1,720,955 research outputs found
Sustainable Solution to Antibiotic Resistance: Pavetta indica-Based Nanomedicine
Full text linkThe escalating global health crisis, characterized by the emergence of antimicrobial-resistant pathogens, necessitates innovative strategies. This study explores the potential of Pavetta indica, a previously underutilized plant, as a multifaceted resource for addressing this critical challenge. A comprehensive phytochemical investigation unveiled a rich repertoire of bioactive compounds within P. indica, including essential metabolites Moisture (9.14%), Crude Protein (10.93%), and Crude Fiber (15.46%). Additionally, significant levels of Calcium, Phosphorus, and Ether Extract were identified, suggesting its potential contribution to a balanced diet and a diverse array of secondary metabolites identified through GC-MS analysis identified diverse bioactive compounds including Dodecanoic acid, Lupeol, and β-D-Glucopyranose among others, highlighting its potential health benefits and paving the way for further research on specific bioactivities. P. indica extract exhibited concentration-dependent ABTS and DPPH scavenging activities, comparable to ascorbic acid. This underscores its potential as a natural antioxidant source to combat oxidative stress-related diseases. Leveraging the bio-reducing capabilities of P. indica extract, we embarked on the green synthesis of silver nanoparticles. P. indica extract successfully synthesized silver nanoparticles, confirmed by UV-Vis spectroscopy (SPR band at 420 nm) and TEM (spherical particles, 25-50 nm). These nanoparticles showed potent antimicrobial activity against Bacillus subtilis, E. coli, and Pseudomonas aeruginosa, comparable to Gentamicin. The synthesized silver nanoparticles demonstrated concentration-dependent antifungal activity against Candida albicans, Aspergillus fumigatus, and Sporothrix schenckii, suggesting their potential as effective antifungal agents. Our findings underscore the significance of exploring underutilized plant resources for developing innovative solutions to pressing global health challenges. By integrating phytochemistry, nanotechnology, and microbiology, this research offers a promising approach to combating antimicrobial resistance. The study\u27s outcomes lay the groundwork for future investigations into the underlying mechanisms of antimicrobial action, optimization of nanoparticle properties, and preclinical evaluation of their therapeutic efficacy
Unveiling the Ancient Wisdom: Antibacterial and Antifungal Properties of Pavetta indica
Full text linkThis study investigated the antibacterial and antifungal properties of Pavetta indica leaves using an ethanolic extract (PI). The agar well diffusion method revealed dose-dependent inhibition zones against various bacterial and fungal strains. Notably, the extract demonstrated promising antifungal activity against Cryptococcus neoformans, comparable to the positive control (Amphotericin B) for fungal activity. All tested bacterial strains (E. coli, Streptococcus faecalis, Bacillus subtilis, Pseudomonas aeruginosa) and fungal strains (Candida albicans, Aspergillus fumigatus, Sporothrix schenckii) exhibited susceptibility to PI, with inhibition zones increasing proportionally with extract concentration. Overall, this study suggests that P. indica leaves possess promising potential as a natural source of broad-spectrum antimicrobial and antifungal agents
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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