60 research outputs found

    Medici, passeggeri e migranti a bordo dei grandi transatlantici tra le due guerre mondiali

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    Launched in 1925 and remaining in service until 1960, the ocean liner Conte Biancamano was among the principal protagonists in the history of Italian maritime navigation during the first half of the twentieth century. Reconstructing the trajectory of this vessel affords a distinctive insight into several of the century’s most significant phases: the golden age of transoceanic travel, when it operated on the North and South American routes serving passengers across all classes; the Fascist period, during which it voyaged to East Africa, India, and China; the Second World War, when it was requisitioned for the transport of American military personnel; and the post-war years, when it became the first passenger ship to be refitted in Italy. Upon its decommissioning in 1960, the then National Museum of Science and Technology acquired the ship’s bridge, ballroom, and several cabins, which are now preserved in the Aeronaval Pavilion. The multiple lives of the Biancamanoare examined in this volume through the contributions of scholars from diverse disciplines—including maritime history, economic and industrial history, labour history, and museology—thus enriching research into the historical and social contexts of which this ocean liner constitutes both a material and symbolic testimony

    Spurious ferromagnetic remanence detected by hybrid magnetometer

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    Nuclear magnetic resonance detection in ultra-low-field regime enables the measurement of different components of a spurious remanence in the polymeric material constituting the sample container. A differential atomic magnetometer detects simultaneously the static field generated by the container and the time-dependent signal from the precessing nuclei. The nuclear precession responds with frequency shifts and decay rate variations to the container magnetization. Two components of the latter act independently on the atomic sensor and on the nuclear sample. A model of the measured signal allows a detailed interpretation on the basis of the interaction geometry. Published under license by AIP Publishing

    Resveratrol-poor Red Wines Modulate SIRT1 in Human Renal Cells

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    The cardioprotective and anti-aging effects of red wine phenols, especially resveratrol (RSV), are well known. One of the most interesting biological properties of RSV and other naturally occurring phenols is the regulation of the expression and activity of SIRT1 (silent mating type information regulation 2 homolog). In view of the role of SIRT1 in acute and chronic renal diseases, we decided to study the effects of RSV-poor red wines on the expression of SIRT1 and HIF-2α (hypoxia-inducible factor 2α) to be compared with a nanomolar concentration of RSV or malvidin in proximal tubular cells of human kidneys (PTEC). Survival signaling systems activation (extracellular signal-regulated kinases, ERK and AMP-activated protein kinase, AMPK) was also investigated in PTEC incubated with wines. PTEC cells were incubated in the presence of RSV-poor wines diluted 1:1,000 for 30′, 90′, 120′ and 24 h. Expression of SIRT1 and HIF-2α, and activation of ERK and AMPK were analyzed by Western Blot. The data obtained show that wine modulates the expression of anti-aging molecular systems even when RSV is present in very small amounts

    Wine, sirtuins and nephroprotection: not only resveratrol

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    Resveratrol (RSV), a red wine component, and red wine itself exert cardio- and nephroprotective effects by modulating the Nitric Oxide system (NO). It has been shown that one of the main actions resulting from NO modulation is sirtuin regulation, especially SIRT-1 regulation. Elucidating both upstream and downstream molecular mechanisms of the SIRT-1 pathway is an open field of investigation that can explain its role not only in long-term processes, such as aging, but also in short-term processes, such as protection against ischemic damage. Our hypothesis suggests the importance of investigating compounds that are routine dietary compo- nents and do not necessarily contain RSV. Their nephroprotective activity could involve not only eNOS-dependent, but also NO-dependent but eNOS-independent mechanisms, or other molecular alter- native signaling systems

    Real-Time non-invasive detection of hidden objects in parcels and packages with sub-THz systems

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    Terahertz technology exploits the so-called frequency gap between the infrared and microwaves, typically referred to as the frequency band from 100 GHz to 30 Terahertz. The use of techniques based on the Terahertz radiation has long been studied in fields such as astronomy and solid state physics. Being a non harmful radiation for human beings, the Terahertz radiation is very interesting for applications since it can be used without worrying for the safety of users and operators. Recent innovations in Terahertz technologies are bringing a wide variety of applications, from non-destructive evaluation, to homeland security, from quality control of food and agricultural products to the biomedical sector. We report about an implementation of a sub-Terahertz investigation setup based on commercial solutions. The system is currently being used for non-invasive detection of metals inside parcels and boxes in security applications and in vivo studies of water leaf contents in smart agriculture

    Le scuole di volo

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    A cento anni dalla sua esplosione, la prima guerra mondiale si staglia ancora nella memoria come un evento a noi contemporaneo, autentico spartiacque del nostro tempo. Fu una spaventosa catastrofe che cambiò il volto dell’Europa e del mondo. Nella guerra furono coinvolti paesi dei cinque continenti, centinaia di milioni di uomini e donne, combattenti e civili, adulti e bambini. Essa fu combattuta nelle trincee e nelle fabbriche, nei campi di internamento e di prigionia, nelle campagne e nelle città, nelle redazioni dei giornali e negli studi cinematograici, negli ospedali e nei manicomi. Fu la prima guerra globale e totale. Questo volume riprende – con l’aggiunta di saggi di approfondimento – il percorso della mostra allestita a Palazzo Blu nel 2015. Testi e immagini raccontano la guerra a partire dai segni che essa impresse su Pisa e il suo territorio, la sua popolazione, le sue istituzioni: il dibattito e gli scontri di piazza su neutralità o intervento, il ruolo dell’Università, del Comune e della Diocesi, la mobilitazione militare e civile, l’esperienza del fronte e della prigionia compiuta dai cittadini arruolati, lo sviluppo dei campi di volo, l’alusso di feriti e mutilati, l’accoglienza dei profughi, la propaganda e la vita quotidiana, il computo delle vittime e la celebrazione del lutto
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