109 research outputs found
DISTRIBUTION NETWORK RECONFIGURATION AND RECONSTRUCTION FOR POWER LOSS MINIMIZATION USING GENEROUS TRANSFORMATIVE OPTIMIZATION STRATEGY
No full textSwetha G1, Dr. R Prakash2, Sunil Kumar AV
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
No full textThis dataset contains Key analysis and plotting scripts, data, and sample images. 3-D T1 relaxation time measurements in equine model of post-traumatic osteoarthritis using MB-SWIFT Journal of Orthopaedic Research | DOI: 10.1002/jor.25629 Swetha Pala (1), Nina Hänninen (1,2), Ali Mohammadi(1), Mohammadhossein Ebrahimi (1,2), Nikae C.R. te Moller(3), Harold Brommer(3), P. René van Weeren (3), Janne T.A. Mäkelä (1), Rami K. Korhonen (1), Isaac O. Afara(1), Juha Töyräs (1,4,5), Santtu Mikkonen (1), Mikko J. Nissi (1*), Olli Nykänen (1,2) 1Department of Applied Physics, University of Eastern Finland 2Research Unit of Medical Imaging, Physics and Technology, University of Oulu 3Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University 4Science Service Center, Kuopio University Hospital, Kuopio, Finland 5School of Information Technology and Electrical Engineering, The University of Queensland *Corresponding author Mikko J. Nissi Department of Technical Physics University of Eastern Finland, Kuopio Finland POB 1627 70211 Kuopio [email protected] +358-50-5955517 Running title: ‘3D T1 of mild PTOA using MB-SWIFT’ Keywords: Quantitative MRI, T1 relaxation, equine model,post-traumatic osteoarthritis, proteoglycan content. Included folders and files are: - Article_figures: all figures published in the manuscript (.svg format) - Data: Raw MRI data files per flip angle (phase & magnitude images) from 28 samples and corresponding fitted T1 maps within respective folders. SPSS structured data files used for statistical analysis. - Matlab scripts: Matlab functions used for data processing and T1 computation, aedes plugins, and data analysis with subfolders and files: - aedes_plugins: plugins for aedes (http://aedes.uef.fi) and scripts for calculation of surface visualisations from relaxation time maps and auto-segmented mesh. - Data processing and T1 computation: Scripts for non-linear 3D T1 fitting. - Analysis: Key scripts used for analysis and plotting. - README.txt: this file describing the contents of the dataset. See more info in separate readme files included in sub-folders. (Swetha Pala, 31May 2023
A joint clipping and logarithmic based companding for the reduction of peak-to-average power ratio in OFDM system
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Fabrication, structure and optical characterization of Ce filled CoSb3 nanostructure by solvothermal method
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Correlation between retinal sensitivity and cystoid space characteristics in diabetic macular edema
No full textPurpose: To evaluate the correlation between retinal sensitivity and cystoid space characteristics in eyes with diabetic macular edema (DME). Materials and Methods: Prospective cross-sectional study of 22 subjects with DME (32 treatment-naïve eyes). All study subjects underwent complete ophthalmic examination, including slit-lamp biomicroscopy and dilated fundus examination. All subjects underwent spectral domain optical coherence tomography (SD-OCT) and microperimetry (MP). Intraretinal cystoid space (ICS) volume was generated after manual delineation of cystoid space boundaries using the three-dimensional-OCT software. Various SD-OCT parameters, including retinal thickness, retinal volume, cystoid space volume, cystoid space intensity, and outer retinal structure integrity, were correlated with MP parameters and best-corrected visual acuity (BCVA). Results: Subject′s mean age was 57 ± 9 years. The mean logarithm of minimum angle of resolution BCVA was 0.4 ± 0.2. The intraclass correlation coefficient for inter- and intra-grader assessment of cystoid space volume by manual delineation was 0.99 and 0.99, respectively. Mean total ICS volume was 0.4 ± 0.4 mm 3 and for the foveal center, subfield was 0.1 ± 0.1 mm 3 . Mean retinal sensitivity was 12.89 ± 10 dB; however, foveal retinal sensitivity was 12.3 ± 11.1 dB. We found no significant correlation between BCVA and total cystoid space volume (r = 0.33, P = 0.06). Correlation between total retinal sensitivity and total ICS was negative and nonsignificant (r = −0.17, P = 0.36). Correlation between foveal retinal sensitivity and foveal cystoid space intensity was moderate and marginally significant (r = −0.43, P = 0.05). Conclusion: Total cystoid space volume was not significantly correlated with BCVA or total retinal sensitivity in subjects with DME. Foveal cystoid space optical intensity was negatively correlated with foveal retinal sensitivity. These findings suggest further investigation of cystoid space characteristics in the setting of DME may be of value
Power Control in Ad Hoc Wireless Networks: An Architectural Solution for a Melee of Multiple Agents, Cost Criteria, and Information Patterns
No full textCommunal diversity of Endophytic fungi among various Medicinal Plants
No full text<p><strong>Abstract:</strong> Medicinal plants have been traditionally utilized by marginalized communities for curing a broad range of health conditions. In traditional medicine, a range of well-being issues are addressed by utilizing different tissues from medicinal plants. . Each tissue of these medicinal plants produces variety of secondary metabolites with pharmacological effects. These tissues also harboures many endophytes that stimulates the growth and secondary metabolite production by the plants. The medicinal plants namely Andrographis paniculata, Abutilon indicum, Ipomea lacunose Aeglemarmelos,Ocimum,Withania sominifera ,Tinospora are some of the important medicinal plants with a variety of applications like anticancer properties, immunomodulatory effects, anti-hepatotoxic qualities, anti-atherosclerotic attributes, anti-hyperglycemic potential, and antioxidative activities, anti-hyperglycemic potential, anti-convulsant activity and larvicidal activities These medicinal plants have demonstrated the existence of promising endophytic strains with potential applications for enhancing crop growth and addressing oxidative stress. This study aims to uncover the diversity of endophytes residing within these medicinal plants</p><p><strong>Keywords:</strong> Endophytic fungi, Medicinal plants, bioactive compounds, Microbial diversity.</p><p><strong>Title:</strong> Communal diversity of Endophytic fungi among various Medicinal Plants</p><p><strong>Author:</strong> Swetha Vallabhaneni, Lakshmi Sharvani K.S, Guru Prasad C, Siva Prasad B.V, Durbaka V R Prasad, Vijaya Lakshmi D</p><p><strong>International Journal of Life Sciences Research</strong></p><p><strong>ISSN 2348-313X (Print), ISSN 2348-3148 (online)</strong></p><p><strong>Vol. 11, Issue 4, October 2023 - December 2023</strong></p><p><strong>Page No: 9-19</strong></p><p><strong>Research Publish Journals</strong></p><p><strong>Website: www.researchpublish.com</strong></p><p><strong>Published Date: 18-November-2023</strong></p><p><strong>DOI: </strong><a href="https://doi.org/10.5281/zenodo.10153311"><strong>https://doi.org/10.5281/zenodo.10153311</strong></a></p><p><strong>Paper Download Link (Source)</strong></p><p><a href="https://www.researchpublish.com/papers/communal-diversity-of-endophytic-fungi-among-various-medicinal-plants"><strong>https://www.researchpublish.com/papers/communal-diversity-of-endophytic-fungi-among-various-medicinal-plants</strong></a></p>
СУЧАСНИЙ СТАН СТВОРЕННЯ, ВИРОБНИЦТВА ТА ДОСЛІДЖЕННЯ ТАБЛЕТОВАНИХ ЛІКАРСЬКИХ ПРЕПАРАТІВ Повідомлення 20. Характеристика процесу створення та дослідження гастроретентивних систем доставки лікарських речовин.
No full textMODERN STATE OF CREATION, PRODUCTION AND RESEARCH OF DRUGSM.B. Demchuk, N.P. Darzuli, T.A. Hroshovyi, S.V. Demchuk1TernopilStateMedicalUniversityby I.Ya. Horbachevsky1JSC “Ternopharm”Notice 20. The characteristic of process of creating and research of gastroretentive drug delivery system.Summary: the literature on the benefits of the use and technological aspects of obtaining gastroretentive drug delivery system, such as floating, high density (sinking), mucoadhesive and magnetic systems, super porous hydrogel and matrix systems are summarized.Keywords: gastroretentive drug delivery system, gastrointestinal tract, intragastric floating systems.Introduction. Oral administration is the most convenient and preferred means of any drug delivery to the systematic circulation. Dosage forms with a prolonged gastric residence time, i.e. gastro retentive dosage forms (GRDFs), will provide us with new and important therapeutic options. GRDFs extend significantly the period of time over which the drug may be released. Thus, they not only prolong dosing intervals, but also increase patient compliance beyond the level of existing controlled release dosage forms. Gastroretentive drug delivery is an approach to prolong gastric residence time, thereby targeting site-specific drug release in the upper gastrointestinal tract for local or systemic effects. Prolonged gastric retention improves bioavailability, reduces drug waste, and improves solubility for drugs that are less soluble in a high pH environment. It has applications also for local drug delivery to the stomach and proximal small intestine. The most important parameters which has impact on the gastric retention time of oral dosage forms include: density, size and shape of the dosage form, food intake and its nature, caloric content and frequency of intake, posture, gender, age, sex, sleep, body mass index, physical activity and diseased states of the individual (e.g. chronic disease, diabetes etc.) and administration of drugs with impact on gastrointestinal transit time.Various attempts have been made to retain the dosage form in the stomach as a way of increasing the retention time. These attempts include introducing floating dosage forms (gas-generating systems and swelling or expanding systems), mucoadhesive systems, high-density systems, modified shape systems, gastric- emptying delaying devices and co administration of gastric emptying delaying drugs.Floating drug delivery systems have a bulk density less than gastric fluids and so remain buoyant in the stomach without affecting gastric emptying rate for a prolonged period of time. While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the system. Floating drug delivery systems can be divided into non effervescent and gasgenerating (effervescent) system.High density (sinking) or non- floating drug delivery systems have the density that must exceed density of normal stomach content (~ 1.004 gm/cm3). These formulations are prepared by coating drug on a heavy core or mixed with inert materials such as iron powder, barium sulphate, zinc oxide and titanium oxide etc.Bioadhesive drug delivery systems (BDDS) are used as a delivery device within the lumen to enhance drug absorption in a site specific manner. This approach involves the use of bioadhesive polymers, which can adhere to the epithelial surface in the stomach. Materials commonly used for bioadhesion are polyacrylic acid, chitosan, cholestyramine, sodium alginate, hydroxypropyl methylcellulose, sucralfate, tragacanth, dextrin, polyethylene glycol and polylactic acids etc.Super porous hydrogel systems. In this approach to improve gastric retention time super porous hydrogels of average pore size >100 micro miter, swell to equilibrium size within a minute due to rapid water uptake by capillary wetting through numerous interconnected open pores.Magnetic systems. This approach to enhance the gastric retention time is based on the simple principle that the dosage form contains a small internal magnet, and a magnet placed on the abdomen over the position of the stomach.Conclusions. The basic requirements and approaches to the development of gastroretentive drug delivery systems and examples to obtain tablets that can be kept for a long time in the stomach are considered.References1. Garg R. Progress in sontrolled gastroretentive delivery systems / R Garg, GD Gupta // Tropical Journal of Pharmaceutical Research. – 2008. - №7(3). – R.1055-1066. 2. Review on gastroretentive drug delivery system / A. Badoni I, A. Ojha, G. Gnanarajan et al. // The pharma innovation. – 2012. - Vol.1, № 8. – R.32-42.3. AReview on gastroretentive drug delivery system / Pranav Joshi, Priyank Patel,Hiren Modi et al. // International Journal of Pharmaceutical Science and Bioscientific Research. – 2012. – Vol. 2, Issue 3. – P.123-128.4. Streubel A. 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