610 research outputs found
Integrating CT Myocardial Perfusion and CT-FFR in the Work-Up of Coronary Artery Disease
No full textAdriaan Coenen, Marisa Lubbers and Koen Nieman were supported by a grant from the Dutch
Heart Foundation (NHS 2014T061).
Francesca Pugliese: This work forms part of the translational research portfolio of the NIHR
Cardiovascular Biomedical Research Unit at Barts, which is supported and funded by the NIHR.
Alexia Rossi: recipient of a Training Grant by the European Society of Cardiology (2014)
Clinical Value of Coronary Computed Tomographic Angiography in Patients With Stable Angina
No full textAnatomic or functional testing in stable patients with suspected CAD: contemporary role of cardiac CT in the ISCHEMIA trial era
No full textOne of the foundations of the management of patients with suspected coronary artery disease (CAD) is to avoid unnecessary invasive coronary angiography (ICA) referrals. However, the diagnostic yield of ICA following abnormal conventional stress testing is low. The ability of ischemia testing to predict subsequent myocardial infarction and death is currently being challenged, and more than half of cardiac events among stable patients with suspected CAD occur in those with normal functional tests. The optimal management of patients with stable CAD remains controversial and ischemia-driven interventions, though improving anginal symptoms, have failed to reduce the risk of hard cardiovascular events. In this context, there is an ongoing debate whether the initial diagnostic test among patients with stable suspected CAD should be a functional test or coronary computed tomography angiography. Aside from considering the specific characteristics of individual patients and local availability and conditions, the choice of the initial test relates to whether the objective concerns its role as gatekeeper for ICA, prognosis, or treatment decision-making. Therefore, the aim of this review is to provide a contemporary overview of these issues and discuss the emerging role of CCTA as the upfront imaging tool for most patients with suspected CAD.Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Nieman, Koen. University of Stanford; Estados UnidosFil: Carrascosa, Patricia. Diagnostico Maipu, Buenos Aires; ArgentinaFil: Campisi, Roxana. Diagnostico Maipu, Buenos Aires; ArgentinaFil: Ambrose, John A.. University of California; Estados Unido
Coronary spiral CT
No full textThis dissertation describes the use and clinical potential of ECG gated multislice
spiral computed tomography in patients with coronary artery disease. First the
use of other non invasive cardiac imaging, i.e. the previously mentioned
electron beam CT and magnetic resonance imaging is reviewed (chapter 2.1).
Part 3 contains studies related to the characteristics of multislice spiral CT for
the imaging of the heart and coronary arteries, and the diagnostic potential of
ECG gated spiral CT coronary angiography to detect and visualize obstructive
coronary artery disease in symptomatic patients, using conventional coronary
angiography as the standard of reference. Part 4 is focussed on the feasibility
and characteristics of coronary wall imaging by CT, including the assessment of
non calcified atherosclerotic plaque material. The usefulness of
contrast enhanced multislice spiral CT in symptomatic patients who previously
underwent coronary artery bypass grafting and percutaneous coronary
intervention with stent implantation is discussed in part 5. Finally, the first results with the latest generation 16 slice computed tomography scanners and
patient preparation with ~ receptor blockers are described in part 6, including a
review and future outlook on the continuing development and clinical use of
non invasive coronary angiography with spiral computed tomography
SOLVENT EFFECTS ON TRIPLET LIFETIMES---BENZENE AT LOW TEMPERATURES
No full textPresent address of G. C. Nieman: Department of Chemistry, Muskingum College, New Concord, Ohio 13762.""Author Institution: Department of Chemistry, University of RochesterThe lifetime of the lowest benzene triplet state has been shown recently to be strongly dependent, upon temperature, even near . We report here on the solvent dependence of the phosphorescence lifetime of benzene and methylbenzenes in the low temperature limit. At the lifetime of varies from 12.5 to 26.5 seconds depending upon the solvent. The shortest lifetimes are found with solvents which have excited states closest in energy to those of benzene. There is some indication of the formation of a weak exciplex and subsequent radiationless decay. The longest lifetimes are found with perfluorocarbon solvents (e.g., )
- …
