7 research outputs found
Treatment of large xanthelasma palpebrarums with full-thickness skin grafts obtained by blepharoplasty
No full textPubMed: 23673303Purpose: The treatment of large xanthelasma palpebrarum cases in patients whose lesions could not be closed primarily is reported. All lesions were repaired with full-thickness skin grafts obtained by blepharoplasty of the same upper eyelid. Patient satisfaction, complications, and recurrence rates were investigated. Methods: Sixteen patients were treated between 2007 and 2012. Bilateral upper eyelids were involved in all patients. Twenty-six large xanthelasma palpebrarum lesions were treated using this method. All lesions were located in the medial canthus of the upper eyelid. Results: The patients were followed up for 6 months to 5 years (mean 3 years). No patients developed complications or required revision surgery. All patients had normally positioned upper eyelids and were satisfied with the aesthetic outcome. Two patients had mild hyperpigmentation at the graft site. Conclusions: The results of this study suggest that large xanthelasma palpebrarum defects that are not primarily closed after excision should be repaired with full-thickness skin grafts harvested from the lateral aspect of the same upper eyelid. Moreover, good patient satisfaction can be achieved when blepharoplasty of the upper eyelid is performed concurrently in patients who are middleaged or older. © 2013 Canadian Dermatology Association
The Efficacy of Ankaferd Blood Stopper in Heparin‐Induced Hemostatic Abnormality in a Rat Epistaxis Model
No full textEccrine porocarcinoma arising from preexisting eccrine poroma of the scalp after radiotherapy for cervical cancer
No full text
Recommended from our members
Eccrine porocarcinoma arising from preexisting eccrine poroma of the scalp after radiotherapy for cervical cancer
No full textImprovement of the Strength of Ankara Clay with Self-cementing High Alkaline Fly Ash
No full textAbstractTurkey's plants are fired by lignite, producing class C fly ash containing a high percentage of lime. Sulphate and alkali levels are also higher in class C fly ashes. Therefore, fly ash is, commonly, unsuitable as an additive in cement or concrete in Turkey. In this study, highly alkaline fly ash obtained from the Yenikoy thermal power plants is combined with soil samples in different proportions (5%, 15%, and 25%) and changes in the geomechanical properties of Ankara clay were investigated. The effect of curing time on the physical-mechanical properties of the fly ash mixed soil samples was also analyzed. Free swelling index values showed a decrease of 92.6%. The California bearing ratio has seen a more drastic increase in value (68.7 times for 25% fly ash mix)
Differential loss of PRUNE2 in colorectal adenocarcinoma tissues
No full textColorectal cancer is of the most prevalent and deadliest cancer in the world. Cumulative evidence suggests that PRUNE is a tumor suppressor gene and plays a significant role in the development and progression of human cancers. However, its role during colorectal cancer development remains elusive. In the present study, we aimed to determine the role of PRUNE2 and its diagnostic significance in colorectal cancer. A total of 70 patients with colorectal cancer and 30 control subjects were included in the present study. All patients were confirmed to be colorectal adenocarcinoma. PRUNE2, P53, and PCNA immunoreactivity of patients were determined using standard immunohistochemistry staining techniques. Notably, PRUNE2 was identified to be significantly downregulated in colorectal cancer patients compared to the control group (p < 0.0001). Almost no immunoreactivity was observed in tumor samples compared to healthy colon tissues, where significant immunoreactivity was observed. Also, both P53 and PCNA were significantly higher in patients with colorectal cancer (p < 0.0001). Overall, our results suggest that PRUNE is a reliable and robust biomarker for the differential diagnosis of colorectal cancer and can be used for future diagnostic applications together with other immunological biomarkers such as PCNA. © The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature 2025
