73 research outputs found
Hickam's Dictum prevails: navigating the maze of dual pathology in HIV
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ABOUT THE AUTHORS
Rafiq Shajahan
Medical Department, Hospital Kuala Lumpur
Imran Thoulath
Cardiology Department, Institut Jantung Negara
Malaysia
Rashida Safiuddin
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Ahmad Zuhri Shin Abd Halim
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Rozilah Ishak
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Suria Hayati Md Pauzi
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Nurismah Md Isa
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Wei Hao Kok
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Najma Kori
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Ummu Afeera Zainulabid
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Petrick Periyasamy
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
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Home > 2023 > Shajahan
Hickam's Dictum Prevails: Navigating the Maze of Dual Pathology in HIV
Rafiq Shajahan, Imran Thoulath, Rashida Safiuddin, Ahmad Zuhri Shin Abd Halim, Rozilah Ishak, Suria Hayati Md Pauzi, Nurismah Md Isa, Wei Hao Kok, Najma Kori, Ummu Afeera Zainulabid, Petrick Periyasamy
Abstract
In the realm of HIV, considering various causes for clinical presentations is crucial. This case report reveals the exceptional coexistence of advanced neuroendocrine tumor and Burkitt's lymphoma, an infrequently reported combination in an individual with HIV. Emphasizing Hickam's Dictum, which promotes comprehensive exploration of multiple possibilities, rather than settling for a single diagnosis (Occam's razor), we present the intriguing journey of a 44- year-old man with HIV and hepatitis B co-infection. The patient, diagnosed with HIV and hepatitis B in 2017, discontinued antiretroviral therapy and presented to the emergency department with breathlessness. He experienced fever, night sweats, chronic diarrhoea, and a significant weight loss of 15 kg over six months. Physical examination revealed flushed cheeks, hepatomegaly, and other alarming signs. Initial treatment focused on disseminated tuberculosis, but further investigations unveiled heart failure and a pancreatic lesion. The clinical picture suggested neuroendocrine tumor and carcinoid syndrome, supported by elevated serum chromogranin levels. A colonoscopy ruled out gastrointestinal involvement but surprisingly revealed Burkitt's lymphoma. Tragically, the patient succumbed to a carcinoid crisis. This case highlights the importance of considering multiple differentials in HIV-infected individuals, as illustrated by the convergence of neuroendocrine tumor and Burkitt's lymphoma. Previous case reports suggest an unusual link between carcinoid tumours and lymphoreticular malignancies. Neuroendocrine hormones may influence the proliferation and mitogenesis of lymphoid cells that may develop into diseases. Vigilance in recognizing and understanding dual pathology can aid in reducing mortality. Further research is needed to explore potential connections between these rare malignancies
Biosensor for the detection of Listeria monocytogenes: emerging trends
No full textThe early detection of Listeria monocytogenes (L. monocytogenes) and understanding the disease burden is of paramount interest. The failure to detect pathogenic bacteria in the food industry may have terrible consequences, and poses deleterious effects on human health. Therefore, integration of methods to detect and trace the route of pathogens along the entire food supply network might facilitate elucidation of the main contamination sources. Recent research interest has been oriented towards the development of rapid and affordable pathogen detection tools/techniques. An innovative and new approach like biosensors has been quite promising in revealing the foodborne pathogens. In spite of the existing knowledge, advanced research is still needed to substantiate the expeditious nature and sensitivity of biosensors for rapid and in situ analysis of foodborne pathogens. This review summarizes recent developments in optical, piezoelectric, cell-based, and electrochemical biosensors for Listeria sp. detection in clinical diagnostics, food analysis, and environmental monitoring, and also lists their drawbacks and advantages
Hemangioma of Tongue with Abrupt Growth Onset: A Rare Case Report
No full textHemangiomas of the oral cavity are uncommon but have a predilection for the tongue. Although the majority of lingual hemangomas are superficial, certain lesions can affect the deep tongue or even the entire tongue. They're called hamartomas rather than genuine neoplasms. Author presents a case of haemangioma of the anterior 2/3rd of the tongue involving both ventral and dorsal aspects, and ascertaining the diagnostic evaluation and emphasizing the role of color doppler ultrasonography and contrast enhanced magnetic resonance imaging in unrevealing the diagnostic dilemma of the lesion, and further helping in deciding the level of the management. This Study presents a relatively rare and unusual case of haemangioma of tongue with abrupt onset of growth
Dekonstruksi Pemahaman Surah Al-Qashash Ayat 56 Terhadap Justifikasi Kekafiran Abu Thalib
No full textDeconstruction of Understanding of Surah Al-Qashash Verse 56 Against the Justification of Abu Talib's disbeliefThis paper discusses the deconstruction of the interpretation of the justification of the mufassirin scholars regarding the disbelief of Abu Thalib as the uncle of the Prophet Muhammad in understanding surah al-Qashas verse 56. The author approaches by understanding the tafsir al-ma'tsur. This method is by understanding the verse before surah Al-Qashas verse 56 and after the verse, when the verse already has the same understanding relationship, then looks for verses that have the same topic, then looks for hadiths that have a relevant relationship to the topic being discussed. , so that we arrive at the analysis and the conclusion that the word "ahbabka" in the verse is not referred to as Abu Thalib, but to the uncle of the Prophet. another. So it can be concluded that Abu Thalib lived in a state of faith and died in a state of fait
Effective removal of methylene blue using nanoscale manganese oxide rods and spheres derived from different precursors of manganese
No full textNanoscale manganese oxide with different morphologies were developed at room temperature using different precursor salts (potassium permanganate and manganese sulfate). The obtained nanoscale morphologies, i.e., rod and sphere-shaped were characterized using BET surface area analyzer, SEM, TEM, and XRD. The manganese oxide possessed the rod and sphere-like morphologies with different pore structures. The adsorption of methylene blue on mesoporous manganese oxide followed the pseudo-second-order kinetics and best fitted with the Freundlich adsorption isotherm model with a removal capacity of 2914 mg g−1. The effect of irradiation time on degradation efficiency was also examined, which followed the first-order kinetics with a degradation efficiency of 93.12%. Furthermore, the recycling studies revealed that the spherical manganese oxide retained over 90% of the photodegradation efficiency after three cycles of methylene blue degradation, which proves its stability for practical applications. Therefore, mesoporous manganese oxide with significant adsorption and remarkable photodegradation capability can provide a way forward to fine-tune the material's properties for effective environmental remediation.</p
Trees, Shrubs and Grasses for Saltlands: an Annotated Bibliography
Get PDFResource /Energy Economics and Policy,
Scientometric Analysis for Cross-Laminated Timber in the Context of Construction 4.0
No full textCross-laminated timber (CLT) has been one of the principal materials in mass timber construction, and now it is possible to find mid-rise and high-rise projects around the globe. This study makes a scientometric review comparison between CLT and the impact of the fourth industrial revolution (formally known as Industry 4.0) in the construction industry, focusing on worldwide academic publications between 2006 and 2022. The analysis considers keywords, co-author, co-citation, and clustering analysis. This study used 1320 documents, including journals and conference proceedings from the Scopus database, where 753 were for cross-laminated timber and 567 for Industry 4.0. Key researchers, research institutions, journals, publications, citation patterns, and trends are some of the results obtained from the scientometric analysis. Once the knowledge mapping was conducted for both fields, scrutiny of the interconnection of both areas was performed to find possible research gaps from a manufacturing perspective. Among the conclusions, it is logical to say that Industry 4.0 implementation in cross-laminated timber is still in its infancy. One of the most popular technologies impacting construction is the digital twin concept; however, no work is reported for CLT on this topic. Additionally, digital automation is a necessity in any research practice, and the use of industrial robots is shown to be an essential asset for CLT as these robots can handle complex shapes
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