1,721,007 research outputs found

    PREOPERATIVE INTRA-ORAL ULTRASOUND IN THE EVALUATION OF EARLY ORAL SQUAMOUS CELL-CARCINOMA: PROSPECTIVE STUDY

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    Preoperative evaluation of depth of invasion can predict occult metastasis in cervical lymph nodes of OSCC patients and target patients who need neck dissection but there is no standard modality to determine this parameter preoperatively. The primary aim of this study was to evaluate the accuracy of a preoperative measurement of depth of invasion using Ultrasonography and correlate the values obtained with histologically determined DOI measurements. Specifically, we used a very small and thin Ultrasound probe, like a toothbrush, that help directly reach the oral lesions. We enrolled 32 biopsy proven primary T1/T2/T3 OSCC patients who underwent pre-operative intraoral ultrasound for the evaluation of the tumor diameter and depth of invasion. Ultrasound sensitivity, specificity and accuracy in the assessment of the infiltration of the lamina propria, the correlation between Ultrasound and histological depth of invasion and the correlation between diameter of the lesion and depth of invasion assessed with Ultrasound were evaluated. Ultrasound sensitivity and specificity in the assessment of the infiltration of the lamina propria were respectively 93.3% and 100%. A significant correlation was found between the measurement of US-obtained and histologically obtained depth of invasion (r = 0.907; p < .0001; 95% CI, 0.816 to 0.954). A medium correlation was found between diameter of the lesion and depth of invasion assessed with Ultrasound (r = 0.591; p < .0001; 95% CI, 0.306 to 0.779). According to our results, intraoral Ultrasound is very accurate in determining tumor depth of invasion in OSCC patients and represents a useful, cost-effective and promisig tool to insert in the diagnostic flow-chart of OSCC

    Photo-Biomodulation as a prevention and management modality of oral mucositis in patients undergoing allogeneic hematopoietic stem cell transplantation: clinical study

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    Aim: To observe the effectiveness of a Photo-Biomodulation (PBM) protocol as a prevention and management modality for Oral Mucositis (OM) in patients undergoing conditioning regimen for allogeneic Hematopoietic Stem Cell Transplantation (aHSCT). Introduction: OM is one of the major debilitating complications of aHSCT. PBM has been recommended as a prophylactic intervention for OM in patients undergoing aHSCT. The absence of a standardized protocol and technical parameters for prevention of OM is still the principal limit. Materials and Methods: Forty-nine patients undergoing aHSCT were included in this study and divided into three groups; Observational Group (OG): 9 patients (3 females and 6 males) were subjected to PBM five sessions a week when the OM was developed till the complete resolution. Preventive Group (PG): 20 patients (7 females and 13 males) were subjected to PBM five sessions a week starting at one day before the conditioning regimen till the 10th day after transplantation (D+10). Retrospective Control Group (CG): 20 patients (10 females and 10 males) were selected to compare the obtained results. At each session, the OM score, pain value, count of blood cells, and the morphine dosage were recorded. Results: The mean duration of OM in PG (4.7 days) was significantly lower than CG (15 days) (p<0.05). Only 40% of PG showed severe OM, while it was shown in 85% of the CG (p<0.05). OM was not developed in 8 patients of the PG (with grade 0). Conclusion: The study demonstrates that the preventive PBM protocol reduced the severity and duration of OM in patients undergoing aHSCT

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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