1,830 research outputs found
Fibrosi polmonare idiopatica
No full textThe pulmonary interstitial disease denominated Idiopathic Pulmonary Fibrosis (or Cryptogenetic Fibrosing Alveolitis) is a specific form of chronic interstial pneumonitis, mostly associated with hystologic features defining the Usual Interstitial Pneumonitis. Between the other Idiopathic Interstitial Pneumonites this is the first by frequency and also the one characterised by the worst prognosis. A generally lethal disease (except in the unfrequent cases where a gastroesophageal reflux can be recognized as a pathogenetic determinant) which shows a fast, evident, unexplained increase worldwide, more frequent in males and in presenile age although diffuse enough in the feminine gender as well as in different ages. Potential risks and pathogenetic factors are described; the numerous acute and chronic conditions needing a differential diagnosis (in particular the other forms of idiopathic interstitial pneumonitis) are examined; the symptoms, both clinical (particularly the Velcro-like crepitations) and instrumental, such as cellular and biochemical information obtained by the bronchoalveolar lavage, hystopathology obtained by lung biopsy but specially imaging coming from high resolution computerized tomography are described. The last features, to be substantially distinguished in "ground glass" and "honeycombing", lead to the interesting observation of a better response to the specific medical treatment (essentially corticosteroids associated or not with azathioprine or cyclophosphamide) in those patient (often positively responding to the therapy, in some way) who are characterized by prevalence of "ground glass" lung images, compared with the patients characterized by "honeycombing" images, who undergo a more rapidly lethal, prognosis. Other pharmacologic agents have been submitted to trials, namely colchicine, pirphenidone, interferon, anti-TNFalpha, bosentan, but the results are temporary or ambiguous; although a very recent observation with an antioxidant (NAC in relatively high doses) leads to some interesting new interpretations. Good enough, anthough obviously "numerically" limited, are the results of the lung transplantation, with several kinds of overall advantages, at least in the experience of our Hospital, for the monolateral transplant
Ecosostenibilità come scelta di vita
No full textAlcuni nuovi insediamenti possono essere definiti, a buon diritto, comunità. La pratica dell’ecosostenibilità, infatti, si sostanzia di comportamenti collettivi e condivisi, di attività comuni in cooperazione e, più in generale, di una fitta rete di relazioni solidali. Ai benefici di costruzioni a basso impatto, preferibilmente concepite secondo i dettami della bioarchitettura, questi quartieri affiancano i vantaggi di servizi avanzati spesso gestiti in cooperazione fra gli abitanti. La condivisione di spazi e obiettivi, e il reciproco controllo sociale, determinano un’incidenza di comportamenti virtuosi molto maggiore che negli altri insediamenti, nei quali si lamenta spesso l’effetto paradosso di Jevons (il paradosso di Jevons ammonisce che quando gli “effetti collaterali” di un’attività si riducono molto - che siano il costo o l’impatto ambientale - essa appare così a buon mercato da accrescersi in misura anche maggiore del risparmio unitario). La complessità funzionale è un’altra peculiarità di questi quartieri che replicano l’intreccio di funzioni tipico delle comunità di villaggio: i campi comuni, ad esempio, sono uno scenario frequente nei paesi dell’Europa centro-settentrionale, così come laboratori artigianali e altre attività produttive specifiche
Progettare nel sociale:la scelta degli obiettivi strategici
No full textLa legge 328/2000 attribuisce ai Comuni, anche attraverso la costituzione dei Piani di Zona, il compito di individuare gli strumenti locali che contribuiscano al riordino, al potenziamento e alla messa in rete di interventi e servizi.
Essi dovrebbero essere in grado di porre in essere un “processo sistematico attraverso il quale l’organizzazione definisce, costruendo il coinvolgimento dei soggetti chiave, le priorità che sono essenziali nella sua missione e rispondenti all’ambiente in cui opera” , ovvero i Comuni devono avviare un processo di progettazione strategica dei servizi, in cui sono coinvolti una pluralità di attori che a diversi livelli realizzano gli interventi sociali. Mediante le politiche di concertazione tra i vari soggetti, istituzionali e non, ai Comuni spetta il compito di individuare, ideare, programmare, costruire, realizzare e valutare l’insieme dei servizi, da avviare su un determinato territorio.
Tutto ciò richiede, da parte dei soggetti coinvolti, una capacità di individuazione e di lettura dei bisogni e dei vari modelli di servizi che devono essere implementati in uno stesso territorio ed in situazioni differenti
L’ insieme dei soggetti coinvolti, dunque, è costituito dagli attori del sistema territoriale che, mossi da specifici bisogni/esigenze, traducono in un progetto di cambiamento, teso alla soddisfazione degli stessi, il risultato delle attività di concertazione.
L’ideazione di un qualsiasi intervento, comunque, richiede l’esistenza di alcuni fattori che possiamo definire come pre-condizioni, difficilmente modificabili, per l’avvio di un qualsiasi cammino progettuale: il contesto di riferimento, il bisogno/motivazione e la presenza di attori/decisor
Effect of Water Sorption on the Mechanical Properties of a CNT-Based Epoxy Resin
No full textThis study aims to assess the impact of water absorption on the mechanical properties of CNTs-composite using dynamic mechanical analysis (DMA). Water absorption results in a decrease in mechanical properties, such as storage modulus and Tan δ, due to swelling and plasticization effects. Specifically, the presence of water in the matrix causes the Tan δ peak to broaden. Following an approach that considers the Tan δ peak as comprising multiple relaxation mechanisms activated at different temperatures, an average glass transition temperature reduction of 20 °C was observed, along with a decrease in “network homogeneity” from 0.95 to 0.62 as water absorption increased
Cessione di quote sociali e restituzione di un finanziamento soci da acquirente ad alienante "per interposta società": ancora problemi per i versamenti in conto futuro aumento capitale?
No full textIl provvedimento in commento affronta la complessa tematica della qualificazione, e della conseguente rimborsabilità, degli apporti qualificati come versamenti in conto futuro aumento di capitale, piuttosto che come finanziamenti. Muovendo dalla considerazione che un versamento di patrimonio, diversamente da un finanziamento soci, di norma, non attribuisce al socio un diritto di rimborso, la nota si sofferma, in particolare, sulla sorte di tale apporto nell’ipotesi di alienazione della partecipazione da parte dell’autore di un versamento in conto futuro aumento di capitale.
The decision in comment examines the complex issue of the qualification, and consequent repayability, of payments qualified as contributions on account of future capital increases, rather than as loans. Beginning with the consideration that a contribution of capital, unlike a shareholders’ loan, does not normally give the shareholder a right of repayment, the note focuses, in particular, on the treatment of such contribution in the event of the alienation of the participation by the author of a contribution for a future capital increase
Electrical Behavior of Nanocomposites Exposed to Water Sorption
No full textThe present study examines the electrical response of nanocomposites to water uptake. Specifically, an electrical signal was employed to detect the amount of water absorbed in a carbon nanotube-based epoxy composite. The investigation focused on changes in the electrical resistance of the composite with a filler content (0.1% by weight) near the electrical percolation threshold. Water penetration results in “non-Fickian” diffusion behavior due to the composite's viscoelastic nature and plasticization effects. The variation in time of the resistance change ratio, similar to that of water absorption, allows associating the electrical resistance measurement for the amount of the absorbed water by the use of a sensitivity factor
Matter-antimatter asymmetry induced by Barbero-Immirzi parameter
No full textWe review the baryon asymmetry generated in the early Universe in the framework of the metric-spinor gravity with the Holst term, which accounts for the Barbero-Immirzi parameter. For the generation of the matter-antimatter asymmetry, we have considered the model in which the time derivative of the Ricci scalar couples with matter currents (this model is known in the literature as gravitational baryogenesis). By using the current bounds on the parameter of the asymmetry, the ratio of baryon number to the entropy density, we infer a bound on the parameters characterizing the model under consideration (that is, the cosmological model in the presence of the torsion and Barbero-Immirzi parameter).(c) 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons .org /licenses /by /4 .0/). Funded by SCOAP3
NEW CONTRIBUTIONS ON THE DOME OF THE PANTHEON IN ROME: COMPARISON BETWEEN THE IDEAL MODEL AND THE SURVEY MODEL
No full textThis work proposes an integrated survey and a study of the intrados of the dome of the Pantheon in Rome. An actualized architectural survey of the interior of the dome can generate useful material for future studies.
The survey has been realized by using in a first stage the digital photogrammetry and in a second stage the three-dimensional laser scan technology. The compared analysis between different methods applied in the same object is useful towards a closer approximation to real dimension.
Among several aspects that arise in dealing with the Pantheon this work focuses mainly on the study of the geometry of the inner surface of the dome. The specific goal of the research is to verify the spherical form of the surface and the coffers' distribution. In this sense it takes an important place the extracting data system. In order to realize the analysis it was applied a critical treatment of selected information contained in the point cloud. The use of plan and section drawings connects to the study of three dimensional models.
The research is based on the construction of an ideal geometrical model that derives from the theoretical model described in the historical documents. The survey points model, which keeps the irregularities of the actual form, determines the creation of an average sphere, that is a regular model defined by clarifying geometrical laws.
The direct comparison between the survey model and the ideal model contributes to the building understanding. It detects irregularities or deformities where they exist, and provides objective and quantifiable data
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