252 research outputs found
Elementy japońskich wierzeń i obrzędów w mandze Mieruko-chan. Dziewczyna, która widzi więcej Tomoki Izumiego
The aim of the article is to reflect on religious themes in contemporary Japanese comics. The manga Mieruko-chan by Tomoki Izumi is analyzed. The themes include the Japanese tradition of horror, derived from folk beliefs, as well as Shintō and Buddhist rituals. The author draws attention to religion as an important element of creating cultural reality and its function that makes it more attractive.The aim of the article is to reflect on religious themes in contemporary Japanese comics. The manga Mieruko-chan by Tomoki Izumi is analyzed. The themes include the Japanese tradition of horror, derived from folk beliefs, as well as Shintō and Buddhist rituals. The author draws attention to religion as an important element of creating cultural reality and its function that makes it more attractive
Molecular mechanisms of metabolic regulation of glioma stem cells by mTORC1 activationm
金沢大学博士(理学)博士論文 要旨Abstract/本文Full 以下に掲載:Journal of Biological Chemistry Published online in 2016.08.12 2016. American Society of Biochemistry and Molecular Biology (ASBMB). 共著者:Ahmed M. Hegazy, Daisuke Yamada, Masahiko Kobayashi, Susumu Kohno, Masaya Ueno, Mohamed A.E. Ali, Kumiko Ohta, Yuko Tadokoro, Yasushi Ino, Tomoki Todo, Tomoyoshi Soga, Chiaki Takahashi, Atsushi Hiraodoctoral thesi
(Table 3) Oxygen isotopic concentrations for olivines in particles from the DF2641 layer (Dome Fuji ice core)
All values relative to SMOW
(Table 2) Bulk analytical data for Dome Fuji silicate-rich particles
Fe2+/Fe3+ ratios were calculated from stoichiometric constraints. All values in wt%
(Table 4) Noble gas concentrations and He, Ne, Ar, Kr, and Xe isotopic ratios for three particles from the DF2641 layer (Dome Fuji ice core)
Blanks and noble gas data on fusion crusts from chondritic meteorites are shown for comparison
(Appendix A) Volumetric concentration of particles in the Dome Fuji ice core (depths of 2641.50 to 2641.92 m)
(Appendix A) Volumetric concentration of particles in the Dome Fuji ice core (depths of 2641.50 to 2641.92 m
(Table 1) Representative analyses of olivine, mesostasis, and magnetite in DF2641 particles (Dome Fuji ice core)
Values given in wt%
Uncoupling protein 3 attenuates generation of reactive oxygen species by interacting with thioredoxin 2 in the mitochondrial intermembrane space
Katsuya Hirasaka1*, Edward M Mills2, Shohei Kohno1, Tomoki Abe1, Chika Ikeda1, Tasuku Maeda1, Shigetada Kondo1, Ayako Maita1, Yuushi Okumura1 and Takeshi Nikawa1
Author Affiliations
1 Department of Nutritional Physiology, Institute of Health Biosciences, University of Tokushima, Tokushima, 770-8503, Japan
2 Division of Pharmacology/Toxicology, University of Texas at Austin, Austin, TX 78712, USAPoster presentation
Uncoupling protein 3 (UCP3) is primarily expressed in the inner membrane of skeletal muscle mitochondria. It has been proposed that UCP3 reduces production of reactive oxygen species (ROS) and oxidative damage. However, the mechanisms by which UCP3 attenuates ROS production are not well understood. Here we report that UCP3 interacts with the non-processed form of thioredoxin 2 (Trx2), a redox protein that is localized in mitochondria, but not processed Trx2, which is involved in cellular responses to ROS. The hydrophilic sequences within the N-terminal tail of UCP3, which faces the intermembrane space, are necessary for binding to Trx2. In addition, Trx2 directly associated with UCP3 through a mitochondrial targeting signaling sequence, was processed in the intermembrane space, and thereby allowing redox reactions. A bimolecular fluorescence complementation analysis demonstrated that the interaction of these proteins occurs in the mitochondrial intermembrane space. Furthermore, increased UCP3 expression significantly attenuated ROS production in isolated mitochondrial without effects on membrane potential, however this effect is lost by Trx2 knock down. These results suggest that UCP3 binds to Trx2 in the mitochondrial intermembrane space and attenuates ROS production.Pharmaceutical Science
Spin-orbit coupling in a hexagonal ring of pendula
journal_title: New Journal of Physics article_type: paper article_title: Spin–orbit coupling in a hexagonal ring of pendula copyright_information: © 2017 IOP Publishing Ltd and Deutsche Physikalische Gesellschaft license_information: cc-by Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. date_received: 2016-09-30 date_accepted: 2017-04-07 date_epub: 2017-05-1
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