1,720,986 research outputs found
Randomized study on the effects of different strategies of intermittent pneumatic compression for lower limb claudication
Full text linkRiassunto: Studio randomizzato sugli effetti delle differenti strategie della compressione pneumatica intermittente per il trattamento della claudicatio degli arti inferiori.
A. Berni, L. Tromba, L. Falvo, F. Tartaglia, M. Sgueglia, S. Blasi, P. Polichetti
Introduzione. Lo scopo di questo studio è di valutare l’efficacia di differenti strategie di compressione pneumatica intermittente (IPC) per il trattamento della claudicatio degli arti inferiori.
Metodi. Sono stati analizzati in prospettiva cinque gruppi di studio. Gruppo 1: 9 pz non sottoposti ad IPC; gruppo 2: sei pazienti sottoposti ad IPC per un’ora tre volte al giorno per quattro mesi; gruppo 3: sei pazienti sottoposti ad IPC per due ore una volta al giorno per quattro mesi; gruppo 4: sei pazienti sottoposti ad IPC per un’ora tre volte al giorno per due mesi; gruppo 5: sei pazienti sottoposti ad IPC per due ore una volta al giorno per due mesi.
Risultati. Tutti i pazienti hanno completato il programma di trattamento e hanno dichiarato una compliance del 33% nel gruppo 2, dell’83% nel gruppo 3, del 66% nel gruppo 4 e del 100% nel gruppo 5. Il picco di velocità sistolica del flusso dell’arteria poplitea è cresciuto oltre i valori base in particolare laddove la durata della terapia è stata di 4 mesi ( gruppo 2 : 85%,gruppo 3 :81% vs gruppo 4:76%;gruppo 5 : 73%). Questi effetti benefici si sono protratti per circa 14 mesi e sono svaniti dopo 14 mesi dalla fine del trattamento con IPC. La distanza assoluta di percorrenza senza claudicatio è cresciuta alla fine del trattamento oltre il 101% nel gruppo 2, del 94% nel gruppo 3, dell’86% nel gruppo 4 e dell’83% nel gruppo 5 ed inoltre è aumentata oltre il valore di base dopo 14 mesi dalla fine della terapia. Nessuna differenza è stata osservata se il trattamento IPC è stato fatto una o tre volte al giorno.
Conclusioni. La terapia compressiva pneumatica intermittente effettuata due volte al giorno per quattro mesi ha fornito risultati eccellenti con soddisfacente compliance. Tuttavia questi benefici effetti non sono durevoli e svaniscono a distanza di circa un anno dalla fine del trattamento
Trattamento dei carcinomi differenziati della tiroide “Localmente avanzati”. Nostra esperienza
No full textTREATMENT OF "LOCALLY ADVANCES" WELL-DIFFERENTIATED THYROID CARCINOMA.
No full textTreatment of "locally advanced" well-differentiated thyroid carcinomas.
Falvo L, Catania A, Grilli P, Di Matteo FM, De Antoni E.
SourceDepartment of Surgical Sciences, 3rd training program in General Surgery, University of Rome La Sapienza, Italy. [email protected]
Abstract
PURPOSE: To analyse thyroid carcinomas having an extrathyroid extension in order to identify the principal prognostic factors and outline an effective therapeutic strategy.
METHODS: We selected a sample of 160 patients suffering from locally advanced "well differentiated thyroid carcinoma (T4) who had undergone surgery at the Department of Surgery of University of Rome "La Sapienza". The sample was subdivided into three groups: T4, limited type I, and extensive type II, T4 microcarcinomas.
RESULTS: We obtained excellent results with the T4 microcarcinomas, above all in patients under the age of 45, with a 94.5% survival rate, compared with 88% in patients aged over 45. In the extensive type II T4 carcinoma we obtained a survival rate of 29.4% in patients aged over 45 years.
CONCLUSIONS: Age, combined with an aggressive histological variant (Sclerosing and tall-cell papillary carcinoma), is an important factor in prognosis. The radicality of surgical excision is considered an important prognostic factor, although the results reported in the literature are contradictory. Aggressive surgery can free from the disease a high percentage of patients over the age of 50 even with T4. We deem it fundamental to perform total thyroidectomy in all advanced cases of thyroid neoplasm and to extend neoplasm excision to the adjacent tissues, even involving justified surgical demolition.
PMID: 15283382 [PubMed - indexed for MEDLINE
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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