1,721,213 research outputs found
Dynamic Protein Affinity Selection Mass Spectrometry
Get PDFIrth, H. [Promotor]Lingeman, H. [Copromotor]Kool, J. [Copromotor
Advanced bioactivity screening analytics for rapid identification of environmental toxicants
Get PDFSomsen, G.W. [Promotor]Kool, J. [Copromotor
Miniaturized bioactivity screening of complex samples
Get PDFIrth, H. [Promotor]Niessen, W.M.A. [Promotor]Kool, J. [Copromotor
High-resolution screening of metabolite-like lead libraries
Get PDFIrth, H. [Promotor]Niessen, W.M.A. [Promotor]Honing, M. [Promotor]Kool, J. [Copromotor
Innovative analytical methodologies for bioactivity/bioaffinity profiling of complex mixtures
Get PDFNiessen, W.M.A. [Promotor]Smit, M.J. [Promotor]Somsen, G.W. [Promotor]Kool, J. [Copromotor
High resolution screening analytics for identification of natural bioactives
Get PDFSomsen, G.W. [Promotor]Smit, A.B. [Promotor]Kool, J. [Copromotor
Methodologies for Effect-Directed Analysis: applications in environmental chemistry, food quality assessment and drug discovery
No full text
A Bayesian hindcasting method of levee failures applied to the Breitenhagen slope failure
Get PDFHindcasting of past levee failures enhances insights in the performance and vulnerability of levees. The scarcity of field evidence makes identifying the cause(s) of failure difficult. Under these circumstances, multiple scenarios and model choices are possible to characterise and to model the failure. This paper shows how probabilistic Bayesian techniques advance the procedure of hindcasting of levee failures. In the developed approach, a-priori levee information, and failure observations are systematically taken into account to determine the most likely scenario and the most representative model choices to characterise the failure most accurately. Observations, such as the slip surface, are taken into account in the probability estimates. The levee failure near Breitenhagen, Germany (2013) is used as a case study. The levee failed during river floods due the instability of the landside slope. The levee failure was most likely triggered by locally weak soil conditions and unexpected high water pressures due a connection between a pond on the riverside of the levee and the aquifer. These conditions were likely caused by the occurrence of a previous breach at this location. The approach developed in this paper is expected to support a more systematic and objective method of analysis of other levee failures
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
