133 research outputs found
Selective Synthesis of C4-Functionalized Benzofurans by Rhodium-Catalyzed Vinylene Transfer: Computational Study on the Cyclopentadienyl Ligand
No full textKitano J., Nishii Y., Miura M.. Selective Synthesis of C4-Functionalized Benzofurans by Rhodium-Catalyzed Vinylene Transfer: Computational Study on the Cyclopentadienyl Ligand. Organic Letters. 24(31), 5679-5683, (2022), 12 August 2022; ©2022 American Chemical Society. https://doi.org/10.1021/acs.orglett.2c02030.Benzofuran is a privileged structure in many bioactive compounds; however, the controlled synthesis of C2,C3-non-substituted benzofurans has been scares. In particular, cumbersome multistep processes are inevitable for the most inaccessible C4-substituted isomers. Herein, we report a Rh-catalyzed direct vinylene annulation of readily available m-salicylic acid derivatives with vinylene carbonate to achieve selective construction of C4-substituted benzofurans. The Weinreb amide directing group facilitated the following product derivatization. The reaction mechanism was investigated by DFT calculations
Selective Synthesis of C4-Functionalized Benzofurans by Rhodium-Catalyzed Vinylene Transfer: Computational Study on the Cyclopentadienyl Ligand
No full textKitano J., Nishii Y., Miura M.. Selective Synthesis of C4-Functionalized Benzofurans by Rhodium-Catalyzed Vinylene Transfer: Computational Study on the Cyclopentadienyl Ligand. Organic Letters. 24(31), 5679-5683, (2022), 12 August 2022; ©2022 American Chemical Society. https://doi.org/10.1021/acs.orglett.2c02030.Benzofuran is a privileged structure in many bioactive compounds; however, the controlled synthesis of C2,C3-non-substituted benzofurans has been scares. In particular, cumbersome multistep processes are inevitable for the most inaccessible C4-substituted isomers. Herein, we report a Rh-catalyzed direct vinylene annulation of readily available m-salicylic acid derivatives with vinylene carbonate to achieve selective construction of C4-substituted benzofurans. The Weinreb amide directing group facilitated the following product derivatization. The reaction mechanism was investigated by DFT calculations
sj-docx-1-cll-10.1177_09636897231194497 – Supplemental material for Mild Acute Graft-Versus-Host Disease Improves Outcomes After HLA-Haploidentical-Related Donor Transplantation Using Posttransplant Cyclophosphamide and Cord Blood Transplantation
No full textSupplemental material, sj-docx-1-cll-10.1177_09636897231194497 for Mild Acute Graft-Versus-Host Disease Improves Outcomes After HLA-Haploidentical-Related Donor Transplantation Using Posttransplant Cyclophosphamide and Cord Blood Transplantation by Fumiya Wada, Junya Kanda, Kimimori Kamijo, Masashi Nishikubo, Satoshi Yoshioka, Takayuki Ishikawa, Yasunori Ueda, Takashi Akasaka, Yasuyuki Arai, Kiyotaka Izumi, Hirokazu Hirata, Takashi Ikeda, Akihito Yonezawa, Naoyuki Anzai, Mitsumasa Watanabe, Kazunori Imada, Kazuhiro Yago, Naoki Tamura, Mitsuru Itoh, Yuki Masuo, Akane Kunitomi, Tomoharu Takeoka, Toshiyuki Kitano, Nobuyoshi Arima, Masakatsu Hishizawa, Kohsuke Asagoe, Tadakazu Kondo and Akifumi Takaori-Kondo in Cell Transplantation</p
A Stereo-Panoramic Telepresence System for Construction Machines
No full textWorking machines in construction sites or emergency scenarios can operate in situations that can be dangerous to an operator both
for direct control of the machine or teleoperation in co-presence. Remote operation has been typically hindered by limited sense
of presence of the operator in the remote of the environment to due the reduced field of view of cameras. Starting from these
considerations we are introducing a novel real-time panoramic telepresence system for construction machines. This system does
allow fully immersive operations in critical scenarios while keeping the operator in a safe location at moderate distance from the
construction site. An omnidirectional stereo vision head mounted over the machine acquires and streams data to the operator with a
streaming technique that focuses on the current direction of site of the operator. According to the motion of the operators head, the
telepresence system will determine the involved cameras to use and the appropriate region of interest in cameras. The operator uses
a head-mounted display to experience the remote site also with the possibility to view digital information overlaid to the remote
scene as a type of augmented reality. The paper addresses the design and architecture of the system starting from the vision system
and then proceeding to the immersive visualizatio
Chiral Algebras of (0, 2) Models
No full textSigma models with (0, 2) supersymmetry in two dimensions possess quasi-topological sectors characterized by chiral algebras. In this thesis, we study these chiral algebras and explore their nonperturbative aspects. The chiral algebras of (0, 2) models emerge when one considers the cohomology of local operators with respect to one of the supercharges, and provide infinite-dimensional generalizations of the chiral rings of (2, 2) models. Perturbatively, they enjoy rich math-ematical structures described by sheaves of chiral differential operators. Nonperturba-tively, however, they vanish completely for certain (0, 2) models with no left-moving fermions. Examples include the models in which the target spaces are the complete flag manifolds of compact semisimple Lie groups. The vanishing of the chiral algebra of a (0, 2) model implies that supersymmetry is spontaneously broken in the model, which in turn suggests that no harmonic spinors exist on the loop space of the target space. We analyze this supersymmetry breaking using holomorphic Morse theory on the loop space in the case where the target space is CP1. As expected, we find that instantons interpolate between pairs of perturbative supersymmetric states, thereby lifting them out of the supersymmetric spectrum
Habitar el suelo. Aproximaciones estéticas hacia un habitar en relación
No full textThis text analyzes different contemporary architectural and sculptural materializations distinguishable because of the relational and contingent approach to all that surrounds us. From a sensitive approach and articulation towards what coexists, the spatial configurations exhibited here are an example of a way of doing, of an ethic and a technique, which try to inhabit this world in relation. This is perceptible in the approach and listening to the surroundings of Junya Ishigami’s architecture or in the configuration next to the things of Josu Bilbao’s floor sculpture. They are aesthetic configurations that expose, rescuing Judith Butler’s words, the irremediably relational and contingent condition of our existence. And from the manifest interdependence towards what surrounds and conditions us, these configurations are an example of what Adriana Cavarero proposes as "inclined geometry". This author understands inclination as an approach that, appearing outside itself, tends to the outside, in manifest structural interdependence of the subject towards that which coexists. This text exposes that inclined geometry through the spatial configurations of Junya Ishigami, Ryue Nishizawa, Gordon Matta-Clark and Josu Bilbao, as a possibility of inhabiting an unstable world.; Este texto analiza diferentes materializaciones arquitectónicas y escultóricas contemporáneas que se distinguen por un acercamiento relacional y contingente hacia todo aquello que nos rodea. Desde un acercamiento y articulación sensible hacia lo que coexiste, las configuraciones espaciales expuestas aquí son muestra de una manera de hacer, de una ética y una técnica, que tratan de habitar este mundo en relación. Eso es perceptible en el acercamiento y escucha hacia el entorno de la arquitectura de Junya Ishigami o en la configuración junto a las cosas de la escultura de suelo de Josu Bilbao. Son configuraciones estéticas que exponen, rescatando las palabras de Judith Butler, el carácter irremediablemente relacional y contingente de nuestra existencia. Y desde la interdependencia manifiesta hacia aquello que nos rodea y condiciona, estas configuraciones son ejemplo de lo que Adriana Cavarero propone como "geometría inclinada". Esta autora entiende por inclinación un acercarse que, asomándose fuera de sí, tiende al exterior, en manifiesta interdependencia estructural del sujeto hacia aquello con lo que coexiste. En este texto se expone esa geometría inclinada a través de las configuraciones espaciales de Junya Ishigami, Ryue Nishizawa, Gordon Matta-Clark y Josu Bilbao, como posibilidad de habitar un mundo inestable
並行集団（パラレルな場）が持つ電気生理学的機序の解明
No full textOsaka Metropolitan University (大阪公立大学)博士（保健学）学位記番号：論保健学第2号, 主査：石井, 良平第1章出典
Junya Orui, Keigo Shiraiwa, Fumie Tazaki, Takao Inoue, Masaya Ueda, Keita Ueno, Yasuo Naito, Ryouhei Ishii; Social Buffering Effects during Craft Activities in Parallel Group Session Revealed by EEG Analysis and Parasympathetic Activity. Neuropsychobiology 6 October 2023; 82 (5): 287–299. https://doi.org/10.1159/000531005
© 2023 The Author(s). Published by S. Karger AG, Basel
CC BY-NC 4.0
第2章出典
Orui, J., Shiraiwa, K., Tazaki, F. et al. Psychophysiological and interpersonal effects of parallel group crafting: a multimodal study using EEG and ECG. Sci Rep 14, 17883 (2024). https://doi.org/10.1038/s41598-024-68980-w
© The Author(s) 2024
CC BY-NC-ND 4.0doctoral thesi
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Interactive Cognitive Modeling: Understanding and Supporting IndividualHuman Cognition
No full textCognitive modeling, approximation of human cognitive functions in a computational system, is a traditional methodologyin the field of cognitive science. Usually this methodology has been used as a tool for scientific understanding of humanmind, and evaluated by fitting to human data. In this presentation, the author proposes a framework of interactive cognitivemodeling as an application of the above methodology for understanding and supporting individual human cognition. Theframework consists of cognitive architecture, visualization of the model behavior, knowledge database of personal userand sensing devices to include the users reaction. This presentation shows two systems of interactive cognitive modelingin the field of web browsing and photo browsing
Selective Synthesis of C4-Functionalized Benzofurans by Rhodium-Catalyzed Vinylene Transfer: Computational Study on the Cyclopentadienyl Ligand
No full textBenzofuran is a privileged structure in many bioactive
compounds;
however, the controlled synthesis of C2,C3-nonsubstituted benzofurans
has been scarce. In particular, cumbersome multistep processes are
inevitable for the most inaccessible C4-substituted isomers. Herein,
we report a Rh-catalyzed direct vinylene annulation of readily available m-salicylic acid derivatives with vinylene carbonate to
achieve selective construction of C4-substituted benzofurans. The
Weinreb amide directing group facilitated the following product derivatization.
The reaction mechanism was investigated by DFT calculations
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