45/89 (50.5%) children
A82 Abstracts / Digestive and Liver Disease 40 (2008) A41–A118
have familiar history positive for gastrointestinal diseases
(group 5).
Conclusion. We have not found correlation between
high FC levels during the first month of age and subsequent
development of allergic or gastrointestinal disease.
High calprotectin levels during the first month may be
related to its cytokine-like activity, playing a pivotal role
in the physiologic development of the immune response
and the host defence mechanisms against fungal or bacterial
infection
Fecal calprotectin (FC) in newborns: is it a predictive marker of gastrointestinal and/or allergic disease?
No full textFecal calprotectin seems to provide a safe and non-invasive means of helping differentiate between patients with organic and non-organic intestinal disease. Aim of our study was to evaluate if FC levels at birth and at first month of age can be a predictive biomarker of organic or functional gastrointestinal disease (FGIDs) and/or allergic disease diagnosed in 2 years old children. Between December 2007 and January 2008 a telephonic interview has been proposed to the parents of 109 consecutive healthy children, in which FC was measured at birth two years before. For our study, a modified version of the original paediatric questionnaire on paediatric functional gastrointestinal disorders (QPGS) was used for the interview. Specific questions were added to detect allergic diseases. We didâ€TMnt find any statistically significant result between FC measured at birth and during first month of life in children with allergy or not. The interference of familiarity does not lead to a statistically significant change in the fecal calprotectin values during the first month of life
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
- …
