11,199 research outputs found

    ‘It makes life so much easier’—experiences of users of the MicroGuide™ smartphone app for improving antibiotic prescribing behaviour in UK hospitals: an interview study

    No full text
    Objectives: To understand the impact on prescribing behaviour of an antimicrobial therapy guidelines smartphone app, in widespread use in hospitals in the UK.Methods: Twenty-eight doctors and five nurse prescribers from four purposively selected hospitals in the UK participated in behavioural theory-informed semi-structured interviews about their experiences of using the MicroGuide™ smartphone app. Data were analysed using a thematic content analysis.Results: Five themes emerged from the interview data: convenience and accessibility; validation of prescribing decisions; trust in app content; promotion of antimicrobial stewardship; and limitations and concerns. Participants appreciated the perceived convenience, accessibility and timesaving attributes of the app, potentially contributing to more prompt treatment of patients with time-critical illness. The interviewees also reported finding it reassuring to use the app to support decision-making and to validate existing knowledge. They trusted the app content authored by local experts and considered it to be evidence-based and up-to-date. This was believed to result in fewer telephone calls to the microbiology department for advice. Participants recognized the value of the app for supporting the goals of antimicrobial stewardship by promoting the responsible and proportionate use of antimicrobials. Finally, a number of limitations of the app were reported, including the risk of de-skilling trainees, cultural problems with using smartphones in clinical environments and software technical problems.Conclusions: The MicroGuide app was valued as a means of addressing an unmet need for updated, concise, trustworthy specialist information in an accessible format at the bedside to support safe and effective antimicrobial prescribing.</p

    Measuring Appropriate Antibiotic Prescribing in Acute Hospitals: Development of a National Audit Tool Through a Delphi Consensus

    No full text
    This study developed a patient-level audit tool to assess the appropriateness of antibiotic prescribing in acute National Health Service (NHS) hospitals in the UK. A modified Delphi process was used to evaluate variables identified from published literature that could be used to support an assessment of appropriateness of antibiotic use. At a national workshop, 22 infection experts reached a consensus to define appropriate prescribing and agree upon an initial draft audit tool. Following this, a national multidisciplinary panel of 19 infection experts, of whom only one was part of the workshop, was convened to evaluate and validate variables using questionnaires to confirm the relevance of each variable in assessing appropriate prescribing. The initial evidence synthesis of published literature identified 25 variables that could be used to support an assessment of appropriateness of antibiotic use. All the panel members reviewed the variables for the first round of the Delphi; the panel accepted 23 out of 25 variables. Following review by the project team, one of the two rejected variables was rephrased, and the second neutral variable was re-scored. The panel accepted both these variables in round two with a 68% response rate. Accepted variables were used to develop an audit tool to determine the extent of appropriateness of antibiotic prescribing at the individual patient level in acute NHS hospitals through infection expert consensus based on the results of a Delphi process

    A bio-inspired design of a hand robotic exoskeleton for rehabilitation

    No full text
    This paper presents the methodology for the design of a five-degree of freedom wearable robotic exoskeleton for hand rehabilitation. The design is inspired by the biological structure and mechanism of the human hand. One of the distinct features of the device is the cable-driven actuation, which provides the flexion and extension motion. A prototype of the orthotic device has been developed to prove the model of the system and has been tested in a 3D printed mechanical hand. The result showed that the proposed device was consistent with the requirements of bionics and was able to demonstrate the flexion and extension of the system. © 2018 Author(s). Published by AIP Publishing

    Going Beyond Counting First Authors in Author Co-citation Analysis

    No full text
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Re: Is giant cell reparative granuloma of the hand undertreated?

    No full text
    [No abstract available]BERTHEUSSEN KJ, 1983, J HAND SURG-AM, V8, P46; ENNEKING WF, 1986, CLIN ORTHOP RELAT R, P9; Giza E, 1997, J HAND SURG-AM, V22, P732, DOI 10.1016-S0363-5023(97)80137-2; LORENZO JC, 1980, AM J SURG PATHOL, V4, P551, DOI 10.1097-00000478-198012000-00006; Macdonald DF, 2003, CAN J SURG, V46, P471; Ugwonali O, 1999, J HAND SURG-AM, V24A, P1331; WOLD LE, 1986, AM J SURG PATHOL, V10, P491, DOI 10.1097-00000478-198607000-000060

    Left hand, right hand: Understanding laterality and its impact on surgery

    No full text
    Laterality, defined as the preferential use of one side of the body over the other, is a fundamental characteristic observed across species, and is deeply rooted in neurodevelopmental, genetic, and environmental factors. This review explores the concept of laterality, examining its role, modulation and expression in humans with a particular focus on its implications in plastic-orthopedic hand surgery. Laterality plays a role in surgery at every stage, from training and intraoperative performance to patient outcomes and postoperative care. Technological advances such as robotic surgery offer promising solutions to mitigate cognitive asymmetries related to handedness. These tools may offset the effects of handedness. Considering this dimension in the training of future surgeons may contribute to better outcomes and improved working conditions. Copyright © 2025 The Author(s). Published by Elsevier Masson SAS.. All rights reserved

    (In)Visible Hand(s)

    No full text
    In this paper, the author discusses the regulatory role of the state and legal norms, in market economy, especially in so-called transition countries. Legal policy, and other questions of the state and free market economy are here closely connected, because the state must ensure with legal norms that economic processes are not interrupted: only the state can establish the legal basis for a market economy. The free market’s invisible hand is acting in questions such as: what is to be produced, how much is to be produced, for whom it is to be produced, how it is to be produced. During the transition period but also in the establishnig EU, the role of legal norms is much more important then it (is) would be expected: problems of transition are more connected with ethics and psychology, then with legislation.Law and economics, legal norms, (de)regulation, State

    SUPPLEMENTARY_INFORMATION_R_1_OCT_2018 – Supplemental material for Opportunities for antimicrobial stewardship in patients with acute bacterial skin and skin structure infections who are unsuitable for beta-lactam antibiotics: a multicenter prospective observational study

    No full text
    Supplemental material, SUPPLEMENTARY_INFORMATION_R_1_OCT_2018 for Opportunities for antimicrobial stewardship in patients with acute bacterial skin and skin structure infections who are unsuitable for beta-lactam antibiotics: a multicenter prospective observational study by Jonathan A.T. Sandoe, Kordo Saeed, Achyut Guleri, Kieran S. Hand, Ryan Dillon, Mike Allen, Amazigom Mayes, Fiona Glen and Armando Gonzalez-Ruiz in Therapeutic Advances in Infectious Disease</p

    GIT versus Baily-Borel compactification for quartic K3 surfaces

    No full text
    Looijenga has introduced new compactifications of locally symmetric va- rieties that give a complete understanding of the period map from the GIT moduli space of plane sextics to the Baily-Borel compactification of the moduli space po- larized K3’s of degree 2, and also of the period map of cubic fourfolds. On the other hand, the period map of the GIT moduli space of quartic surfaces is significantly more subtle. In our paper [LO16] we introduced a Hassett-Keel–Looijenga program for certain locally symmetric varieties of Type IV. As a consequence, we gave a complete conjectural decomposition into a product of elementary birational modifi- cations of the period map for the GIT moduli spaces of quartic surfaces. The purpose of this note is to provide compelling evidence in favor of our program. Specifically, we propose a matching between the arithmetic strata in the period space and suitable strata of the GIT moduli spaces of quartic surfaces. We then partially verify that the proposed matching actually holds
    corecore