3,318 research outputs found
Kim Hwa Soon
No full text학위논문(석사)--아주대학교 일반대학원 :간호학과,2009. 2Ⅰ. 서론
A. 연구의 필요성 ----1
B. 연구목적 ---- ----3
C. 용어정의-------4
Ⅱ. 문헌고찰 ------5
Ⅲ. 연구방법
A. 연구설계 ----10
B. 연구대상 ----10
C. 연구도구 -----------10
D. 자료수집 방법 및 절차 -----------11
E. 윤리적 고려사항 ----------12
F. 자료분석 방법 -----------12
G. 연구의 제한점 -----------13
Ⅳ. 연구결과
A. 연구 대상자의 일반적 특성 --------14
B. 연구 대상자의 요로감염 관리에 대한 지식정도 ---15
C. 연구 대상자의 요로감염 관리에 대한 실천정도---18
D. 요로감염 관리의 지식과 실천정도와의 관계 -----21
E. 일반적 특성에 따른 요로감염 관리에 대한 지식과
실천정도------22
Ⅴ. 논의 ----------24
Ⅵ. 결론 및 제언 -------32
참고문헌------34
부 록 -----39
ABSTRACT------45Maste
A 2.4 GHz Linear SiGe Bipolar Power Amplifier for IEEE 802.11b/g Wireless LAN Applications
No full textAssociation of the Interleukin-1 beta and Interleukin-1 Receptor Accessory Protein Gene Polymorphisms with Persistent Hepatitis B Virus Infection and Hepatocellular Carcinoma
No full text학위논문(석사)--아주대학교 일반대학원 :의학과,2010. 2ABSTRACT ⅰ
TABLE OF CONTENS ⅱ
LIST OF FIGURES ⅲ
LIST OF TABLES ⅳ
Ⅰ. INTRODUCTION 1
Ⅱ. MATERIALS AND METHODS 3
A. MATERIALS 3
1. Patients 3
2. DNA preparation 5
B. METHODS 5
1. Selection of the candidate genes (IL-1B and IL-1RAcP) and relevant single nucleotide polymorphisms 5
2. Genotyping of IL-1B and IL-1RAcP SNPs in the Korean patients 8
3. Statistical analyses 9
Ⅲ. RESULTS 10
Ⅳ. DISCUSSION 17
Ⅴ. CONCLUSION 21
REFERENCES 22
국문요약 27MasterBackground & Aims: The reasons for persistent hepatitis B virus infection (HBV) are unknown, but they are probably related to host immune factors. Interleukin-1β (IL-1β) plays significant roles in inflammation and immune defense via IL-1 receptor accessory protein (IL-1RAcP). We investigated whether genetic polymorphisms of IL-1B and IL-1RAcP genes are associated with persistent HBV infection and the presence of hepatocellular carcinoma (HCC).
Methods: We enrolled a total of 292 patients with chronic HBV infection (111 with chronic hepatitis, 95 with liver cirrhosis and 86 with HCC) and 107 healthy individuals who recovered from HBV infection. We assessed 28 SNPs in IL-1B and IL-1RAcP genes by using Illumina’s Sentrix array matrix chip.
Results: Four SNPs of IL-1B (-2023G>C, -581T>C, 289T>C, 3340A>G) and six SNPs of the IL-1RAcP (-51668T>A, -8261T>C, -8183A>G, -256C>T, 59264G>A, 65445A>G) showed biallelic polymorphism. IL-1B -2023 C allele, IL-1RAcP -8261 T allele and -8183 A allele were significantly associated with persistent HBV infection (OR, 1.63, P = 0.03, OR, 0.64, P <0.01 and OR, 0.20, P = 0.01, respectively). IL-1B 289 C allele was marginally associated with an increased risk for the presence of HCC (OR, 1.55, P = 0.04). On the haplotype analysis, IL-1B -2023C/-581C/2893C haplotype and IL-1RAcP -8261T/-8183A haplotype were associated with persistent HBV infection. There is no significant association between the haplotypes of IL-1B/IL-1RAcP and the presence of HCC.
Conclusions: The genetic polymorphisms of IL-1B -2023 C allele, IL-1RAcP -8261 T allele and -8183 A allele are probable host factors for persistent HBV infection
Derivation of mechanistic critical heat flux model for water based on flow instabilities
No full textThe critical heat flux (CHF) is a major parameter which determines the cooling performance and therefore the prediction of CHF with accuracy is of importance for the design and safety analysis of nuclear power plant (NPP). In this study, the mechanistic CHF model and correlation for water are derived based on flow excursion (or Ledinegg instability) criterion and the simplified two-phase homogeneous model. The relationship between CHF for the water and the principal parameters such as mass flux, heat of vaporization, heated length-to-diameter ratio, vapor-liquid density ratio and inlet subcooling is derived on the developed correlation. The developed CHF correlation predicts very well at the applicable ranges, 1 < P < 40 bar, 1,300 < G 27,00 kg/m(2)s and inlet quality is less than -0.1. The overall mean ratio of predicted to experimental CHF value is 0.988 with standard deviation of 0.046. Copyright (C) 1996 Elsevier Science Lt
Optimization of Carbon- and Binder-Free Au Nanoparticle-Coated Ni Nanowire Electrodes for Lithium-Oxygen Batteries
No full textA Au nanoparticle-coated Ni nanowire substrate without binder or carbon is used as the electrode (denoted as the Au/Ni electrode) for Li-oxygen (Li-O-2) batteries. A minimal amount of Au nanoparticles with sizes of <30 nm on a Ni nanowire substrate are coated using a simple electrodeposition method to the extent that maximum capacity can be utilized. This optimized, one body, Au/Ni electrode shows high capacities of 921 mAh g(Au)(-1), 591 mAh g(Au)(-1), and 359 mAh g(Au)(-1), which are obtained at currents of 300 mAg(Au)(-1), 500 mAg(Au)(-1), and 1000 mAg(Au)(-1) respectively. More importantly, the Au/Ni electrode exhibits excellent cycle stability over 200 cycles.close4
Activated natural porous silicate for a highly promising SiOx nanostructure finely impregnated with carbon nanofibers as a high performance anode material for lithium-ion batteries
No full textA highly promising anode material with an amorphous SiOx nanostructure finely impregnated with carbon nanofibers is presented. The nanostructure material has a unique integral feature in that carbon nanofibers smaller than several nm in diameter are finely dispersed in amorphous SiO x media in an aligned manner. The synthetic route to fabricate the nanostructure is very simple and easy, using natural porous silicate, sepiolite, activated through the process of sintering and acid treatments on carbon source-loaded sepiolite nanocomposites. Upon the treatments, the nanocomposite material is changed in respect of its structure and chemical composition from crystalline Mg silicate to the carbon nanofiber-impregnated amorphous SiO x phase (CNF-SiOx nanostructure), and the electrochemical activity is greatly improved. The CNF-SiOx nanostructure exhibits excellent electrochemical performance with a reasonably high capacity of approximately 720 mA h g-1 for a current density of 70 mA g -1 (C/10 rate) and outstanding rate capability with a capacity retention of 96.8% for a current density of 700 mA g-1 and 87% at 1400 mA g-1 relative to that at 35 mA g-1, even at a high electrode loading level above 8 mg cm-2. The cycling performance is also very stable, with a capacity retention of 94.7% over 50 cycles at a rate of 350 mA g-1 and with a Coulombic efficiency above 99%.close1
Reliability Assessment of Advanced Materials and Structures
No full textThis paper discusses the reliability assessment of advanced structures such as micro/nano structures, electronics packaging for modern electronic devices, high temperature structures such as nuclear power plants, rocket engines for space application. Characterization of advanced materials includes free-standing electrodeposited nano-crystalline nickel thin film, polysilicon, and piezoelectric thin film for MEMS/nano structures. Lead-free solders under pseudo-power cyclic thermal loading, impact loading and mechanical bending loading were
evaluated for reliability assessment of the advanced electronic packaging. Reliability assessment of Cu/SnAg double bump structures was performed for the 150μm pitch flip chip electronic packaging application. The 316L austenitic stainless steel for high-temperature components application such as in the primary side of liquid metal cooled fast breeder reactor (LMFBR) was tested under various temperatures where dynamic strain ageing occurs. The effects of dynamic strain ageing on the tensile behavior and fatigue behavior of 316L stainless steel have been identified.This work has been supported by the core research program of National Research
Foundation of Korea, and BK21 program of the Ministry of Education, Science and
Technology of Korea. Contributions by Dr. D. C. Baek, Mr. M. Kim for thin film research,
Dr. I. Kim, Dr. T. S. Park, Dr. S. Y. Yang, Dr. S. J. Ham, and Miss J. Y. Yoon for electronics
packaging research, and Dr. S. G. Hong, Dr. K. O. Lee, Dr. S. S. Yoon for research on high
temperature structures are greatly appreciated
Factors governing seawater carbonate dynamics in a macroalgal habitat
No full textPhotosynthetic organisms shift the dynamics of surface pCO2 driven by the sea surface temperature change (thermodynamic driver) by assimilating inorganic C from seawater. Here we measured net C uptake in a macroalgal habitat of coastal Korea for two years (2019-2020) and found that the macroalgal habitat contributed 5.8 g C m−2 month−1 of the net C uptake during the growing period (the cooling period, September−May). This massive C uptake changed the thermodynamics-driven seasonal dynamics such that the air−sea equilibrium of pCO2 was pushed into disequilibrium. The surface pCO2 dynamics during the cooling period was mostly influenced by the seasonal decrease in temperature and the proliferation of macroalgae, while the dynamics during the warming period (the stagnant period, June−August) closely followed that predicted based solely on the change in sea surface temperature (thermodynamic driver). In contrast to the phytoplankton-dominated off-shore waters (where phytoplankton populations are large in spring and summer), the impact of coastal macroalgae on surface pCO2 dynamics was most pronounced during the cooling period, when the magnitude of pCO2 change was as much as twice that resulting from temperature change. Our study shows that the distinctive features of the macroalgal habitat—in particular the seasonal temperature extremes (~18°C difference), the active macroalgal metabolism, and anthropogenic nutrient inputs—collectively influenced the seasonal decoupling of seawater and air pCO2 dynamics. Copyright © 2022 Kim, Lee, Han, Kim, Kim, Kim, Kim, Jeon and Shin.11Ysciescopu
Medium optimization for enhanced production of Rifamycin B by Amycolatopsis mediterranei S699: Combining a full factorial design and a statistical approach
No full textThis paper describes improved optimization method that combines the Plackett-Burman design, a full factorial design and the response surface method, which were used to optimize the medium for the production of rifamycin B by Amycolatopsis mediterranei S699. The five nutrients used to amend the medium were preliminary selected from 15 medium components based on the results of the Plackett-Burman design experiments and subsequent screening process using the full factorial design experiments was performed. Glucose, (NH(4))(2)SO(4), and corn steep liquor were found to be the best nutrients for the optimization of rifamycin B productions, and central composite design experiments indicated that the optimal concentrations of these nutrients were 63 g/L, 7.9 g/L, and 10 g/L, respectively. A bioreactor culture was used to investigate the production characteristics obtained when Amycolatopsis mediterranei S699 was grown in the determined optimum medium. Although cell growth stopped at 88 h, rifamycin B production continued, reaching its maximum value at the end of the experiment (172 h) after the glucose in the medium was completely consumed. The maximum cell concentration and rifamycin B titer were 8.6 g/L and 1260 mg/L, respectively. The combined optimization method described here is new and effective method for screening carbon and nitrogen sources as well as determining their optimum levels. (C) 2008 Elsevier Ltd. All rights reserved
A 2.4GHz SiGe Bipolar Power Amplifier with Integrated Diode Linearizer for WLAN IEEE 802.11b/g Applications
No full text- …
