1,724 research outputs found
'Comments' on Charles Stephenson's 'Process of Community' and Ronald Foresta's 'Evolution of the Modern Urban Core' - from the 8th NJ History Symposium
No full textThis comments paper by Seth M. Scheiner, an Associate Professor of History at Rutgers University, is from 'New Jersey's Ethnic Heritage: Papers Presented at the Eighth Annual New Jersey History Symposium, December 4, 1976.' Scheiner critiques two research papers from the 8th NJ History Symposium: Charles Stephenson's 'Process of Community' and Ronald Foresta's 'Evolution of the Modern Urban Core.' He also provides additional research related to urban models, demographical statistics, and immigration patterns in New Jersey
Humanism, Cosmopolitanism, and the Search for Belonging: A Thematic Analysis of the Select Works of Vikram Seth
No full textVikram Seth holds a unique status in modern Indian English literature as an author whose work surpasses strict national, cultural, and genre limitations. Most renowned for his masterwork A Suitable Boy, part of Seth\u27s literary oeuvre—comprising poetry, verse novels, travel writing, and prose fiction—demonstrates a consistent exploration of humanism, cultural plurality, love, identity, tradition, modernity, and ethical coexistence. This article conducts a thorough thematic analysis of Vikram Seth\u27s principal works, including A Suitable Boy, The Golden Gate, From Heaven Lake, An Equal Music, and his poetry collections. The study contends that Seth\u27s writing transcends mere formal or biographical analysis, revealing a subtle yet significant ethical perspective that emphasizes individual agency, emotional moderation, and secular humanistic principles within a postcolonial, globalized context. The study examines how Seth navigates the conflicts between tradition and change, personal desire and social obligation, nationalism and cosmopolitanism, as well as art and life. The essay ultimately portrays Vikram Seth as a writer who challenges prevailing ideological extremes—nationalist, colonial, or global—by restoring the dignity of ordinary human experience and the potential for harmony amidst diversity
Exploring adaptation with evolutionary activity plots
No full textEvolutionary activity statistics and their visualization are introduced, and their motivation is explained. Examples of their use are described, and their strengths and limitations are discussed. References to more extensive or general accounts of these techniques are provided
Hydroamination of terminal allylic imines, allylic amines, and internal and terminal homoallylic amines: Regioselective and regiodivergent transformations
No full textC–N bonds are ubiquitous in organic chemistry. Mild methods that allow for the direct formation of this motif from readily accessible functional groups would represent a powerful advance in organic synthesis. The intermolecular hydroamination of alkenes and amines represents a novel approach towards these disconnections from readily accessible functional groups. This transformation can streamline the synthesis of complex molecules and often allows access to two regioisomers (Markovnikov and anti-Markovnikov) from one starting material.
1,2-diamines are a common motif in many organic molecules. However, their synthesis often involves a lengthy, multi-step synthetic sequence. We report the Rh- and Ir-catalyzed addition of secondary cyclic, secondary acyclic, and primary acyclic (both aryl and aliphatic) amines to allyl amine. This transformation is highly chemoselective, regioselective, functional group tolerant, and can be used to form trans-diamines with excellent selectivity. Future directions for this method, including anti-Markovnikov and/or asymmetric hydroamination are discussed.
The anti-Markovnikov hydroamination of aliphatic alkenes is a significant challenge for organometallic chemists. These products are typically formed via formal hydroamination. We report the Rh-catalyzed anti-Markovnikov selective hydroamination of homoallylic amines to form 1,4-diamines with electron rich secondary cyclic and acyclic amine nucleophiles. This transformation is tolerant of a variety of substituents on the homoallylic amine and mechanistic studies on these substrates are summarized.
The regiodivergent functionalization of a substrate is a powerful method in organic chemistry; in the hydroamination literature, this transformation typically requires activated alkenes (allenes, dienes, etc.) and is limited in scope. The regiodivergent intermolecular hydroamination of homoallylic amines to selectively form either 1,3- or 1,4-diamines is disclosed. This method features both novel aryl amine nucleophiles and catalysts to form the desired product. This transformation is demonstrated on both terminal and internal alkenes and future directions are proposed.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-12-01The student, Seth Ensign, accepted the attached license on 2017-09-01 at 07:03.The student, Seth Ensign, submitted this Dissertation for approval on 2017-09-01 at 07:07.This Dissertation was approved for publication on 2017-09-14 at 13:12.DSpace SAF Submission Ingestion Package generated from Vireo submission #11629 on 2018-03-13 at 10:32:34Made available in DSpace on 2018-03-13T17:29:02Z (GMT). No. of bitstreams: 5
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Robot modeling and control / Mark W. Spong, Seth Hutchinson, M. Vidyasagar.
No full textIncludes bibliographical references (pages 459-470) and index.478 pages :{09}Introduction -- Rigid motions and homogeneous transformations -- Forward and inverse kinematics -- Velocity kinematics-The Jacobian -- Path and trajectory planning -- Dynamics -- Independent joint control -- Multivariable control -- Force control -- Geometric non-linear control -- Computer vision -- Vision-based control -- Appendix A Trigonometry -- Appendix B Linear algebra -- Appendix C Dynamical systems -- Appendix D Lyapunov stability -- Index
Discovery of an optical counterpart to the hyperluminous X-ray source in ESO 243-49
No full textThe existence of black holes of masses similar to 10(2)-10(5)M(circle dot) has important implications for the formation and evolution of star clusters and supermassive black holes. One of the strongest candidates to date is the hyperluminous X-ray source (HLX1), possibly located in the S0- a galaxy ESO 243-49, but the lack of an identifiable optical counterpart had hampered its interpretation. Using the Magellan telescope, we have discovered an unresolved optical source with R = 23.80 +/- 0.25 mag and V = 24.5 +/- 0.3 mag within HLX1's positional error circle. This implies an average X-ray/optical flux ratio similar to 500. Taking the same distance as ESO 243-49, we obtain an intrinsic brightness M-R = -11.0 +/- 0.3 mag, comparable to that of a massive globular cluster. Alternatively, the optical source is consistent with a main-sequence M star in the Galactic halo (for example an M4.4 star at approximate to 2.5 kpc). We also examined the properties of ESO 243-49 by combining Swift/Ultraviolet/Optical Telescope (UVOT) observations with stellar population modelling. We found that the overall emission is dominated by a similar to 5-Gyr-old stellar population, but the UV emission at approximate to 2000 angstrom is mostly due to ongoing star formation at a rate of similar to 0.03M(circle dot) yr(-1). The UV emission is more intense (at least a 9 sigma enhancement above the mean) north-east of the nucleus, in the same quadrant as HLX1. With the combined optical and X-ray measurements, we put constraints on the nature of HLX1. We rule out a foreground star and a background AGN. Two alternative scenarios are still viable. HLX1 could be an accreting intermediate mass black hole in a star cluster, which may itself be the stripped nucleus of a dwarf galaxy that passed through ESO 243-49, an event which might have caused the current episode of star formation. Or, it could be a neutron star in the Galactic halo, accreting from an M4-M5 donor star
Cognitive status in patients hospitalized with acute decompensated heart failure
No full textSeth N. Levin participated in this study as a medical student as part of the Senior Scholars research program at the University of Massachusetts Medical School.
Co-author Alexandra M. Hajduk is a doctoral student in the Clinical and Population Health Research Program in the Graduate School of Biomedical Sciences (GSBS) at UMass Medical School.BACKGROUND: Cognitive impairment is highly prevalent in patients with heart failure and is associated with adverse outcomes. However, whether specific cognitive abilities (eg, memory vs executive function) are impaired in heart failure has not been fully examined. We investigated the prevalence of impairment in 3 cognitive domains in patients hospitalized with acute decompensated heart failure (ADHF) and the associations of impairment with demographic and clinical characteristics. METHODS: The sample included 744 patients hospitalized with ADHF (mean age 72 years, 46% female) at 5 medical centers. Impairment was assessed in 3 cognitive domains (memory, processing speed, executive function) using standardized measures. Demographic and clinical characteristics were obtained from a structured interview and medical record review. RESULTS: A total of 593 (80%) of 744 patients were impaired in at least 1 cognitive domain; 32%, 31%, and 17% of patients were impaired in 1, 2, or all 3 cognitive domains, respectively. Patients impaired in more than 1 cognitive domain were significantly older, had less formal education, and had more noncardiac comorbidities (all P values < .05). In multivariable adjusted analyses, patients with older age and lower education had higher odds of impairment in 2 or more cognitive domains. Depressed patients had twice the odds of being impaired in all 3 cognitive domains (odds ratio 1.98, 95% CI 1.08-3.64). CONCLUSION: Impairments in executive function, processing speed, and memory are common among patients hospitalized for ADHF. Recognition of these prevalent cognitive deficits is critical for the clinical management of these high-risk patients.Clinical and Population Health Researc
Physical activity for the brain, but for whom? An individual difference investigation of the FITKids clinical trial on cognitive control and ERPs in children
No full textThe present dissertation examined the interaction of cardiorespiratory fitness, socioeconomic status (SES), and sex to cognitive control outcomes associated with a 9-month physical activity intervention (FITKids clinical trial) in preadolescent children. This was accomplished by randomizing three hundred eighty-four children into an afterschool physical activity intervention or a wait-list control group. All participants at pre- and post-test completed a cardiorespiratory fitness assessment as well as a modified flanker task while event-related potentials (ERP) were collected. Pre-test cardiorespiratory fitness results revealed insufficient sample size for higher-fit children. Thus, fitness was utilized as a matching variable with one hundred seventy-two participants (n = 86 treatment; n = 86 wait-list) successfully matched across treatment, SES, and sex. Results demonstrated that a 9-month physical activity intervention significantly improved flanker accuracy and post-error accuracy for all children in the intervention compared to the wait-list group, regardless of SES or sex. Additionally, ERP findings revealed sexual dimorphic facilitation in error processing networks and conflict adaptation such that only females in the treatment group demonstrated decreased N2 amplitude while only females in the wait-list group demonstrated increase ERN amplitude from pre- to post-test. Together, these results have considerable implications for promoting organized physical activity interventions for improving cognitive health, regardless of SES or sex, with further implications for sexual selective benefits to performance monitoring brain patterns in preadolescent females.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2018-05-01The student, Eric Drollette, accepted the attached license on 2016-04-08 at 13:50.The student, Eric Drollette, submitted this Dissertation for approval on 2016-04-08 at 14:03.This Dissertation was approved for publication on 2016-04-11 at 13:45.DSpace SAF Submission Ingestion Package generated from Vireo submission #9170 on 2016-07-07 at 13:48:58Made available in DSpace on 2016-07-07T20:27:11Z (GMT). No. of bitstreams: 3
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Treatment of Atrophic Acne Scarring with Fractional Microplasma Radiofrequency: A Multicentric Experience
No full textBackground: Atrophic scarring is a severe form-disfiguring sequela of acne, which can lead to negative effect on patients' life. Fractional microplasma radiofrequency (RF) has emerged as a promising modality, leveraging dermal fibroblast remodeling to enhance aesthetic results for scars and hyperpigmentation. This study evaluates the efficacy and safety of high-power fractional microplasma RF for atrophic acne scars, considering patient tolerance to procedural discomfort. Methods: In this prospective study, 95 Chinese patients with atrophic facial acne scars underwent three sessions of fractional microplasma RF treatment, with assessments at 1, 3, and 6 months post-treatment. Patients were categorized based on treatment power: Group A (50-70 W) and Group B (70-85 W). Efficacy was determined by three independent dermatologists using digital photographs and Echelle d'Evaluation Clinique des Cicatrices d'Acn & eacute; (ECCA) scores, and patient-reported outcomes gauged satisfaction levels. Results: Eighty-six patients completed the study. Significant improvements were observed, with a reduction in ECCA scores from 107.21 to 42.27 (P<0.05), demonstrating notable scar amelioration across both groups, albeit with a superior outcome in Group B. All patients experienced transient side effects such as pain, erythema, and edema, deemed tolerable with no long-term adverse effects reported. The treatment was well-received, with high satisfaction rates, underscoring its efficacy and acceptable safety profile. Conclusion: Fractional microplasma RF therapy, particularly at higher power settings, is an effective and safe option for treating atrophic acne scars, offering significant aesthetic improvement with manageable discomfort. This modality presents a valuable addition to acne scar management strategies, especially for patients with darker skin tones seeking minimal downtime and reduced risk of hyperpigmentation. (c) 2024 The Author(s). Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/
Author Correction: Dental anomaly detection using intraoral photos via deep learning (Scientific Reports, (2022), 12, 1, (11577), 10.1038/s41598-022-15788-1)
No full textIn the original version of this Article Ronilo Ragodos, Tong Wang and Brian J. Howe were omitted as equally contributing authors. Tong Wang was omitted as an additional corresponding author. Correspondence and requests for materials should also be addressed to [email protected]. In addition, the Author Contributions section in this Article was incorrect.Fil: Ragodos, Ronilo. University of Iowa; Estados UnidosFil: Wang, Tong. University of Iowa; Estados UnidosFil: Padilla, Carmencita. University of the Philippines; FilipinasFil: Hecht, Jacqueline T.. University of Texas; Estados UnidosFil: Poletta, Fernando Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Orioli, Ieda Maria. Universidade Federal do Rio de Janeiro; BrasilFil: Buxó, Carmen J.. Universidad de Puerto Rico; Puerto RicoFil: Butali, Azeez. University of Iowa; Estados UnidosFil: Valencia Ramirez, Consuelo. Clinica Noel; ColombiaFil: Restrepo Muñeton, Claudia. Clinica Noel; ColombiaFil: Wehby, George. University of Iowa; Estados UnidosFil: Weinberg, Seth M.. University of Pittsburgh; Estados Unidos. University of Pittsburgh at Johnstown; Estados UnidosFil: Marazita, Mary L.. University of Pittsburgh at Johnstown; Estados Unidos. University of Pittsburgh; Estados UnidosFil: Moreno Uribe, Lina M.. University of Iowa; Estados UnidosFil: Howe, Brian J.. University of Iowa; Estados Unido
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