14,354 research outputs found
Gilt stuccoes of the italian baroque
No full textC. Colombo, L. Toniolo, S. Bruni, P. Fermo, A. Casoli, G. Palla, C. L. Bianchi, Gilt stuccoes of the italian baroque. Studies in Conservation, 43, 1998, 201-208
REGIOSELECTIVE ACYLATION OF 6-DEOXY-L-HEXOSIDES AND 6-DEOXY-D-HEXOSIDES THROUGH LIPASE-CATALYZED TRANSESTERIFICATION - ENHANCED REACTIVITY OF THE 4-OH FUNCTION IN THE L SERIES
No full textPorcine pancreatic, Candida cylindracea, and Pseudomonas fluorescens lipases, suspended in organic solvents, were used to regioselectively acylate methyl α-L- and α-D-rhamnopyranoside and methyl α-L- and α-D-fucopyranoside. While the D-sugars always gave the 2-butyrate as the main product, their L enantiomers showed a different regioselectivity; however, by proper selection of the enzyme, in the L series the rather unreactive 4-OH function could be preferentially acylated
Nella scatola nera della crisi : tattiche di adattamento e exit strategies dei giovani milanesi
No full text
Hypercoagulability during l‐asparaginase treatment: the effect of antithrombin III supplementation in vivo
No full textTo evaluate the occurrence of hypercoagulability during treatment with l‐asparaginase (l‐ase), thrombin‐antithrombin complex (TAT) and d‐dimer levels in plasma were serially measured in 15 consecutive adult patients with acute lymphoblastic leukaemia or lymphoblastic lymphoma who had recently completed a chemotherapy cycle with cytosine arabinoside and methotrexate. The first eight patients (group A) received i.v. l‐ase alone (20000 U/m2 on alternate days over 10 d); the last seven patients (group B) received, in addition to l‐ase, bolus injection of antithrombin concentrate (2000 U) on alternate days for a total of six administrations, beginning with the second l‐ase infusion. Increased levels of TAT (P<0·05) and d‐dimer (P<0·01) were observed prior to l‐ase, possibly related to inflammation and cytolysis secondary to previous chemotherapy. In patients treated with l‐ase alone, further elevation of TAT (P<0·05) and persistence of increased d‐dimer were observed, associated with marked reduction of the anticoagulant activities of protein C, protein S and antithrombin III. At variance, in patients receiving antithrombin III supplementation there was no increase of TAT and a normalization of d‐dimer levels occurred during l‐ase treatment. In these patients, mean plasma antithrombin III activity was maintained at levels higher than 70% of normal throughout the treatment. The rate of decline of fibrinogen, factor IX, protein C and protein S was unaffected by antithrombin III supplementation, indicating that hypercoagulability has little if any relevance for the reduction of coagulation factors and inhibitors induced by l‐ase treatment. The usefulness of antithrombin III concentrates in preventing thromboembolic complications in patients submitted to l‐ase treatment remains to be determined. Copyright © 1990, Wiley Blackwell. All rights reserve
Oligosaccharides Related to Tumor-Associate Antigens. Part 2. Conformational analysis of the trisaccharide α-L-Fucp-(1→2)-β-D-Galp-(1→3)-β-D-GalpNAc, epitope structure recognized by the MBr1 antibody
No full textThe conformational space of the trisaccharide α-L-Fuc-(1 → 2)-β-D-Gal-(1 → 3)-β-D-GalNAc-1-OPr (2) and of its component disaccharide moieties α-L-Fuc-(1 → 2)-β-D-Gal-1-OMe (3) and β-D-Gal-(1 → 3)-β-D-GalNAc-1-OPr (4) was investigated with the aid of molecular-mechanics energy minimizations and molecular-dynamics simulations. These calculations suggested the occurrence of two conformations for each compound characterized by different Φ and ψ glycosidic angles. However, 1H-NMR investigation of D2O solutions of 2-4 indicated a sure preference for one of the two conformers with a contribution of the other one ranging from negligible to low
Growth of sp-sp2 nanostructures in a carbon plasma
No full textThe growth of sp and sp2 nanostructures in a carbon plasma is simulated by tight-binding molecular dynamics. The simulations are arranged so as to mimic the cluster formation conditions typical of a pulsed microplasma cluster source which is used to grow nanostructured sp-sp2 carbon films [ L. Ravagnan et al. Phys. Rev. Lett. 98 216103 (2007)]. The formation of linear, ring, and fullerenelike objects in the carbon plasma is found to proceed through a very long multistep process. Therefore, tight-binding simulations of unprecedented duration have been performed by exploiting the disconnected topology of the simulated carbon plasma which made it possible to implement a computationally efficient divide-and-diagonalize procedure. Present simulations prove that topologically different structures can be formed in experiments, depending on the plasma temperature and density. A thorough characterization of the observed structures as well as their evolution (caused both by thermal annealing and by cluster ripening) is provided
Solution of Simple Reference Cases
No full textThis chapter presents the solution of simple reference cases of frame structures with the use of force method, displacement method or mixed method. The presented cases consider different loading condition (distributed loads, concentrated loads, thermal actions), different boundary conditions (rigid and/or elastic constraints), different geometrical configuration of frame and load (inclined rods, symmetrical and anti-symmetrical load and frame) and different mechanical behaviour of rods (elastic, axially deformable, infinitely rigid in bending)
Short Notes on Kinematic Analysis
No full textThis chapter presents a short overview on the main concepts related to the kinematic analysis of frame structures
Solution of Complex Frames
No full textThis chapter presents the solution of complex examples mixing the simple cases presented in the previous chapter. The worked examples are solved with the use of force method, displacement method and/or mixed method
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