41 research outputs found

    Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study.

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    BACKGROUND: Human papillomaviruses are the most common sexually transmitted infections, and genital warts, caused by HPV-6 and 11, entail considerable morbidity and cost. The natural history of genital warts in relation to HIV-1 infection has not been described in African women. We examined risk factors for genital warts in a cohort of high-risk women in Burkina Faso, in order to further describe their epidemiology. METHODS: A prospective study of 765 high-risk women who were followed at 4-monthly intervals for 27 months in Burkina Faso. Logistic and Cox regression were used to identify factors associated with prevalent, incident and persistent genital warts, including HIV-1 serostatus, CD4+ count, and concurrent sexually transmitted infections. In a subset of 306 women, cervical HPV DNA was tested at enrollment. RESULTS: Genital wart prevalence at baseline was 1.6% (8/492) among HIV-uninfected and 7.0% (19/273) among HIV-1 seropositive women. Forty women (5.2%) experienced at least one incident GW episode. Incidence was 1.1 per 100 person-years among HIV-uninfected women, 7.4 per 100 person-years among HIV-1 seropositive women with a nadir CD4+ count >200 cells/μL and 14.6 per 100 person-years among HIV-1 seropositive women with a nadir CD4+ count ≤ 200 cells/μL. Incident genital warts were also associated with concurrent bacterial vaginosis, and genital ulceration. Antiretroviral therapy was not protective against incident or persistent genital warts. Detection of HPV-6 DNA and abnormal cervical cytology were strongly associated with incident genital warts. CONCLUSIONS: Genital warts occur much more frequently among HIV-1 infected women in Africa, particularly among those with low CD4+ counts. Antiretroviral therapy did not reduce the incidence or persistence of genital warts in this population

    Macroeconomics effects of private sector participation in Latin America's infrastructure

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    The authors provide empirical evidence on the impact that private participation in infrastructure has had on key macroeconomic variables in a sample of 21 Latin American countries from 1985-98. Specifically, they look at the effects on GDP per capita, current public expenditures, public investment, and private investment, controlling for country effects and institutional factors. The authors also investigate the relevance of the specific contractual form of private participation contracts on these variables and show differentiated effects according to contract types. The results suggest that: 1) Private sector involvement in utilities and transport have some, but not impressive, positive effects on GDP per capita. 2) There is some degree of crowding-out of private investment resulting from greenfield projects in utilities, and delayed crowding-in from concessions in transport. 3) There is crowding-in of public investment by private participation in utilities, while there is crowding-out by increased private investment in transport. 4) Private participation in utilities decreases recurrent expenditures, while in transport it results in an increase. The net effect on the public sector account is uncertain, but this uncertainty is a major risk. The revelation of this risk may be the main contribution of this paper since it is inconsistent with the fiscal gains expected by many policymakers as they engage in infrastructure privatization programs.Decentralization,Environmental Economics&Policies,Labor Policies,Health Economics&Finance,ICT Policy and Strategies,Health Economics&Finance,Environmental Economics&Policies,ICT Policy and Strategies,Scientific Research&Science Parks,Science Education

    The Africa Growth and Opportunity Act and its rules of origin : generosity undermined?

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    The African Growth and Opportunity Act (AGOA), signed into American law on May 18, 2000, is a major plank of U.S. initiatives toward the African continent. The Act aims broadly at improving economic policymaking in Africa, enabling countries to embrace globalization, and securing durable political and economic stability. As an incentive for Africa to adopt the necessary policy reform, AGOA offers increased preferential access for African exports to the United States. This paper describes the provisions of AGOA and assesses its quantitative impact on African exports, particularly in the apparel sector. Its main conclusions are: 1) AGOA will provide real opportunities to Africa. Even on conservative estimates about Africa's supply response, Africa's non-oil exports could be increased by about 8-11 percent. 2) However, the medium-term gains could have been much greater if AGOA had not imposed certain conditions and not excluded certain items from its coverage. The most important condition is the stringent rule-of-origin, that is, the requirement that exporters source certain inputs from within Africa or the United States. Estimates suggest that the absence of these conditions would have magnified the impact nearly five-fold, resulting in an overall increase in non-oil exports of US0.54billioncomparedwiththeUS0.54 billion compared with the US100-US$140 million increase that is expected in the presence of these restrictions. These restrictions, particularly on apparel, will come at a particularly inopportune time, as Africa will be exposed to competition from other developing countries when the quotas maintained on the latters'exports under the Multi-Fiber Arrangement (MFA) are eliminated. Africa's apparel exports will be lower by over 30 percent with the dismantling of the MFA. If, on the other hand, AGOA had provided unrestricted access, the negative impact of the dismantling could be nearly fully offset.Export Competitiveness,Economic Theory&Research,Trade Policy,Environmental Economics&Policies,Agribusiness&Markets,TF054105-DONOR FUNDED OPERATION ADMINISTRATION FEE INCOME AND EXPENSE ACCOUNT,Economic Theory&Research,Environmental Economics&Policies,Export Competitiveness,Trade Policy

    Financial globalization : unequal blessings

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    The authors present a framework to analyze financial globalization. They argue that financial globalization needs to take into account the relation between money (particularly in its role as store of value), asset and factor price flexibility, and contractual and regulatory institutions. Countries that have the"blessed trinity"(international currency, flexible exchange rate regime, and sound contractual and regulatory environment) can integrate successfully into the world financial markets. But developing countries normally display the"unblessed trinity"(weak currency, fear of floating, and weak institutional framework). The authors define and discuss two alternative avenues (a"dollar trinity"and a"peso trinity") for developing countries to safely embrace international financial integration while the blessed trinity remains beyond reach.Economic Theory&Research,Fiscal&Monetary Policy,Banks&Banking Reform,Payment Systems&Infrastructure,Financial Intermediation,Financial Economics,Macroeconomic Management,Economic Stabilization,Economic Theory&Research,Fiscal&Monetary Policy

    The Devil is in the Details: On the Robust Determinants of Development Aid in G5 Sahel Countries

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    The authors are very grateful to the African Economic Research Consortium (AERC) for the financial support. Thanks to the Chair of thematic research Group C (Finance and Resource Mobilization) Victor Murinde (SOAS, University of London, UK) and our resource persons, including Issouf Soumare (Université Laval, Canada), Alessandra Guariglia (University of Birmingham, UK), Bo Sjö (Linköping University, Sweden) and Prosper Dovonon (Concordia University, Canada) for their insightful comments during the research phase, especially in the collection, analysis and interpretation of data. The lead author would also like to thank the United Nations Economic Commission for Africa (UNECA) for the use of their facilities during the completion of this paper as a Research Fellow with the Macroeconomic Policy Division (MPD) of the UNECA, Addis Ababa, Ethiopia. However, the views expressed are those of the author and do not represent that of the United Nations (UN) or the Central Bank of West African States (BCEAO) and the AERC. Finally, the authors are very grateful to the anonymous reviewers and the Editor-in-Chief of Comparative Economic Studies, whose comments have greatly improved this paper

    Boondoogles and expropriation : rent-sseking and policy distortion when property rights are insecure

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    Most analyses of property rights and economic development point to the negative influence of insecure property rights on private investment. The authors focus instead on the largely unexamined effects of insecure property rights on government policy choices. They identify one significant anomaly-dramatically higher public investment in countries with insecure property rights-and use it to make the following broad claims about insecure property rights; 1) They increase rent-seeking. 2) They may reduce the incentives of governments to use tax revenues for productive purposes, such as public investment. 3) They do so whether one regards the principal problem of insecure property rights as the maintenance of law and order, which government spending can potentially remedy, or as the threat of expropriation by government itself, and therefore not remediable by government spending. The authors present substantial empirical evidence to support these claims.Environmental Economics&Policies,International Terrorism&Counterterrorism,Labor Policies,Economic Theory&Research,Payment Systems&Infrastructure,Environmental Economics&Policies,Economic Theory&Research,National Governance,Public Sector Economics&Finance,Land and Real Estate Development

    The cost of providing combined prevention and treatment services, including ART, to female sex workers in Burkina Faso.

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    BACKGROUND: Female Sex workers (FSW) are important in driving HIV transmission in West Africa. The Yerelon clinic in Burkina Faso has provided combined preventative and therapeutic services, including anti-retroviral therapy (ART), for FSWs since 1998, with evidence suggesting it has decreased HIV prevalence and incidence in this group. No data exists on the costs of such a combined prevention and treatment intervention for FSW. This study aims to determine the mean cost of service provision per patient year for FSWs attending the Yerelon clinic, and identifies differences in costs between patient groups. METHODS: Field-based retrospective cost analyses were undertaken using top-down and bottom-up costing approaches for 2010. Expenditure and service utilisation data was collated from primary sources. Patients were divided into groups according to full-time or occasional sex-work, HIV status and ART duration. Patient specific service use data was extracted. Costs were converted to 2012 US.Sensitivityanalysesconsideredremovalofallresearchcosts,differentdiscountratesanduseofdifferentARTtreatmentregimensandfollowupschedules.RESULTS:Usingthetopdowncostingapproach,themeanannualcostofserviceprovisionforFSWsonoroffARTwasUS. Sensitivity analyses considered removal of all research costs, different discount rates and use of different ART treatment regimens and follow-up schedules. RESULTS: Using the top-down costing approach, the mean annual cost of service provision for FSWs on or off ART was US1098 and US882,respectively.ThecostforFSWsonARTreducedby29882, respectively. The cost for FSWs on ART reduced by 29%, to US781, if all research-related costs were removed and national ART monitoring guidelines were followed. The bottom-up patient-level costing showed the cost of the service varied greatly across patient groups (US505US505-US1117), primarily due to large differences in the costs of different ART regimens. HIV-negative women had the lowest annual cost at US$505. CONCLUSION: Whilst FSWs may require specialised services to optimise their care and hence, the public health benefits, our study shows that the cost of ART provision within a combined prevention and treatment intervention setting is comparable to providing ART to other population groups in Africa
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