133 research outputs found
Inheritance of congenital myasthenia gravis in smooth fox terrier dogs
No full textThe phenotypes with respect to congenital myasthenia gravis of 132 Smooth Fox Terrier dogs from 25 matings were analysed. These included both prospective and retrospective matings. It was determined that congenital myasthenia gravis in this breed is inherited in an autosomal recessive manner with complete penetrance. The symbol mg is proposed for the gene for congenital myasthenia gravis in the smooth fox terrier. Attempts to maintain live affected dogs to adulthood were unsuccessful and it is concluded that this is a lethal trait..RE: 35 ref.; SC: ZA; CA; VE; BE; 0V; 7V; 0I; 0ASource type: Electronic(1) http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0022-1503&isbn=&volume=75&issue=3&spage=163&pages=163-166&date=1984&title=Journal%20of%20Heredity&atitle=Inheritance%20of%20congenital%20myasthenia%20gravis%20in%20smooth%20fox%20terrier%20dogs.&aulast=Miller&pid=%3Cauthor%3EMiller%2c%20L%20M%3bHegreberg%2c%20G%20A%3bPrieur%2c%20D%20J%3bHamilton%2c%20M%20J%3C%2Fauthor%3E%3CAN%3E19842246429%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3
Protein-losing nephropathy associated with Borrelia burgdorferi seropositvity in a soft-coated wheaten terrier: Response to therapy
No full textA soft-coated wheaten terrier was examined for lameness with subsequent identification of protein-losing nephropathy, hypoalbuminemia, hyperglobulinemia, and seroconversion to Borrelia burgdorferi. Following doxycycline therapy, the urine protein loss decreased significantly and serum albumin concentration remained close to or within the reference interval for over 3 years, contrary to the reported poor prognosis for renal disease associated with B. burgdorferi or protein-losing nephropathy of soft-coated wheaten terriers
Dockerising Terrier for The Open-Source IR Replicability Challenge
No full textReproducibility and replicability are key concepts in science, and
it is therefore important for information retrieval (IR) platforms
to aid in reproducing and replicating experiments. In this paper,
we describe the creation of a Docker container for Terrier within
the framework of the OSIRRC 2019 challenge, which allows typical
runs to be reproduced on TREC Test Collections such as Robust04,
GOV2, Core2018. In doing so, it is hoped that the produced Docker
image can be of aid to other (re)producing baseline experiments on
these test collections. Initiatives like OSIRRC are key in advancing
these key concepts in the IR area. By making not only the source
code available, but also the exact same environment and standardising inputs and outputs, it is possible to easily compare approaches
and thereby improve the quality of the research for Information
Retrieval
Histological characterization of dilated cardiomyopathy in the juvenile Toy Manchester Terrier
No full textDilated cardiomyopathy (DCM), the most common form of cardiomyopathy in the dog, most often occurs in certain breeds. The objective of this study was to describe a rapidly progressive form of DCM that has been recently recognized in juvenile Toy Manchester Terrier dogs (TMTs). The clinical history and gross findings were reviewed in a group of 14 TMTs, and histologic sections of heart were examined in 12 of those 14 TMTs with DCM. Histochemical and histomorphometric analyses were employed to compare the heart in TMTs affected by DCM with that of control dogs. TMTs ranged in age from 10 to 58.3 weeks, with males and females being equally affected. Affected TMT hearts contained foci of degeneration and loss of myofibers with fibrosis and mild lymphoplasmacytic infiltrates. Less prominent features included foci of acute myofiber degeneration and necrosis with or without intralesional mineralization and mild to moderate suppurative and lymphoplasmacytic infiltrates. Morphometric quantification demonstrated that the right ventricle was more severely affected (P=.05) than the left ventricle with variable involvement of the interventricular septum. Immunohistochemistry for canine parvovirus was negative in all heart samples. However, the absence of parvoviral antigen does not rule out a possible viral or autoimmune cause. The presence of these myocardial lesions among closely related dogs suggests a genetic contribution to this disease process in the TMT
Presence of a supernumerary root of the right mandibular second molar in a Staffordshire terrier: a case report
No full textAuthor contributions:
All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by MFR, JC, and CR. The first draft of the manuscript was written by JC and MFR, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.The presence of a supernumerary root is an uncommon dental condition in canine patients, referring to an extra root that forms in a tooth beyond the standard number of roots that are typically expected for that specific tooth. It is a developmental anomaly most commonly observed in large-breed dogs, often as an incidental finding. These supernumerary roots may result from a disruption of the Hertwig's epithelial root sheath, which is responsible for root formation. A 3-year-old Staffordshire terrier presented for a complete oral examination under general anesthesia. The initial intraoral radiographic examination revealed a suspected crown-root fracture of the right mandibular second molar tooth (410). A radiographic examination using the parallel technique, a supernumerary root was identified ruling out the suspected crown-root fracture of 410. The supernumerary root did not require treatment as it was not associated with any pathology or clinical signs. This case report highlights the importance of full-mouth intraoral radiography in the diagnosis of unusual dental conditions, such as supernumerary roots, whose presence may become clinically relevant especially if treatment of a particular tooth becomes necessary. Radiographic technique, positioning and interpretation are essential to avoid misdiagnosis and potential negative consequences for the patient as well as guiding the clinician in making appropriate treatment choices. To the best of the authors' knowledge, the presence of a supernumerary root in a mandibular second molar in a dog has not been previously reported in the veterinary dental literature.Depto. de FisiologíaFac. de VeterinariaTRUEpu
Perception of American Pit Bull Terriers
No full textabstract: Behavior traits were examined in an observed experiment with the presentation of an American Pit Bull Terrier. The experiment was conducted at two locations (Wal Mart, Pet Smart) with searching for behavior traits (positive, negative) with an American Pit Bull Terrier present. In contrast to the hypothesis, there was more positive behavior traits than negative behavior traits. Together, these findings suggest that the presentation of an American Pit Bull Terrier has a more positive outlook on the breed rather than negative. Similar studies should be conducted to change the legislation in regard of "Pit Bulls" that cause discrimination against the breed
Quadricuspid aortic valve and associated abnormalities in a dog
No full textAn 11-month-old, female Scottish terrier was presented with a history of a heart murmur. The electrocardiogram showed signs of left ventricular enlargement, and radiography confirmed generalized cardiomegaly. Echocardiography revealed four equally sized aortic valve cusps. A ventricular septal defect, with systolic left-to-right shunting, and aortic regurgitation into both ventricles were also present. The dog was free of clinical signs 1 year after diagnosis.PUBM: Print; JID: 0415027; ppublishSource type: Electronic(1
DRD2 is associated with fear in some dog breeds
No full textBehavioral problems occur frequently in dogs and represent a significant threat to dog welfare. Anxiety, phobias, and fears comprise most of the canine behavioral conditions. The identification of an association between specific behavioral phenotypes and genetic variants of candidate genes would be a valuable tool in selection for dogs less susceptible to anxiety and fear, which may improve animal welfare. The DRD2 gene encodes the dopamine receptor 2. In this study, we found 8 SNPs in the DRD2 gene of the Havanese, a breed that shows large variation in a behavioral phenotype that manifests itself as a tendency to react fearfully by withdrawing in social situations. Significant associations were detected between 2 SNPs in exon 2 of the DRD2 gene and increased social fear in Havanese dogs (n = 158), as evaluated through observation by an external evaluator (respective allelic odds ratio: 4.35, 4.07) and through owner questionnaires (respective allelic odds ratio: 1.96, 2.2). Because different types of fear-related behavioral disorders commonly co-occur, the SNPs in exon 2 were also investigated for possible association to noise reactivity in 5 breeds: Havanese (n = 121), collie (n = 94), Irish soft-coated wheaten terrier (n = 44), Nova Scotia duck tolling retriever (n = 33), and standard poodle (n = 29). Significant associations were detected between SNPs in exon 2 of the DRD2 gene and noise reactivity in the Irish soft-coated wheaten terrier (respective allelic odds ratio: 2.64, 2.88) and collie (allelic odds ratio: 3.03). The same SNP alleles were associated with the beneficial phenotypes in the 3 breeds
Copper toxicosis in the Bedlington terrier: a diagnostic dilemma
No full textPT: JSource type: Electronic(1
Experimental study of heat pump thermodynamic cycles using CO2 based mixtures - Methodology and first results
No full textInternational audienceThe aim of this work is to study heat pump cycles, using CO 2 based mixtures as working fluids. Since adding other chemicals to CO 2 moves the critical point and generally equilibrium lines, it is expected that lower operating pressures as well as higher global efficiencies may be reached. A simple stage pure CO 2 cycle is used as reference, with fixed external conditions. Two scenarios are considered: water is heated from 10 °C to 65 °C for Domestic Hot Water scenario and from 30 °C to 35 °C for Central Heating scenario. In both cases, water at the evaporator inlet is set at 7 °C to account for such outdoor temperature conditions. In order to understand the dynamic behaviour of thermodynamic cycles with mixtures, it is essential to measure the fluid circulating composition. To this end, we have developed a non intrusive method. Online optical flow cells allow the recording of infrared spectra by means of a Fourier Transform Infra Red spectrometer. A careful calibration is performed by measuring a statistically significant number of spectra for samples of known composition. Then, a statistical model is constructed to relate spectra to compositions. After calibration, compositions are obtained by recording the spectrum in few seconds, thus allowing for a dynamic analysis. This article will describe the experimental setup and the composition measurement techniques. Then a first account of results with pure CO 2 , and with the addition of propane or R-1234yf will be given
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