470 research outputs found
Medication equivalent dose program in R
No full textCitation: Shinsuke Koike, Yoji Hirano, Shinichiro Nakajima, Kentaro Morita, Medication equivalent dose program in R, Psychiatry and Clinical Neurosciences, 79(6), 356-357, 2025-03-31, https://doi.org/10.1111/pcn.1381
On an expression of neighborhoods around elliptic curves (Mathematical structures of integrable systems and their applications)
No full text"Mathematical structures of integrable systems and their applications". September 5-7, 2018. edited by Shinsuke Iwao. The papers presented in this volume of RIMS Kôkyûroku Bessatsu are in final form and refereed.We give an expression of holomorphic tubular neighborhoods around elliptic curves embedded in blow-ups of the projective planes at general nine points in terms of special functions. The existence of holomorphic neighborhoods enables us to give a gluing construction of a family of K3 surfaces
Protected Culture for Vegetable and Small Fruit Crops: Types of Structures
No full textA protective structure is defined as any structure designed to modify the environment in which plants are grown. Protective structures, such as greenhouses, screen houses, and tunnels, are known worldwide as production systems for high-quality vegetable and fruit crops.
This minor revision by Shinsuke Agehara adds updated information regarding 2015 revisions to the Worker Protection Standards in the last paragraph, and removes one former author no longer affiliated with UF.
https://edis.ifas.ufl.edu/hs1224
Previous version: Santos, Bielinski, Gary Vallad, and Emmanuel Torres-Quezada. 2013. “Protected Culture for Vegetable and Small Fruit Crops: Types of Structures”. EDIS 2013 (7). https://journals.flvc.org/edis/article/view/121080
Pathogenesis of antiphospholipid antibodies : Impairment of fibrinolysis and monocyte activation via the p38 mitogen-activated protein kinase pathway
No full textAntiphospholipid syndrome (APS) is characterized by recurrent thrombosis or pregnancy morbidity associated with antiphospholipid antibodies (aPL). Impaired fibrinolysis is a contributing factor for the development of thrombosis, and the effect of aPL in the fibrinolytic system has been investigated. Impaired release of tPA and enhanced release of PAI-1 after endothel activation is reported in patients with APS. Elevated Lipoprotein (a) levels have been found in APS, which results in inhibition of fibrinolytic activity. Phospholipid-bound β2-glycoprotein I (β2GPI) is a major autoantigen for aPLs. β2GPI exerts both anti-coagulant and pro-coagulant properties mainly by interacting with other phospholipid-binding proteins such as coagulation factors and protein C. Dramatic increase in the affinity of β2GPI to the cell surface is induced by binding of pathogenic anti-β2GPI antibodies, which may modify the physiological function of β2GPI and may affect the coagulation/fibrinolysis balance on the cell surface. Using chromogenic assays for measuring fibrinolytic activity, we demonstrated that addition of monoclonal anticardiolipin antibody (aCL) decreases the activity of extrinsic/intrinsic fibrinolysis. Significantly lower activity of intrinsic fibrinolysis was also demonstrated in the euglobulin fractions from APS patients. Endothelial cells and monocytes are activated by aPLs in vitro, resulting in production of tissue factor (TF), a major initiator of the coagulation system. Recently, aPLs are reported to induce thrombocytes to produce thromboxane. The importance of apoE receptor 2 on platelets for the binding of artificially-dimerized β2GPI was suggested. By investigating aPL-inducible genes in peripheral blood mononuclear cells, we found that mitogen-activated protein kinase (MAPK) pathway was up-regulated. Using monocyte cell line, phosphorylation of p38 MAPK, NF-κB translocation to the nuclear fraction, and up-regulated TF mRNA expression were demonstrated after treatment with monoclonal aCL. These phenomena were observed only in the presence of β2GPI. Moreover, a specific p38 MAPK inihibitor SB203580 decreased aCL/β2GPI-induced TF mRNA expression. Thus, aCL/β2GPI plays dual roles in the pathogenesis of APS, firstly by deranging fibrinolytic system and secondly by activating monocytes, endothelial cells and thrombocytes to produce tissue factor or thromboxane
Correction to: Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan
No full textThe article Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan, written by Mitsuhiko Nose, Momoka Tada, Rika Kojima, Kumiko Nagata, Shinsuke Hisaka, Sayaka Masada, Masato Homma and Takashi Hakamatsuka, was originally published Online First without open access. After publication in volume 71, issue 4, page 711–722 the author decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</jats:p
Long-term trends in food habits of Asiatic black bears in the Misaka Mountains on the Pacific coast of central Japan
No full textPatch size determines the strength of edge effects on carabid beetle assemblages in urban remnant forests
No full textHabitat fragmentation due to urbanization is increasing rapidly worldwide. Although patch area and edge effect are both important determinants of species diversity and the number of individuals in fragmented landscapes, studies that tested interaction between two effects were limited. Here we examined the interaction between area and edge effects on species richness and the number of individuals of carabids in highly fragmented forests in Tokyo, central Japan. We surveyed carabids in each of 26 forest patches (1.1-121.6 ha) using pitfall traps set in both edge and interior zones. First, we correlated the edge-to-interior differences of both species richness and the number of individuals with patch area. Second, we examined the interaction between patch area and distance to the edge on species richness and the number of individuals using generalized linear models. We found a significant decrease in carabid species richness and the number of individuals in edge zones. The edge-to-interior differences in both species richness and the number of individuals were positively correlated with patch area. Model selection revealed the evident interaction effects between patch area and distance to the edge: higher number of individuals was predicted in only large interior zones. Our results indicated that carabid beetle assemblages were influenced by the interaction between area and edge effects. Thus, in urban areas where small forest remnants dominate, circularizing the shape of the forest patches to maximize the core areas may be the most feasible and realistic means to preserve biodiversity
Probing the multi-gluon correlations through single-spin asymmetries
No full textWe study the single-spin asymmetries for the D-meson production,Drell-Yan lepton-pair production and the direct-photon production in the pp collision induced by the twist-3 three-gluon correlation functions in the transversely polarized nucleon. We present a corresponding polarized cross section formula in the leading-order with respect to the QCD coupling and a model calculation for the
asymmetries, illustrating the sensitivity to the form of the correlation functions
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