1,354,123 research outputs found
EXTRA HIGH ACCURACY FITTING OF THE PES FOR SUB-PERCENT CALCULATION OF INTENSITIES
No full textCalculation of rotation-vibration line intensities with sub-percent
accuracy has recently become a standard requirement for the
applications in retrieval and monitoring of gases in the Earth's
atmosphere and potentially in the atmospheres of exoplanets. A major
factor in the accurate calculation of intensities is the requirement
for a high accuracy \textit{ab initio} Dipole moment surface (DMS)
(e.g. references \footnote{L.Lodi, J. Tennyson and O.L. Polyansky, \textit{Journal of Chemical Physics}, \textbf{135}, 034113, (2011) } and \footnote{ O.L. Polyansky, K. Bielska, M. Ghysels, L. Lodi, N.F.Zobov, J.T.Hodges, J. Tennyson \textit{ Physical Review Letters}, \textbf{114}, 243001, (2015) }).
We demonstrate here that the change from
the ”good” potential energy surface (PES) to ”excellent” PES, used for the
intensity calculations is also important. By ”good” we mean here,
for example, the PES a standard deviation of 0.025 \wn and by
”excellent” - the PES with the standard deviation 0.011 \wn. Details of
studies on \chem{H_2O}\footnote{I.I Mizus, A.A. Kyuberis, N.F. Zobov, V.Y. Makhnev, O.L. Polyansky and J. Tennyson \textit{Phil. Trans. R. Soc. A}, \textbf{376}, 20170149, (2018)}, \chem{O_3} \footnote{O.L.Polyansky, N.F. Zobov, I.I Mizus, A.A. Kyuberis. L. Lodi and J. Tennyson \textit{JQSRT},\textbf{ 210}, 127-135 (2018)},
\chem{HCN} and \chem{CO_2} molecules will be presented in the talk
The Thursday Murder Club: Launching a megabrand author - a publishing case study
Full text linkIn 2020, the Christmas book charts in the UK made headlines: Barack Obama’s eagerly awaited autobiography, The Promised Land, was beaten to the top spot by The Thursday Murder Club by Richard Osman, a debut cosy crime novel set in a retirement village. Not only did Osman’s book beat the former US president’s expected bestseller, it also broke records, becoming the fastest-selling debut crime novel of all time. Although Osman has a certain level of fame in the UK from his TV appearances on shows such as Pointless, his celebrity status does not entirely explain the novel’s huge sales. This article tracks the acquisition, publication, and promotion journey of The Thursday Murder Club in order to understand the industry and cultural context of its success and to interrogate the role of celebrity in the creation of author brands. The findings suggest that the unexpected scale of the success of the book owed to a number of factors, including in-depth editing by the novel’s agent, editor, and author to tighten up the plot, an extensive and strategic promotional campaign, the pandemic (which drove interest in the book’s genre and themes), and the quality of the writing. We find that the book’s success was accentuated by Osman’s celebrity status rather than being entirely reliant on it. This research adds to the growing scholarship on celebrity authorship by means of an in-depth case study and provides insight into the processes behind publishing a ‘celebrity’ book and launching a megabrand author
Detection of weak stochastic forces in a parametrically stabilized micro-optomechanical system
Full text linkMeasuring a weak force is an important task for micromechanical systems, both when using devices as sensitive detectors and, particularly, in experiments of quantum mechanics. The optimal strategy for resolving a weak stochastic signal force on a huge background (typically given by thermal noise) is a crucial and debated topic, and the stability of the mechanical resonance is a further, related critical issue. We introduce and analyze the parametric control of the optical spring, which allows us to stabilize the resonance and provides a phase reference for the oscillator motion, yet conserving a free evolution in one quadrature of the phase space. We also study quantitatively the characteristics of our micro-optomechanical system as detector of stochastic force for short measurement times (for quick, high-resolution monitoring) as well as for the longer-term observations that optimize the sensitivity. We compare a simple strategy based on the evaluation of the variance of the displacement which is a widely used technique) with an optimal Wiener-Kolmogorov data analysis. We show that, due to the parametric stabilization of the effective susceptibility, we can more efficiently implement Wiener filtering, and we investigate how this strategy improves the performance of our system. We finally demonstrate the possibility to resolve stochastic force variations well below 1% of the thermal noise.MicroelectronicsElectrical Engineering, Mathematics and Computer Scienc
A principal in transition: an autoethnography
Full text linkThis research represents a highly personalized account of the complexities,
interpretations, and reflections of a principal in transition from one elementary school to
another elementary school in the same district. Using myself as the subject and the
researcher in the social context of an elementary school provided the impetus for this
self-study. Through an insider's vantage point, I have chronicled and traced the
experiences of my own administrative transition using the qualitative methodology of
autoethnography. This genre of qualitative research brings the reader closer to the
subculture studied through the experiences of the author. While every campus and
district has its own unique culture and environment, the introspection and evaluation
provided by the methodology of autoethnography greatly facilitates an understanding of
the processes of transition. The experiences I have encountered, the problems I face, and
the interpretations derived from them will strengthen my own practice as a public school
administrator and provide insight into the ever-changing administrative position called
the principalship. Data gathering consisted of a reflexive journal, my personal calendar, faculty
agendas, staff memos, and reflective analysis. At the completion of the school year
common strands, key attributes, and coding of the data served to provide retrospective
insights. These research tools were used to capture the experiences of my administrative
transition.
The results of this study were expressed in a personal narrative that comprises
Chapters IV through VI. Chapters I through III present a traditional dissertation model
that includes the introduction, review of literature, and research methodology. Chapter
VII offers recommendations, a discussion of the findings and concluding remarks
"Y'all come and have fun": discovering a New Jersey country and western music scene in a box of postcards
No full textSeveral years ago, Rutgers University's Special Collections and University Archives was given a checkbox containing fifty-six postcards advertising country and western music shows at venues around New Jersey. The postcards, primarily from the 1960s, promoted shows featuring Grand Ole Opry stars like Wanda Jackson, Hank Thompson, and Elton Britt. Preliminary research revealed that the postcards touted performances by regional and local musicians, as well. A closer look at the cards began to expose how a small, hyper-local ephemeral collection could bring to light and contribute to a larger history; in this case, a once thriving but little explored New Jersey country and western music scene. The research that forms this article focuses on one venue, the Copa Club in the city of Secaucus, and its owners, brothers and musicians Shorty and Smokey Warren, as a specific case study. This collection of postcards, like so much ephemeral material in archives, could have remained undervalued and under-researched. In this case, a close consideration set forth a journey that included research in local archives and interviews with scene participants. As a result, this article explores the past of an important musical genre that evolved along with social changes in the United States. This piece contributes to the scholarship around uses and value of ephemera, as well as scholarship that continues to challenge the southern origin story of country music and examine vital locales of country music outside the South.Peer reviewe
Author, publisher and bookseller : a tripartite synergy in Nigerian book industry
Full text linkThis work is about the roles of Author, Publisher and Bookseller in Book development in
Nigeria. The paper started by delving into the history of Book Publishing in Nigeria after
which it proceeded by defining who an author, a publisher, and a bookseller is and
expatiated on the indispensable roles of these key actors in Nigerian Book Industry and in
the emerging Information Society. Furthermore, the various constraints to book
development were identified while the paper advised on how the Book Industry can be
further promoted in Nigeria. However, the paper concluded and made recommendations
on how the Book sector can help in enhancing scholarship in the country
\u27Letters Full of Love\u27: Wayne Booth\u27s Theories of the Implied Author and Reader in Brad Marsh\u27s WWII Correspondence
No full textThis project consists of a qualitative study of the WWII correspondence of Captain Brad Marsh from the collection of letters donated by his daughter on April 26, 2013. I draw from the narrative theory and works of Wayne Booth to examine Marsh’s construction of self as an implied author by examining how he presents his experiences and portrays his emotions. I also examine how Marsh constructs his implied self by paying attention to details such as the information he shares with Lynn and how he presents it. I explore the nature of the implied author and reader in the correspondence and also how the relationship between the implied writer and reader influences the understanding of an unintended audience
Mood disorders in familial epilepsy: A test of shared etiology
No full textObjective: Mood disorders are the most common comorbid conditions in epilepsy but the cause remains unclear. One possible explanation is a shared genetic susceptibility to epilepsy and mood disorders. We tested this hypothesis by evaluating lifetime prevalence of mood disorders in relatives with and without epilepsy in families containing multiple individuals with epilepsy, and comparing the findings with rates from a general population sample.
Methods: The Composite International Diagnostic Interview was administered to 192 individuals from 60 families, including 110 participants with epilepsy of unknown cause (50 focal epilepsy [FE], 42 generalized epilepsy [GE], 6 FE and GE, 12 unclassifiable) and 82 relatives without epilepsy (RWOE). Odds ratios (ORs) for lifetime prevalence of mood disorders in participants with versus without epilepsy were computed through logistic regression, using generalized estimation equations to account for familial clustering. Standardized prevalence ratios (SPRs) were used to compare prevalence in family members with general population rates.
Results: Compared with RWOE, ORs for mood disorders were significantly increased in participants with FE (OR = 2.4, 95% confidence interval [CI] = 1.1 - 5.2) but not in those with GE (OR = 1.0, 95% CI = 0.4 - 2.2). In addition, prevalence of mood disorders was increased in individuals with epilepsy who had ≥1 relative with FE. Compared with general population rates, mood disorders were significantly increased in individuals with FE but not in those with GE. Rates were also increased in RWOE, but not significantly so (SPR = 1.4, P = 0.14).
Significance: These findings are consistent with the hypothesis of shared genetic susceptibility to epilepsy and mood disorders, but suggest (1) the effect may be restricted to FE, and (2) the shared genetic effect on risk of mood disorders and epilepsy may be restricted to individuals with epilepsy, that is, to those in whom the genetic risk for epilepsy is “penetrant.”Peer reviewedThis is the accepted version of the following article: Insel BJ, Ottman R, Heiman GA. Mood disorders in familial epilepsy: A test of shared etiology. Epilepsia. 2018;00:1–9. https://doi.org/10.1111/epi.13985, which has been published in the Early View form at http://onlinelibrary.wiley.com/doi/10.1111/epi.13985/full. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [https://authorservices.wiley.com/author-resources/Journal-Authors/licensing-open-access/open-access/self-archiving.html]
Product Hopping: A New Framework
No full textOne of the most misunderstood and anticompetitive business behaviors in today’s economy is “product hopping,” which occurs when a brand-name pharmaceutical company switches from one version of a drug to another. These switches, benign in appearance but not necessarily in effect, can significantly decrease consumer welfare, impairing competition from generic drugs to an extent that greatly exceeds any gains from the “improved” branded product. The antitrust analysis of product hopping is nuanced. It implicates the intersection of antitrust law, patent law, the Hatch-Waxman Act, and state drug product selection laws. In fact, the behavior is even more complex because it occurs in uniquely complicated markets characterized by doctors who choose the product but don’t pay for it, and consumers who buy the product but don’t choose it. It is thus unsurprising that courts have offered inconsistent approaches to product hopping. They have paid varying levels of attention to the regulatory structure, offered a simplistic analysis of consumer choice, adopted an underinclusive antitrust standard based on coercion, and focused on whether the brand firm removed the original drug from the market. Entering this morass, we offer a new framework that courts, government enforcers, plaintiffs, and manufacturers can employ to analyze product hopping. This rigorous and balanced framework is the first to incorporate the economic characteristics of the pharmaceutical industry. For starters, it defines a “product hop” to include only those instances in which the brand manufacturer (1) reformulates the product in a way that makes the generic non-substitutable and (2) encourages doctors to write prescriptions for the reformulated product rather than the original. The test also offers two safe harbors, which are more deferential than current caselaw, to ensure that the vast majority of reformulations will not be subject to antitrust scrutiny. The analysis then examines whether a brand’s product hop passes the “no-economic-sense” test. In other words, would the reformulation make economic sense for the brand if it did not have the effect of impairing generic competition? Merely introducing new products would pass the test. Encouraging doctors to write prescriptions for the reformulated rather than the original product—“cannibalizing” the brand’s own sales—might not. Imposing antitrust liability on behavior that does not make business sense other than through its impairment of generic competition offers a conservative approach and minimizes “false positives” in which courts erroneously find liability. Showing just how far the courts have veered from justified economic analysis, the test would recommend a different analysis than that used in each of the five product-hopping cases that have been litigated to date, and a different outcome in two of them. By carefully considering the regulatory environment, practicalities of prescription drug markets, manufacturers’ desire for clear-cut rules, and consumers’ needs for a rule that promotes price competition without deterring valued innovations, the framework promises to improve and standardize the antitrust analysis of product hopping
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