13,086 research outputs found

    The role of Plasmodium falciparum var genes in malaria in pregnancy

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    Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified

    Rowe, S L, 415830

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/414514Surname: ROWE. Given Name(s) or Initials: S L. Military Service Number or Last Known Location: 415830. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 54135.233895 Item: [2016.0049.46775] "Rowe, S L, 415830

    Rowe, J L, 402207

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/414511Surname: ROWE. Given Name(s) or Initials: J L. Military Service Number or Last Known Location: 402207. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 56473.233889 Item: [2016.0049.46772] "Rowe, J L, 402207

    Introduction. Shakespeare: Overlapping Mediascapes in the Mind

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    Introduction to the issue 'Shakespeare in the Media. Old and New', Anglistica aion, 15.2, 2011, co-edited with co-author Katherine Rowe, discussing the place of Shakespeare in the media today and the 'state of the art' of Shakespeare studies on the topic

    Letter from Sanford Rowe and W. W. Bass to Carl Hayden

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    Letter from Sanford Rowe and W. W. Bass to Carl Hayden requesting a re-examination on the proposed park boundaries as they are disadvantageous to current land owners surrounding the canyon

    Rowe, L.

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    Diane L. Rowe interview for a Wright State University History Course

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    On February 13, 2003 Paul Downing interviewed Diane Rowe, a dental assistant in Oakwood, Ohio, for a class project dealing with oral histories and capturing the history of the Miami Valley. During the interview Diane discusses growing up in North Dayton, working in dentistry, and what it has been like to work in downtown Dayton versus a suburb like Oakwood

    [A large bird and curved lines decorating a calling card for Miss. F. O. Rowe]

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    Frank [Frances Rowe] ALS to George [Niles Bird], June 26, 1879. Smithfield, [Pa.], page 5. From a collection made up of correspondence, documents, ephemera, and other materials related to members of the Bird family of East Smithfield, Pennsylvania

    Letter, Rowe C. Holcomb to Margaret Ray Buchanan, March 19, 1952

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    In this letter, dated March 19, 1952, Rowe C. Holcomb, the pastor of Hazelhurst Baptist Church, writes to Margaret Ray Buchanan to let her know he has typed the funeral sermon he gave for her father, Emmett L. Ray, as best he could remember it. The sermon is included.https://scholarsjunction.msstate.edu/mss-james-franklin-buchanan/1041/thumbnail.jp
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