162,394 research outputs found

    Synovial tissue macrophages: friend or foe?

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    Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce pathogenic tumour necrosis factor. During sustained remission, the synovial tissue macrophage numbers recede to normal. The constitutive presence of tissue macrophages in the lining layer of the synovial membrane in healthy donors and in patients with RA during remission suggests that this macrophage population may have a role in maintaining and reinstating synovial tissue homeostasis respectively. Recent appreciation of the different origins and functions of tissue-resident compared with monocyte-derived macrophages has improved the understanding of their relative involvement in organ homeostasis in mouse models of disease. In this review, informed by mouse models and human data, we describe the presence of different functional subpopulations of human synovial tissue macrophages and discuss their distinct contribution to joint homeostasis and chronic inflammation in RA

    Wpływ galaktooligosacharydów na behawior i wybrane parametry układu białokrwinkowego u szczurów w warunkach elektrycznej stymulacji jądra środkowego ciała migdałowatego

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    Ruciński J., Kurowska E., Podlacha M., Stankiewicz A., Myślińska D., Jaskulski M., Jurkowlaniec E. Wpływ galaktooligosacharydów na behawior i wybrane parametry układu białokrwinkowego u szczurów w warunkach elektrycznej stymulacji jądra środkowego ciała migdałowatego, w: Nauki przyrodnicze, cz. 11 / Nyćkowiak Jędrzej , Leśny Jacek (red.), Badania i Rozwój Młodych Naukowców w Polsce , 2018, Młodzi Naukowcy, ISBN 978-83-66139-42-8, ss. 92-98

    [Report to Chief J. E. Curry, by an unknown author #1]

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    Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney

    [Report to Chief J. E. Curry, by an unknown author #2]

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    Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney

    Murder on the mountain: author talk with Peter J. Wosh

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    Author talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.

    Mr. Melvin J. Collier, RWWL AUC, June 2011

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    This video is a conversation with Mr. Melvin J. Collier. Mr. Collier talks about his book, "From Mississippi to Africa: A Journey of Discovery". Daniel Le, AUC Woodruff Library, is the interviewer

    A Tripartite Post-Recession Rebalancing

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    In this latest Advance & Rutgers Report, entitled “A Tripartite Post-Recession Rebalancing,” Dean James W. Hughes and Professor Joseph J. Seneca deliver an incisive assessment of the current market conditions and obstacles in the path of our economic recovery. They offer a statistical cautionary tale that the private and public sector need to hear and acknowledge in order for the economy to make continued progress.This report was published as Issue Paper Number 7, November 2011, in Advance & Rutgers Report
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