199,921 research outputs found
Variants from "The role of deleterious substitutions in crop genomes"
No full textThere are two gzipped VCF (variant call format) files with variant calls for barley and soybean. A total of 652,797 SNPs were identified in the barley lines, which consisted of 13 cultivars and 2 wild accessions. For soybean, 7 cultivars and 1 wild accession were used, and 586,102 SNPs were called. Whether a variant is deleterious or not was determined using SIFT (http://sift.jcvi.org/), PolyPhen2 (http://genetics.bwh.harvard.edu/pph2/), and a likelihood ratio test of sequence conservation. Raw reads are available through the SRA accession numbers in Table S1 of Kono et al. 2016. The code used for this research, BAD_Mutations, is open source and freely available at https://github.com/MorrellLAB/BAD_Mutations.SNP calls in protein coding regions were obtained from 15 barley and 8 soybean lines. Non synonymous SNPs were predicted to be deleterious or not using three approaches.USDA NIFA National Needs Fellowship (Appropriation No. 5430-21000-006-00D)MnDrive 2014 Food Security FellowshipMinnesota Agricultural Experiment Station Variety Development fundUnited Soybean BoardU.S. NSF Plant Genome Program (BDI-1339393)Kono, Thomas J Y; Fu, Fengli; Mohammadi, Mohsen; Hoffman, Paul J; Liu, Chaochih; Stupar, Robert M; Smith, Kevin P; Tiffin, Peter; Fay, Justin C; Morrell, Peter L. (2016). Variants from "The role of deleterious substitutions in crop genomes". Retrieved from the University Digital Conservancy, http://doi.org/10.13020/D65C7D
Vapor mixture two phase flow analysis in waterhammer by upstream finite difference method
No full textY. Kono, A.R. Simpson and M. Watanab
Viscosity of alkaline basalts at high pressure: constraints on the pre-eruptive system of Campi Flegrei (Italy)
No full textThe Campi Flegrei Volcanic District (CFVD) includes the Campi Flegrei caldera, the islands of Procida
and Ischia, and it is among the most dangerous volcanic systems of the world. The volcanic activity that has
characterized the recent eruptive history of the CFVD includes both effusive and hydromagmatic eruptions
that resulted in a variety of igneous products from alkaline basalts to trachytes. Among CFVD products,
basaltic lava fragments dispersed in the hydromagmatic tuff of the Solchiaro eruption (Procida island) result
to be representative of near-primary melts on the basis of their geochemical and isotopical signatures. The
knowledge of the viscosity of primitive magmas at high pressure and temperature is needed to model their
mobility and ascent rate. These variables allow us to predict the potential volcanic activity at surface. In
this study, we investigated the viscosity and melt structure of APR16 alkaline basalt, a lava fragment of
the Solchiaro eruption. The anhydrous glassy starting material was prepared at Bayerisches Geoinstitut by
using a gas-mixing furnace, by melting the APR16 rock powder at 1400 °C for 15 minutes at atmospheric
pressure and oxygen fugacity buffered at Nickel-Nickel Oxide level using a CO/CO2 gas mixture. Experiments
were performed at pressure between 0.7 and 2.3 GPa and temperatures of 1200 °C-1700 °C using the Paris-
Edinburgh press combined with synchrotron X-ray technique at beamline 16-BM-B (HPCAT) of the Advanced
Photon Source (Argonne National Laboratory, Illinois, USA). Viscosity measurements were conducted with
the falling sphere technique. The falling velocity of the platinum probing sphere was measured at each run
by ultrafast X-ray radiography using a high-speed camera at 500 frames per second as recording rate. The
viscosity was, then, calculated from the Stokes’ equation including the correction factors for the effect of the
wall and the end effect (Kono et al., 2014). Structural measurements of the liquid at 1700 °C and 2.3 GPa were
also performed using multi-angle (2θ angle between 3° to 35°) energy dispersive X-ray diffraction technique.
Preliminary results show the viscosity increasing from 0.1 to 1 Pa·s as pressure decreases from which an
increase in the polymerization during decompression can be inferred. Our results are used to constrain the
mobility and ascent velocity of primitive alkaline basalts considered to be parental magmas at Campi Flegrei
with important implications for the potential volcanic hazard of the area.
Kono, Y., Park, C., Kenney-Benson, C., Shen, G. & Wang, Y. (2014): Toward comprehensive studies of liquids at high
pressures and high temperatures: Combined structure, elastic wave velocity, and viscosity measurements in the Paris-
Edinburgh cell. Phys. Earth Planet. Inter., 228, 269-280
High resolution pulsed spectroscopic source using an injection-seeded optical parametric oscillator/amplifier system
No full textWe have developed a narrowband tunable injection-seeded, pulsed optical parametric oscillator/amplifier system. Using optical heterodyne and nonlinear-optical spectroscopic techniques, we measure a near Fourier transform limited output with a controllable frequency chirp of <10 MHz.K.G.H. Baldwin, M. Kono, B. J. Orr, Y. He and R. T. Whit
A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo
No full textIn vivo imaging has revolutionized understanding of the spatiotemporal complexity that subserves the generation of successful effector and regulatory immune responses. Until now, invasive surgery has been required for microscopic access to lymph nodes (LNs), making repeated imaging of the same animal impractical and potentially affecting lymphocyte behavior. To allow longitudinal in vivo imaging, we conceived the novel approach of transplanting LNs into
the mouse ear pinna. Transplanted LNs maintain the structural and cellular organization of conventional secondary lymphoid organs. They participate in lymphocyte
recirculation and exhibit the capacity to receive and respond to local antigenic challenge. The same LN could be repeatedly imaged through time without the requirement for surgical exposure, and the dynamic behavior of the cells within the transplanted LN could be characterized. Crucially, the use of blood vessels as fiducial markers also allowed precise re-registration of the same regions for
longitudinal imaging. Thus, we provide the first demonstration of a method for repeated, noninvasive, in vivo imaging of lymphocyte behavior
Crohn's disease and postoperative recurrence. The role of anastomotic configurations and the kono-s anastomosis.
No full textBACKGROUND: The observation that in more than 90% of Crohn's disease patients the postoperative recurrences are located in the pre-anastomotic tract leads us to suppose that the anastomosis would play a role in the appearance of recurrences.
AIM AND METHODS: To focus the role of different anastomotic configurations in the incidence of recurrences, the Authors have conducted a review of the literature of the last two decades and have revised critically their experience.
RESULTS: The rate of recurrences seem to be lower in patients in whom the anastomotic configuration is such as to present a wide lumen; it seems that they are lower after stapled side-to-side anastomosis. The Kono-S anastomosis, recently introduced technique, seems to offer better results.
CONCLUSIONS: The role of the various types of anastomosis remains uncertain. Further large-scale controlled trials with long term follow-up are needed
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Control of frequency chirp in nanosecond-pulsed laser spectroscopy. 1. Optical-heterodyne chirp analysis techniques
No full textRichard T. White, Yabai He, Brian J. Orr, Mitsuhiko Kono, and K. G. H. Baldwi
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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