207 research outputs found
Fast Transformations with Walsh-Hadamard Functions
No full textTitle: Fast Transformations with Walsh-Hadamard Functions, Author: Frank Y.Y. Shum, Location: ThodeIn this thesis, various techniques to generate Walsh-Hadamard functions are discussed. Efficient algorithms to compute the discrete Walsh-Hadamard transform have been derived and implemented. The design of a simple, but very fast, digital circuit that can perform the transform or its inverse is presented. These algorithms have been applied to the processing of speech for the investigation of bit rate reduction. Intelligible speech has been reconstructed from 8 or 4 dominant Walsh-Hadamard coefficients out of a field of 64, with a constant update time of 8 milliseconds, on a CDC-1700 computer.ThesisMaster of Engineering (ME
On fully nonlinear CR invariant equations on the Heisenberg group
No full textAbstractIn this paper we provide a characterization of second order fully nonlinear CR invariant equations on the Heisenberg group, which is the analogue in the CR setting of the result proved in the Euclidean setting by A. Li and the first author in Li and Li (2003) [21]. We also prove a comparison principle for solutions of second order fully nonlinear CR invariant equations defined on bounded domains of the Heisenberg group and a comparison principle for solutions of a family of second order fully nonlinear equations on a punctured ball
Рандомизированное контролируемое исследование эффективности электрофизиологического мониторинга дексмедетомидина у пациентов с повреждением головного мозга различного генеза
No full textBackground.At the same time, the main effect of the use of this drug is the elimination of the autonomic nervous system dysfunction and sympatholysis. It seems important to search for a method of indications and selection of a dose of dexmedetomidine in intensive care.Aims to improve the clinical effectiveness of the electrophysiological navigation of the prolonged use of dexmedetomidine in patients with brain pathology of various origins.Methods.The study included 83 patients 2050 days after the traumatic brain injury, anoxic damage; consequences of acute disorders of cerebral. 37 patients comprised the 1st intervention group with a clinical course of dexmedetomidine (male 28; female 9; average age 49.62.3 years) and 46 patients comprised the 2nd control group without pharmacological correction with dexmedetomidine (male 23; female 23, average age 512.5 years). Criteria for the inclusion of prolonged infusion of the drug dexmedetomidine (Orion Pharma, Finland) are based on heart rate variability (HRV) indicators characteristic of sympathetic hyperactivity, the target task of titration of doses of dexmedetomidine served as the parameters for achieving normal HRV indicators, the appearance of parasympathetic hyperactivity served as the basis for reducing the dosage of the drug or stopping it of application. HRV parameters were recorded before dexmetomedine infusion-initially, on 13; 45; 910; 1520 days of drug administration.Results.The starting dose of dexmedetomidine with sympathetic hyperactivity in patients was 0.12 to 0.24 g.kg1.hr1(average dose 0.160.01; total 200 mg/day). According to digital data from HRV, the effective dose of dexmedetomidine ED50 was 0.260.03 g.kg1.hr1(total daily 353.835.1 g) and was achieved on day 910 using dexmedetomidine.Conclusions.The protective role of dexmedetomidine with correction of sympathetic hyperactivity based on electrophysiological navigation according to the HRV is reliable in the following indicators: The improvement of consciousness; a significant decrease in the incidence of distress lung syndrome; septic shock; mortality.Обоснование. Дексмедетомидин используетсяприпроцедурной седациииликвидации симптомов симпатической гиперактивности (ажиотация, тахикардия, гипертензияит.п.). Основной эффект применения данного препарата устранение дисфункции автономной нервной системыисимпатолизис. Представляются важными поиск метода объективизации показанийиподбор дозы дексмедетомидинавинтенсивной терапии.Цель исследования улучшить возможности мониторингаиклиническую эффективность примененияидозирования дексмедетомидинаспомощью электрофизиологической навигацииупациентовспатологией головного мозга различного генеза.Методы.Висследование включено 83 пациента (51 мужчина, 32 женщины; средний возраст 50,381,7 года)впериод более 20днейспоследствиями: черепно-мозговой травмы (ЧМТ) (n=24; 28,9%); острого нарушения мозгового кровообращения (ОНМК) (n=17; 20,5%); аноксического повреждения головного мозга (n=16; 19,3%); субарахноидального кровоизлияния (n=23; 27,7%); нейрохирургических операцийнаголовном мозге (n=3; 3,6%). 37 пациентов (28 мужчин, 9 женщин; средний возраст 49,62,3 года) составили первую группу вмешательстваcкурсом клинического применения дексмедетомидинаи46 пациентов (23 мужчины, 23 женщины; средний возраст 512,5 года) вторую (контрольную) группубезфармакологической коррекции дексмедетомидином. Критерии начала пролонгированной инфузии препарата дексмедетомидина (фирмаOrionPharma, Финляндия) основанынапоказателях вариабельности ритма сердца (ВРС), характерныхдлясимпатической гиперреактивности; таргетированной задачей титрования дозы дексмедетомидина служили параметры достижения нормы показателей ВРС; появление парасимпатической гиперактивности служило основанием уменьшения дозировки препаратаилипрекращения его применения (использовались 5-минутные записи кардиоинтервалов (прибор Полиспектр-8 ЕХ фирмы Нейрософт, Россия)). Регистрировали следующие показатели ВРС: SI стресс-индекс Баевского (индекс напряжения регуляторных систем индекс напряжения)внормализованных единицах (н.е.); SDNN среднеквадратичное отклонение RR-кардиоинтерваловвмс; rMSSD среднеквадратичное отклонение разности двух смежных отсчетов RR-кардиоинтерваловвмс; pNN50% доля RR-кардиоинтерваловвпроцентах, отличающихсяотпредыдущего более чемна50 мс;TP общая мощность спектра частотвмсек2. Параметры ВРС регистрировалидоинфузии дексметомидина исходно,на13-и, 45-е, 910-е, 1520-е сут применения лекарственного препарата.Результаты.Стартовая доза дексмедетомидинапри симпатической гиперактивности составилаупациентовот0,12до0,24 мкг/кг/ч (средняя доза 0,160,01; суммарно 200 мкг/сут).Поцифровым данным ВРС эффективная доза дексмедетомидина ЭД50составила 0,260,03 мкг/кг/ч (суммарнозасутки 353,835,1 мкг)ибыла достигнутана910- й день применения дексмедетомидина.Заключение.Коррекция симпатической гиперактивностиприприменении дексмедетомидина вызывает повышение уровня сознания, снижает частоту возникновения септического шока, дистресс синдрома легких, летальность
A randomized controlled study of the effectiveness of electrophysiological monitoring of dexmedetomidine in patients with brain damage of various origins [Рандомизированное контролируемое исследование эффективности электрофизиологического мониторинга дексмедетомидина у пациентов с повреждением головного мозга различного генеза]
No full textBackground. At the same time, the main effect of the use of this drug is the elimination of the autonomic nervous system dysfunction and sympatholysis. It seems important to search for a method of indications and selection of a dose of dexmedetomidine in intensive care. Aims - to improve the clinical effectiveness of the electrophysiological navigation of the prolonged use of dexmedetomidine in patients with brain pathology of various origins. Methods. The study included 83 patients 20-50 days after the traumatic brain injury, anoxic damage; consequences of acute disorders of cerebral. 37 patients comprised the 1st intervention group with a clinical course of dexmedetomidine (male - 28; female - 9; average age 49.6 ± 2.3 years) and 46 patients comprised the 2nd control group without pharmacological correction with dexmedetomidine (male - 23; female - 23, average age 51 ± 2.5 years). Criteria for the inclusion of prolonged infusion of the drug dexmedetomidine (Orion Pharma, Finland) are based on heart rate variability (HRV) indicators characteristic of sympathetic hyperactivity, the target task of titration of doses of dexmedetomidine served as the parameters for achieving normal HRV indicators, the appearance of parasympathetic hyperactivity served as the basis for reducing the dosage of the drug or stopping it of application. HRV parameters were recorded before dexmetomedine infusion-initially, on 1-3; 4-5; 9-10; 15-20 days of drug administration. Results. The starting dose of dexmedetomidine with sympathetic hyperactivity in patients was 0.12 to 0.24 μg.kg-1.hr-1 (average dose 0.16 ± 0.01; total 200 mg/day). According to digital data from HRV, the effective dose of dexmedetomidine ED50 was 0.26 ± 0.03 μg.kg-1.hr-1 (total daily 353.8 ± 35.1 μg) and was achieved on day 9-10 using dexmedetomidine. Conclusions. The protective role of dexmedetomidine with correction of sympathetic hyperactivity based on electrophysiological navigation according to the HRV is reliable in the following indicators: The improvement of consciousness; a significant decrease in the incidence of distress lung syndrome; septic shock; mortality. © 2020 Izdatel'stvo Meditsina. All rights reserved
Chiral tetranuclear and dinuclear copper(II) complexes for TEMPO-mediated aerobic oxidation of alcohols : are four metal centres better than two?
No full textThe one-pot reaction of 3,5-di-tert-butyl-2-hydroxybenzaldehyde, (R)-2-aminoglycinol and Cu(OAc)2·2H2O in a 1 : 1 : 1 ratio in the presence of triethylamine led to the isolation of X-ray quality crystals of the chiral complex (R)-1 in high yield. The single crystal structure of (R)-1 reveals a tetranuclear copper(II) complex that contains a {Cu4(μ-O)2(μ3-O)2N4O4} core. A reaction using (1S,2R)-2-amino-1,2-diphenylethanol as precursor under the same conditions generated the chiral complex (S,R)-2; its structure was determined by single crystal X-ray crystallography and was found to contain a {Cu2(μ-O)2N2O2} core. Both (R)-1 and (S,R)-2 have been used for catalytic aerobic oxidation of benzylic alcohols in combination with the TEMPO (2,2,6,6-tetramethylpiperidinyl-1-oxyl) radical. (R)-1 selectively catalyses the conversion of various aromatic primary alcohols to the corresponding aldehydes with high yields (99%) and TONs (770) in the air, while (S,R)-2 exhibits less promising catalytic performance under the same reaction conditions. The role of the cluster structures in (R)-1 and (S,R)-2 in controlling the reactivity towards aerobic oxidation reactions is discussed
Politically-mediated affects: envy in Spinoza's Tractatus Politicus
No full textIn the Tractatus Politicus Spinoza argues that politically unequal societies can be extremely stable. This feature of his work is at odds with a view, common in the literature, that Spinoza is a democratically-minded author who defends inclusive political systems, and in this paper I consider how he thinks inequality can be sustained. I focus on his discussion of the ways in which envy can be offset or redirected; and I apply my conclusions to his notorious claim that women are not fit to rule
Natural Gas Production and CO2 Sequestration in a Class 2 Hydrate Accumulation: A Numerical Simulation Study
No full textLarge amounts of natural gas hydrates have been found in sub-oceanic deposits and beneath permafrost regions. It has the potential to become a major hydrocarbon resource in the near future. Research is needed to evaluate the production possibilities of this new resource. CH4 hydrate dissociation and production is an endothermic process and a production challenge is the reservoir temperature reduction. CO2 is thermodynamically favoured over CH4 in the hydrate form and it has been suggested to use CO2 to prevent cooling by replacement of CH4 hydrates with CO2 hydrates. This technique has three advantages: sequestration of CO2, increased CH4 production and maintaining formation stability. The effect of CO2 injection on the CH4 production from a hydrate reservoir has been investigated by numerical simulations. A sensitivity analysis on the CH4 production has been performed by varying the injection pressure, temperature, reservoir properties, hydrate blockage models, intrinsic kinetic rates for CO2 hydrate formation and numerical parameters. The research has been performed by running numerical simulations using the kinetic simulator STARS from CMG. A 3D homogeneous class 2 hydrate reservoir was constructed with a production well completed in the hydrate zone and an injection well completed in the free water zone, injecting liquid CO2 in the free water zone below the CH4 hydrate zone. The injection and production well pressure were regulated to create CO2 hydrate forming and CH4 hydrate dissociation conditions in the reservoir. The simulation results have shown that when CO2 is injected, the cumulative CH4 production can increase with 50-60 %, while storing significant amounts of CO2 simultaneously. 2 % of the injected CO2 was produced at the production well. CO2 hydrates were formed directly under the CH4 hydrates, supplying the dissociating CH4 hydrates with a low grade heat source. No upward moving front of CO2 was observed. It is concluded that CO2 injection only increases CH4 production when the temperature of the reservoir is too low to support further hydrate dissociation. The highest recovery rates are achieved with low injection pressures. Injection of CO2 in the gas phase is favoured and the intrinsic kinetic formation rate for CO2 hydrates is a major influence on the CH4 production. It is concluded that CO2 injection in a Class 2 hydrate reservoir could increase the CH4 production under certain conditions.Petroleum EngineeringGeotechnologyCivil Engineering and Geoscience
Living with Disability: A Historical Perspective on Socialist-era Housing in Romania 1959-1989
No full textNicolae Ceausescu's regime in Romania, beginning in 1965, aimed at industrializing the country by increasing the labor force, leading to the development of large-scale housing blocks across Romania following the Soviet model. Urban planning and design were instrumental in serving political objectives such as industrial development, urban homogenization, and social control. However, amidst these grand architectural visions, the experiences of individuals with disabilities have been largely overlooked. The government's policies toward individuals with disabilities reflected a belief that they were incapable of contributing to a socialist society, resulting in their marginalization and neglect. This thesis explores the experiences of individuals with motor disabilities in Romania during the 20th century, shedding light on their marginalized narratives within the context of socialist-era architectural decisions. Through historical analysis, case studies of housing developments and interviews with residents, the research will be led by the question “How did the political policies and architectural design strategies employed during the construction of socialist era building blocks in Romania shape the living conditions, accessibility, and well-being of the disabled community?" The paper argues that architecture acted as a barrier to the integration of the disabled community, directly leading to increased institutionalization rates among individuals with physical and motor disabilities, as it substantially hindered their ability to lead typical lives within their homes. The thesis contributes to contemporary discussions on inclusive urban planning and societal perceptions, highlighting the importance of considering diverse perspectives and understanding the history of the context in architectural design and policymaking.AR2A011Architectural History ThesisArchitecture, Urbanism and Building Science
News Representation in Newspaper ,,Segodnya" for 1919 and 1925
No full textDarbs veltīts 1919. un 1925. gadu avīzē „Segodnja” zinu materiāla reprezentācijai. Autors salīdzina avīzes „Segodnja” izdevēju izmantoto stratēgiju reprezentējot notikumus sagatavojot kārtējo noteikta laika perioda numurus. Pirmajā izpētes dalā autors nosaka izmantotas jēdzienus, tādus kā „zinu materiāls”, „notikums”, „normas”. Otra dala veltīta noteiktā perioda zinu materiāla analīzei.The paper is devoted to the research of the representation of news in newspaper “Segodnya” n 1919 and 1925 y.y. The author makes a comparison of strategies which editors of “Segodnya” used to consider while newspaper was issued. The first chapter of paper examines concepts which author involves in his research, such as “news”, “event”, “normalcy”. The second part of research is devoted to analysis of news in 1919 and 1925 y.y.
The research can be interesting to philologists, dealing with evolution of Russian press in Latvia during the first half of XX century, as well as to all inquisitive readers
Hoogbouw, gebouwvorm en windbelasting
No full textMet als bijlage: A0 poster. In dit afstuderen wordt een onderzoek gedaan naar de invloeden van openingen dwars door een gebouw op de windbelasting. De informatie die uit de resultaten voortkomen dienen als hulpmiddel voor de bouwkundige ontwerpers. Wanneer bouwkundige ontwerpers informatie beschikken over de invloeden van gebouwvormen op de wind, kan hier in een vroeg stadium rekening mee gehouden worden. Dit zal resulteren in tijd en geldbesparing. Allereerst is er een vergelijking gedaan tussen verschillende methoden voor het bepalen van de windbelasting. Vervolgens is er gekeken naar de gevolgen van de verschillende windbelastingen op de hoofddraagconstructie.Architectur
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