83 research outputs found

    Determinazione di tossine algali (microcistine e nodularina) nelle acque superficiali

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    Viene proposto un metodo analitico per la determinazione dei principali congeneri delle microcistine (MCs) e della nodularina (NOD) presenti in campioni di acqua sia in fase disciolta (extracellulare) che all’interno delle cellule algali (endocellulare). Le due frazioni, extra ed endocellulare, vengono separate mediante filtrazione del campione acquoso. Le microcistine citoplasmatiche vengono estratte, previa procedura di congelamento-scongelamento della componente cellulare, con solvente organico in bagno ad ultrasuoni. Le tossine algali presenti nel campione in forma disciolta vengono invece concentrate mediante SPE (Solid-Phase Extraction) su fase C18. Entrambi gli estratti possono essere analizzati in HPLC-DAD, LC-MS o con il saggio ELISA

    An integrated hbim-gis digital environment for heritage preservation and enhancement in the inner italian territory

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    Depopulation in Italy is causing the marginalization of several inner territories and municipalities, with consequences for the preservation of different levels of heritage. The Italian National Strategy for Inner Areas (SNAI) aims to address these issues, but in some cases, the policies undertaken are not effective enough to improve development. In this context, the integration of Historic Building Information Modeling (HBIM) and Geographic Information System (GIS), as a potential solution in the enhancement of knowledge, information, and project management, could be an important resource to lean on. To investigate this aspect, the municipality of Dosso del Liro in the Northern part of Lake Como (Lombardy) has been chosen as a case study, based on its marginality and its territorial variety. The research methodology involves a combination of field data collection, bibliographical and archival investigations, database research, and digital recording of heritage, with the purpose of modelling and analyzing the territorial context on different aspects and at different scales. Precisely, multi-disciplinarity and multi-scalarity (but also multitemporality) are the key points for the HBIM-GIS modelling. Thus, trying to integrate and interpret in this innovative way the information acquired, the research aims to investigate the possibility of improvement for the creation of effective strategies and projects in the Inner Areas. The idea, in fact, is that with an increased knowledge and awareness of the heritage, the requirements for the design phase will be better in sight, and the quality of the intervention will be increased

    Static assessment of flawed notched components manufactured by L-PBF in AlSi10Mg: Experiments, computational approaches, a simplified method

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    The assessment of parts produced by Additive Manufacturing against static loading requires to account for several factors, such as process-induced defects and heterogeneous microstructure, which cause dependence of the material properties on the building position. In this work, a comprehensive approach to the static assessment of AlSi10Mg notched test articles manufactured by Laser Powder Bed Fusion (L-PBF) is presented. A test campaign on thin notched AlSi10Mg parts manufactured by L-PBF confirms that, despite the quasi-brittle tensile behaviour, an assessment based on elastic-plastic fracture mechanics parameters is needed to correctly predict the experimental failures. Predictions based on Failure Assessment Diagram and Theory of Critical Distances are then compared with experimental results. A simplified Imaginary Crack Model method, based on the concepts of Fictitious Crack Length, resulted to be quite precise and simple to apply

    Puerperio: conoscenze da parte delle ostetriche e informazione alle donne sul self-care

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    Il puerperio è il periodo di tempo che inizia subito dopo l'espulsione o estrazione della placenta e termina con la ripresa dell'attività ciclica ovarica. Convenzionalmente si assegna al puerperio una durata di 6-8 settimane, poiché in tale intervallo nonnalmente si completa la regressione della maggior parte delle modificazioni gravidiche a carico dei vari organi e apparati. Questo lavoro si prefigge l'obbiettivo di verificare le conoscenze che le ostetriche e le donne del puerperio hanno riguardo al self-care e di constatare la comunicazione di tali informazioni. È molto importante che la donna riceva dei consigli che la rendano autonoma rispetto a tutte le tematiche che riguardano il self-care in puerperio, quali: igiene, lochi, rapporti sessuali, contraccezione, allattamento, abitudini e allattamento, attivita' fisica, ginnastica perineale e psicologia. L'analisi conoscitiva è stata effettuata tramite somministrazione di questionari in forma anonima a 12 ostetriche e 76 puerpere dei due puerperi (fisiologico e a solvenza) della clinica Mangiagalli di Milano. I questionari erano costituiti da domande a risposta multipla in cui bisognava indicare le frasi corrette per gli argomenti sopra citati. La conoscenza delle ostetriche è risultata buona rispetto alla maggior parte degli argomenti presi in analisi e non sono state evidenziate particolari differenze tra ostetriche del puerperio fisiologico e ostetriche del puerperio a solvenza. Per quanto riguarda le puerpere, queste hanno delle conoscenze che possono essere definite insufficienti ad eccezione di due argomenti: allattamento e igiene personale. Quasi tutte le ostetriche affennano di educare la donna sulla maggior parte degli argomenti considerati, mentre le donne affermano che l'ostetrica non è un'importante fonte di informazione. La maggior parte di queste, infatti, afferma di non ricevere indicazioni durante la degenza in puerperio riguardo al self-care. L'unico argomento in cui le puerpere riconoscono un ruolo come educatrice all'ostetrica è l'igiene personale mentre l' allattamento viene trattato soprattutto dalla puericultrice

    Saturation temperature effect on heat transfer coefficient during convective boiling in microfin tubes

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    The growing attention on environmental aspects puts severe constraints on HVAC technology, mainly involving the working fluids and energy efficiency. Both are related to the main limiting factor of HVAC system: the heat transfer process, which, frequently, involves boiling and condensation. To provide suitable tools for the HVAC system design, it is necessary to gather information on the heat transfer characteristics of the new refrigerants. Particular interest is focused on R1234ze(e), because it is one of the viable options to face the R134a phase out. Something similar can be repeated for the low temperature ORC systems using a refrigerant as working fluid. Using a specifically designed test rig, heat transfer coefficient and pressure drop measures were performed during flow boiling of R1234ze(e). The operating conditions were defined by four parameters: the evaporation temperature (5 °C, 35 °C and 45 °C), the mass flux (two values were considered: 160 kg/m2s and 220 kg/m2s), the average thermodynamic quality (which varies between 0.25 and 0.75) and the quality change (which was fixed to 0.2). The uncertainty affecting the pressure drop and the heat transfer coefficient resulted lower than 1% and 5% respectively. The results highlighted that the saturation temperature strongly affects the heat transfer coefficient and the pressure drop: as a consequence of the saturation temperature increase from 5 °C to 45 °C, it was observed up to 40% heat transfer coefficient increase and 90% pressure drop reduction

    Radionuclide assessment of left ventricular function in patients with myocardial infarction and diabetes mellitus

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    The aim of this study was to compare left ventricular function, assessed by radionuclide angiocardiography, in 54 diabetics and 194 non-diabetics with acute myocardial infarction (AMI). The most meaningful results concern the inferior AMI group, whose left ventricular ejection fraction (LVEF) and regional wall motion were significantly lower in diabetics than in non-diabetics (LVEF was 44.2 +/- 11 vs. 51.6 +/- 9%, P less than 0.005; the regional wall motion score was 0.46 +/- 1 vs. 1.56 +/- 1, P less than 0.01, respectively), while no significant difference was observed in the anterior AMI group. However, in the group as a whole, the LVEF was 41 +/- 13% in diabetics and 47 +/- 13% in non-diabetics (P less than 0.01), the number of abnormally contracting segments was 2.0 +/- 0.9 and 1.5 +/- 1, respectively, and the wall motion score was 0.2 +/- 1.1 and 1.0 +/- 1.4, respectively (P less than 0.01). These data could be explained by an underlying cardiac dysfunction in diabetes, in addition to AMI. The more marked difference between diabetics and non-diabetics in inferior AMI might be related to the smaller infarct size in this group

    Variability of microcystin cell quota in metapopulations of Planktothrix rubescens: causes and implications for water management

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    In this study, we investigated the relationships between microcystin (MCs) concentrations and the biovolumes of Planktothrix rubescens (BPr) in 2 natural lakes (Pusiano and Garda) and 2 artificially dammed reservoirs (Occhito and Ledro) in Italy. In all the considered water bodies, P. rubescens was the dominant cyanobacterium. All the lakes were characterized by significant relationships between MCs and BPr, with limited variability in the MC quota (the content of MCs per unit of biovolume) within each water body compared with the variability between sites. The results were consistent with the development of specific MC-genotypes, with moderate seasonal and spatial changes in the proportion between toxic and non-toxic strains. The MC cell quota obtained in our work (ECQ, Environmental Cell Quota) were in the same range of values computed on the basis of analyses made on environmental samples dominated by P. rubescens or P. agardhii, and on isolates of the same two species (< 1 to over 10 μg mm-3). Besides the usual ordinary least square regressions, models have been evaluated by using quantile regression, a method that allows estimating the conditional median or other quantiles of the response variable. We showed that the use of quantile regressions has different advantages, which included the computation of MC quota based on the whole range of available data, the robustness against outliers, and the ability to estimate models also in cases where there is no or only weak relationships. The highest ECQ values estimated from 95% quantile regressions in specific water bodies might be used to estimate the worst-case MC concentrations from algal abundances. Nevertheless, it was stressed that a realistic assessment of toxicity and potential adverse health effects necessarily should take into account the toxicity potential of the more abundant MC-congeners produced by specific cyanobacteria population

    A 10 Gb/s CMU in SiGe BiCMOS commercial technology with multistandard capability

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    A 10 Gb/s CMU has been fabricated in a commercial SiGe BiCMOS technology featuring multistandard compliance with SDH/SONET and 10 GbE specifications,dual reference clock frequency and output jitter below 80 mUIpp.The phase tracking loop uses a charge pump with low common mode current to minimize frequency ripple.Power supply is 2.5 and 3.3 V and the total power consumption is below 480 mW
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