1,721,185 research outputs found
Perioperative safety and complications in treatment of oral and maxillofacial surgery patients under general anesthesia with obstructive sleeping disorders
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Gas- und druckabhängige Auswirkung des Pneumoperitoneums auf die abdominelle Wundheilung am Kleintiermodell
No full textThe aim of this randomised study in the animal model was to explore possible gas- and pressure-dependend effects of pneumoperitoneum on abdominal wound healing. Carbon dioxid (CO2) and helium were analyzed using two different animal adapted pressure levels in comparison to controls (no pneumoperitoneum). Altogether, 78 Sprague-Dawley rats were randomized to 10 examination groups. Postoperative wound healing was assessed clinically. The animals were killed after 5 and 10 days, and the abdominal wall was explanted for subsequent histopathologic examinations of the laparotomy wound. The granuloma formation in hematoxylin and eosin-stained sections was analyzed. Infiltration of macrophages (CD68) and expression of matrix metalloproteinase 13 (MMP-13) were examined by immunohistochemistry. The collagen type 1 to type 3 ratio was investigated by cross-polarization microscopy after Sirius Red staining. Clinically, no differences were found with regard to postoperative wound healing between groups. After 5 and 10 days, the percentages of CD68-positive cells and granuloma formation did not differ between the groups. In contrast, after both 5 and 10 days, the expression of MMP-13 and the collagen 1 to 3 ratio were higher after helium pneumoperitoneum than in the control animals. These differences were statistically significant after 5 days. Different pressure levels had no impact on wound healing parameters. In conclusion, our comparative investigation of the insufflation gases CO2 and helium showed no marked influence of pneumoperitoneum on abdominal wound healing
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Der Verlauf der kutanen Mikrozirkulation am proximalen Oberschenkel nach pertrochantärer Femurfraktur unter dem Aspekt verschiedener operativer Zugangswege : eine Pilotstudie mit dem O2c-Messgerät
No full textPerioperative inflammatory response in major fracture: do geriatric patients behave differently?
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Evaluation des morphologischen Alterungsprozesses chirurgisch relevanter Gesichtspartien mittels optischer dreidimensionaler Oberflächenscans
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