28 research outputs found
Latency Analysis and Reduction in a 4G Network
No full text5G, the next generation of mobile network, is expected to be launched commercially around 2020. Compared to the present generation – 4G mobile network, a significant improvement in terms of performance and reliability is considered for 5G. One of the important factor in the design of 5G is – about 10 times lower packet latency than 4G. Some of the use cases identified for 5G require packet latency as low as 1 ms. Such stringent latency targets are essential to enable new services like virtual reality streaming of live content over mobile network, automated vehicle platooning over mobile network and tactile internet where machines and tools can be controlled remotely with extreme responsiveness over the mobile network.The main goal of this thesis is to understand how packet latency is affected by the various factors observed in a realistic environment. In contrast to lab environments, where the packet latency reported would be very low, a consolidated study on the various factors affecting packet latency in a 4G (LTE) network in a realistic environment is missing. To this extent, the results of this work have enabled to identify the various factors affecting packet latency in a realistic 4G network. This further led to identifying the latency contribution of the various components to the overall packet latency. Later on, two different latency reduction techniques were evaluated to verify the possible latency reduction achievable on a 4G network, using those two techniques.To reduce packet latency to achieve the latency targets for 5G, first it was necessary to identify how packet latency is caused and affected in a 4G network. This work was aimed at achieving this goal. As the latency reduction techniques were evaluated at their best configuration in terms of latency, results from the latency reduction techniques also identifies the lower limit of latency improvement achievable in a 4G network. The inference from the results suggests that in order to achieve the latency targets specified for 5G networks, a redesigned radio access technology of 4G is essential.Electrical Engineering | Telecommunications and Sensing System
Author Correction: ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression
No full textCorrection to: Nature Communications, published online 17 August 2023 The original version of this Article contained an error in Fig. 2g, in which image for 5dpi Ctrl condition was inadvertently duplicated and the correct image for 5dpi iKO condition was originally omitted. This error has been corrected in both the PDF and HTML versions of the Article.</p
Indonesian kalkulator of oocytes (IKO): A smart application to determine our biological age
No full textThe Viewpoint on Japan by a Certain Chinese Author in Southeast Asia
No full textAt present much of news media are classifying China, Korea and North Korea as "Anti-Japan" countries, while the rest of Asian countries as "Pro-Japan" countries. However, even the countries classified as "Pro-Japan", in fact, consist of various races. Therefore the understanding of the past war can differ depending on the race and sometimes even on the respective individuals. In short, the recent "Friend or Enemy" type classification by media seems to be too simplifying the situatio
On “A class Teacher” by Liu Xinwu
No full textLiu Xinwu is the author I studied in my master's thesis and still arouses my deep contemplation.A class Teacher",which brought him into prominence, was widely referred to, because of its positive negation of the obscurantist policy in those days when the Great proletarian cultural Revolution was not objectively appraised yet. However, even at present, 30years since then, still Chinese overnment controls the information, making only the pro-government information be available to the public
The role of intestinal stearoyl-CoA desaturase 1 in intestinal and systemic lipid and energy metabolism
No full textStearoyl-CoA desaturase 1 (SCD) is an endoplasmic reticulum-residing enzyme that converts saturated fatty acids into monounsaturated fatty acids through the insertion of a double bond at the 9 position. This conversion of saturated fatty acids (SFA) to monounsaturated fatty acids (MUFA) is a key and highly regulated step in lipid metabolism because the MUFA products of SCD1 are the preferred substrates for the synthesis of other lipid species, including triacylglycerols (TAG), cholesterol esters (CE), phospholipids (PL), and diacylglycerols (DAG). Prior studies have shown that disruptions to SCD1 lead to alterations in esterified lipids, protection from diet-induced obesity, increased energy expenditure and improved glucose tolerance. Given the important roles the intestine plays in the digestion, absorption, and secretion of nutrients into the body, and as a regulatory and signaling organ, the specific contributions of intestinal SCD1 to systemic lipid metabolism and energy balance were investigated. SCD1 gene and protein expression was found to be expressed along the length of the intestine, with the greatest expression in the distal small intestine and colon. Intestinal SCD1 is also regulated in a nutritional manner, as seen in mice fasted then refed a high-sucrose diet which upregulates SCD1 in each segment of the intestine, particularly in the distal intestine. Given the spatial and nutritional regulation of intestinal SCD1, we generated intestine-specific knockout (iKO) mice to assess the specific contribution of intestinal SCD1 to whole-body lipid and energy metabolism. This deletion did not have significant impacts on body weights, body composition, intestinal fat absorption or motility. Lipidomic analyses of the intestine revealed that intestinal SCD1 modulates intestinal lipid content particularly TAGs and CEs in the proximal and distal small intestine. Intestinal SCD1 also regulates plasma lipid content and hepatic lipid composition, with notable reductions in the 14:1/14:0 desaturation ratio. This reduction in myristoleate may mediate reductions in hepatic expression of the Pgc1a-Sirt1 axis and fatty acid oxidation. Given prior reports of Scd1 deficient animals being protected from diet-induced obesity due to increased energy expenditure, and our findings that intestinal SCD1 regulates intestinal and systemic lipid metabolism, the role of intestinal SCD1 in systemic energy balance was investigated. iKO mice were maintained on a chow diet or fed a 45% high-fat diet (HFD) for metabolic profiling. Chow fed iKO mice had increased plasma and hepatic bile acid content and decreased fecal bile acid excretion. Notably, expression of apical sodium dependent bile acid transporter (Asbt) was increased in iKO mice, potentially mediating increased ileal uptake of bile acids. This altered bile acid profile was associated with increased expression of Takeda G protein-coupled receptor 5 (TGR5) signaling targets, including Dio2 in brown adipose tissue and plasma glucagon-like peptide 1 (GLP-1). iKO mice on a HFD had reduced metabolic efficiency due to decreased weight gain despite increased food consumption. HFD-fed iKO mice had increased energy expenditure and improved glucose tolerance. Altogether, these studies indicate an important role of intestinal SCD1 on modulating intestinal and whole-body lipid content and composition and suggest a role for intestinal SCD1 in the regulation of bile acid and energy homeostasis.Ph.D.Includes bibliographical reference
The Viewpoint on Japan by a Certain Chinese Author in Southeast Asia
Get PDFAt present much of news media are classifying China, Korea and North Korea as "Anti-Japan" countries, while the rest of Asian countries as "Pro-Japan" countries. However, even the countries classified as "Pro-Japan", in fact, consist of various races. Therefore the understanding of the past war can differ depending on the race and sometimes even on the respective individuals. In short, the recent "Friend or Enemy" type classification by media seems to be too simplifying the situationdepartmental bulletin pape
About the Southeast Asia Chinese Literature and "Anti-fascism"
No full textLast year in China, there were a lot of commemorative activities to celebrate the “70th anniversary of the victory of the anti-fascism”. Chinese Chairman Xi Jinping participated in the military parade which was held to celebrate the “70th anniversary of the victory of the anti-fascism”. Even for Japanese, it is still a fresh memory. This is also reflected on various ceremonies in China. The author of this article is a member of the Southeast Asia Chinese Literature Research Society. The seminars of the research were held last year as “the Forum of Southeast Asia Anti-fascist Literature in Chinese, and for the 11th Southeast Asia Chinese Literature Symposium. The seminar started with the comment “China and the Southeast Asia shared the sufferings of the anti-Japanese”.For most of the Japanese, it is necessary to realize that China has been trying hard to share the “historical consciousness” with the surrounding countries obviously in recent years
On “A class Teacher" by Liu Xinwu
Get PDFLiu Xinwu is the author I studied in my master's thesis and still arouses my deep contemplation.A class Teacher",which brought him into prominence, was widely referred to, because of its positive negation of the obscurantist policy in those days when the Great proletarian cultural Revolution was not objectively appraised yet. However, even at present, 30years since then, still Chinese overnment controls the information, making only the pro-government information be available to the public.departmental bulletin pape
About the Southeast Asia Chinese Literature and "Anti-fascism"
Get PDFLast year in China, there were a lot of commemorative activities to celebrate the “70th anniversary of the victory of the anti-fascism". Chinese Chairman Xi Jinping participated in the military parade which was held to celebrate the “70th anniversary of the victory of the anti-fascism". Even for Japanese, it is still a fresh memory. This is also reflected on various ceremonies in China. The author of this article is a member of the Southeast Asia Chinese Literature Research Society. The seminars of the research were held last year as “the Forum of Southeast Asia Anti-fascist Literature in Chinese, and for the 11th Southeast Asia Chinese Literature Symposium. The seminar started with the comment “China and the Southeast Asia shared the sufferings of the anti-Japanese".For most of the Japanese, it is necessary to realize that China has been trying hard to share the “historical consciousness" with the surrounding countries obviously in recent years.departmental bulletin pape
