9 research outputs found
Does the Etiology of Pulp Necrosis affect Regenerative Endodontic Treatment Outcomes? A Systematic Review and Meta-Analyses
No full textObjective: To evaluate if there is a connection between the causes of pulp necrosis (eg, caries, trauma, dental anomaly) and the success of regenerative endodontic treatment. Methods: Electronic databases (PubMed, Scopus, Web of Science, Cochrane Central Register of Controlled Trials, Embase) were searched for studies on regenerative endodontic treatment, which used both clinical and radiographic evaluation of root maturation after at least 6 months of follow-up. The search terms “necrotic pulp”, “regenerative endodontic treatment”, “revascularization”, and “revitalization” were combined using Boolean operators. The main journals on endodontics and dental traumatology were additionally hand-searched. Studies were included if they specified the causes of pulp necrosis. The primary question under review was, “Does the cause of pulp necrosis affect the outcome of regenerative endodontic treatment?” Other factors such as tooth type, intracanal medicament, irrigation protocol, use of a collagen matrix, and the type of scaffold were evaluated for possible relation with the outcome. The risk-of-bias assessment for randomized and nonrandomized studies was performed separately, using a modified Cochrane Collaboration's tool and risk of bias in non-randomized studies of interventions-I tool, respectively. Meta-analysis was performed, when possible, between studies comparing treatment outcomes of teeth whose pulp necrosis had different etiology. The search strategy yielded 1197 items. After screening, 18 studies reporting 445 regenerative endodontic treatment cases were included. Results: The overall success rate for 274 teeth with trauma etiology was 94.8%, for 95 teeth with dens evaginatus etiology was 93.1%, and for 24 teeth with caries etiology was 96%. No significant difference was found between the results of regenerative endodontic treatment among teeth with trauma, dens evaginatus, and caries etiology (P = .055). Meta-analysis of studies comparing teeth with caries vs dens evaginatus and those with trauma vs caries confirmed that there was no evidence for difference in outcomes. Conclusion: Further randomized studies specifically testing such hypothesis are needed to confirm the preliminary results of this review
Turkish version of the Preschool Children’s Nutrition Screening Tool (NutriSTEP®): a validity and reliability study
No full textAbstract: Objective: In this study, it was aimed to evaluate the Turkish validity and reliability of the Preschool Children’s Nutrition Screening Tool (NutriSTEP®), which is used to determine the nutritional status of children in the preschool period. Subject/Methods: The sample of the study consists of 333 parents with children aged 3–5 years old living in Turkey, who voluntarily agreed to participate in the study and answered the Turkish NutriSTEP® form online. The forward and backward translation method was applied for the language validity of the Turkish form. Expert opinion was sought for content validity. Factor analyzes were applied to determine the construct validity of the Turkish form. Original NutriSTEP® and Iran NutriSTEP® were evaluated to assess cut-points. To evaluate the reliability of the Turkish version, the test–retest method was used. Results: As a result of expert opinion, the Content Validity Index was found to be 0.97. According to exploratory factor analysis, unlike the original NutriSTEP®, five sub-dimensions were obtained and the 13th question with a factor load of less than 0.30 was removed. According to the confirmatory factor analysis, it was shown that the scale was suitable for Turkish society. There were positive, high and statistically significant correlations between the NutriSTEP® scale test–retest scores (p < 0.01). Conclusion: The Turkish NutriSTEP® questionnaire is both valid and reliable for the screening of nutrition risk in preschool children of the Turkish population. © 2022, The Author(s), under exclusive licence to Springer Nature Limited
A literature review on the linear elastic material properties assigned in finite element analyses in dental research
No full textIntroduction: Finite element analysis (FEA) is a numerical procedure utilised in the engineering analysis of structures and is one of the most common numerical methods utilised in many research activities in dentistry such as implantology, prosthodontics and restoration. FEA can be considered a useful tool in order to describe the deformation aspects of dental components that cannot be measured easily by in vivo models. The geometry, material properties, finite element model (mesh structure) and boundary conditions defined for a particular FEA setup are the factors affecting the accuracy of the results of a FEA. Most especially, material models employed in FEA play a critical role, however, the literature cannot provide standard material models and data in agreement to be defined in the FEA studies handled specifically for human teeth. The aim of this study is reviewing the most utilised data related to material properties (limited to linear homogeneous isotropic material model) of the tooth components, evaluate the sources and reasons for the different values defined in dental research and provide filtered material data which can be utilised in related FEA studies. Material and methods: Electronic databases (PubMed and Web of Science) were reviewed for publications on FEA utilised in dentistry research. 155 research publications in total were considered in this paper. The search keywords of “finite element analysis”, “finite element study”, “mechanical properties” and “teeth” were combined through Boolean operators. The primary question under review was: “How were the material properties of the tooth components and numerical ranges, which are assigned in a FEA utilised in dental research, obtained and verified?”. Results: It was possible to determine sixteen different elastic modulus (EM) and seven Poisson’ ratio (PR) values for enamel, eighteen EM and five PR values for dentin, sixteen EM and four PR values for periodontal ligament, eight EM and one PR values for pulp, ten EM and five PR values for cementum, twelve EM and four PR values for cortical bone, and eleven EM and four PR values for cancellous bone. As a result, it was seen that various EM, PR, density and strength values were considered and these were obtained from a limited number of FEA studies. Conclusion: Average ranges for the core material properties such as EM, PR, density and strength values to be utilised in a FEA set up were presented. Further studies, specifically on determination of the mechanical properties of tooth components are still needed in order to successfully utilise them and confirm the accuracy of the FEA studies related to dental research
Regional disparities in turkey: A socio-economic perspective
No full textEconomic development, for any country, is one of the most important objectives to be achieved. However, development cannot be realized in all regions and provinces of a county at the same time and speed. Turkey also struggles against a persistent economic development problem among regions in east-west and coast-inland for many years. This study aims to analyze the regional inequalities in Turkey under the scope of economic, demographic and social indicators from 2007 to the latest data. The results indicate that TR-10 Istanbul is the engine region of Turkey in terms of industrialization and development with the highest contribution (31%) based on service and industry sectors, to the gross value added. Other industrialized regions are the Aegean region where localization economies mainly dominated and the East Marmara and TR51-Ankara regions where urbanization economies operated in. Agricultural activities heavily concentrated in Aegean, Antalya, Konya and Şanlıurfa regions. In these regions, participation in the labour market is also very high. However, the highest income inequality and poverty is also found in TR10, TR62 and TR21 regions. The less developed region is the Southeast Anatolian region in terms of low income, education, health and high unemployment, young population and immigration rates. © 2020 The Author. Journal Compilation
Quest and journey in Orhan Pamuk's novels
No full textArayış ve yolculuk, ilk anlatılardan günümüze kadar edebiyattaki yerini koruyan, kişinin olgunlaşma, büyüme, oluşum, dönüşüm gibi süreçlerini anlatmak için başvurulan temel temaların başında gelmektedir. Arayış ve yolculuk temaları vesilesiyle kişinin iç dünyasındaki iniş ve çıkışların bu denli aktarılabilmesi, kuşkusuz romanlar için bu temaları vazgeçilmez yapan nedenlerdendir. Romanlarında, kişilerinin içsel derinliklerini ve gelişim süreçlerini her yönüyle okuyucuya sunmayı amaçlayan Orhan Pamuk’un romancılığı için ise arayış ve yolculuk, en elverişli temalardan biri olmuştur. Bu çalışmada, Orhan Pamuk’un romanlarında arayış ve yolculuk temasının nasıl yansıma bulduğu incelenmiştir. Yazarın romanlarında arayışın ve yolculuğun roman kişileri için hangi sebeplerle ortaya çıktığı, romanlarda hangi şekillerde görüldüğü ve roman kişileri için nasıl sonuçlar doğurduğu göz önüne serilmeye çalışılmıştır. Bu çalışmada aynı zamanda, arayışın ve yolculuğun birbiriyle ilişkili iki tema oluşunun, Orhan Pamuk’un romanlarında da aynı şekilde tezahür edip etmediği tespit edilmeye çalışılmıştır. Üç ana bölümden oluşan çalışmanın birinci bölümünde, arayış ve yolculuk kavramları açıklanmaya çalışılmış olup kavramların geçmişten günümüze olan uzantısı ele alınmıştır. Çalışmanın ikinci bölümünde, arayışın ve yolculuğun Orhan Pamuk’un edebi kişiliğindeki algısı incelenmiş ve bu anlayıştan hareketle ise üçüncü bölümde, arayış ve yolculuk temasının yazarın romanlarındaki karşılığı ortaya koyulmaya çalışılmıştır.Search and journey are among the main themes used to describe the processes such as the maturation, growth, formation and transformation of the hero, which has preserved its place in literature from the first narratives to the present day. The fact that the ups and downs of the hero's inner world can be conveyed so much on the occasion of the quest and journey themes is undoubtedly one of the reasons that make these themes indispensable for the novels. For Orhan Pamuk, who aims to present the inner depths and development processes of his heroes to the reader in all aspects in his novels, quest and journey have been one of the most favorable themes.
In this study, it has been examined how the theme of seeking and journey is reflected in Orhan Pamuk's novels. In the novels of the author, it has been tried to reveal the reasons for the search and the journey for the characters of the novel, in what ways it is seen in the novels and what results it has for the characters of the novel. In this study, it has also been tried to determine whether the two interrelated themes of search and journey are manifested in the same way in Orhan Pamuk's novels.
In the first part of the study, which consists of three main parts, the concepts of seeking and journey are tried to be explained and the extension of the concepts from the past to the present is discussed. In the second part of the study, the perception of search and journey in Orhan Pamuk's literary personality was examined, and based on this understanding, in the third part, the correspondence of the search and journey theme in the author's novels was tried to be revealed
The state of additive manufacturing in dental research – A systematic scoping review of 2012–2022
No full textBackground/purpose: Additive manufacturing (AM), also known as 3D printing, has the potential to transform the industry. While there have been advancements in using AM for dental restorations, there is still a need for further research to develop functional biomedical and dental materials. It’s crucial to understand the current status of AM technology and research trends to advance dental research in this field. The aim of this study is to reveal the current status of international scientific publications in the field of dental research related to AM technologies. Materials and methods: In this study, a systematic scoping review was conducted using appropriate keywords within the scope of international scientific publishing databases (PubMed and Web of Science). The review included related clinical and laboratory research, including both human and animal studies, case reports, review articles, and questionnaire studies. A total of 187 research studies were evaluated for quantitative synthesis in this review. Results: The findings highlighted a rising trend in research numbers over the years (From 2012 to 2022). The most publications were produced in 2020 and 2021, with annual percentage increases of 25.7% and 26.2%, respectively. The majority of AM-related publications in dentistry research originate from Korea. The pioneer dental sub-fields with the ost publications in its category are prosthodontics and implantology, respectively. Conclusion: The final review result clearly stated an expectation for the future that the research in dentistry would concentrate on AM technologies in order to increase the new product and process development in dental materials, tools, implants and new generation modelling strategy related to AM. The results of this work can be used as indicators of trends related to AM research in dentistry and/or as prospects for future publication expectations in this field
Exploring the integrated effects of transcranial random noise stimulation and visual perceptual learning: insights from the perceptual template model
No full textPostoperative Outcomes of One-Step Implant-Based Breast and Ovarian Surgery in High-Penetrance Gene Mutation: A Single-Center Experience
No full textBackground/Objectives: This study was designed to evaluate skin-sparing mastectomy with implant reconstruction complication rates in patients operated on due to high penetrant gene profile. All patients went to skin-sparing mastectomy with implant reconstruction and risk-reducing salpingo-oophorectomy. The effect of radiotherapy and chemotherapy on wound healing is a frequently discussed topic in the literature. However, studies on the effect of these on patients undergoing implant-based reconstruction are rare. In our clinic, two surgeries are performed under the same anesthesia and it is aimed to investigate the effect of this situation on complications in this rare patient group. In this retrospective study, we report our clinical experience regarding complication rates due to these factors among the high penetrant gene group. Methods: Between June 2022 and June 2024, 61 patients were grouped according to demographic data. Post-operative complications were defined as any of the following: major complications which were active bleeding or wound dehiscence; minor complications which were hematoma, seroma, surgical-site infection, <20% skin or nipple necrosis, and reoperation due to wound dehiscence or any other complication. Patients were compared in terms of complications according to whether they received previous radiotherapy (RT), neoadjuvant chemotherapy (CT), or underwent skin-reducing mammoplasty. Results: Patients receiving neoadjuvant chemotherapy, patients receiving preoperative RT, and patients undergoing skin-reducing mastectomy were compared in terms of major and minor complications. While neoadjuvant CT and preoperative RT only increased the risk of seroma, it was found that skin-reducing mastectomy had no significant effect on complication rates. Conclusions: Skin-sparing mastectomy with implant reconstruction and risk-reducing salphingo-oophorectomy is a comprehensive operation method in this patient group. Complication control can be achieved by performing two surgeries in a single anesthesia period, using the spy immunofluorescence device for vascularization control, and performing all surgeries with the same experienced team
The effect of implicit learning on functional connectivity in schizophrenia
No full textIntroduction Neuronal plasticity, or the ability to change and adapt in response to experiences, learning, or environment, is frequently disrupted in schizophrenia and contributes to disease-associated cognitive deficits and functional impairments.Methods In this study, we investigated the neuroplasticity alterations of schizophrenia patients in the cortico-striato-cerebellar circuits associated with implicit learning using a reward-enhanced Serial Reaction Time Task (SRTT) by resting-state functional MRI (rs-fMRI). Forty-two schizophrenia patients and 25 healthy controls underwent pre- and post-task rs-fMRI to evaluate changes in functional connectivity.Results Behavioral results indicated that all participants demonstrated shorter reaction times during sequential blocks, schizophrenia patients exhibited lower accuracy suggesting diminished implicit learning. Schizophrenia patients exhibited increased connectivity across cortico-striatocerebellar circuits, which became even more robust and widespread following task completion. Despite impaired performance, this post-task hyperconnectivity may reflect a compensatory mechanism attempting to recruit additional neural resources-albeit in a dysfunctional or inefficient manner. Data-driven analyses confirmed the post-task differences between groups, identifying task-induced connectivity changes in thalamo-cortico-cerebellar circuits as the strongest predictors of a group membership.Discussion These findings underscore the role of neuroplasticity impairments in schizophrenia-related cognitive deficits, highlighting potential neural markers for clinical differentiation and paving the way for targeted interventions.Bilimsel Arastimath;rma [TGA-2021-22567]The author(s) declare that financial support was received for the research and/or publication of this article. This research was funded by Bilimsel Ara & scedil;t & imath;rma Proje/No: TGA-2021-22567, which provided financial support for the submission and publication of this manuscript. The views expressed in this paper are those of the authors and do not necessarily reflect the official policy or position of Bilimsel Ara & scedil;t & imath;rma Proje
