1,354,478 research outputs found
Corrigendum
No full textDiagnostic challenges in low-grade central osteosarcoma: a retrospective study
Published online 1 January 2024 at https://boneandjoint.org.uk/Article/10.1302/0301-620X.106B1.BJJ2023-0531.R1 and in Bone Joint J. 2024;106-B(1):
99–106.
The author Costantino Errani’s name was incorrectly given as “Constantino Errani” in the January 2024
published version.
The correct version is now online
ONCOLOGY Diagnostic challenges in low-grade central osteosarcoma
No full textAims Low-grade central osteosarcoma (LGCOS), a rare type of osteosarcoma, often has misleading radiological and pathological features that overlap with those of other bone tumours, thereby complicating diagnosis and treatment. We aimed to analyze the clinical, radiological, and pathological features of patients with LGCOS, with a focus on diagnosis, treatment, and outcomes. Methods We retrospectively analyzed the medical records of 49 patients with LGCOS (Broder’s grade 1 to 2) treated between January 1985 and December 2017 in a single institute. We examined the presence of malignant features on imaging (periosteal reaction, cortical destruction, soft-tissue invasion), the diagnostic accuracy of biopsy, surgical treatment, and oncological outcome. Results Based on imaging, 35 of 49 patients (71.4%) exhibited malignant features. Overall, 40 of 49 patients (81.6%) had undergone a biopsy before en-bloc resection: 27 of 40 patients (67.5%) were diagnosed on the first biopsy, which was more accurate when carried out by open rather than needle biopsy (91.3% vs 35.3% diagnostic accuracy, respectively; p < 0.001). Of the 40 patients treated by en-bloc resection, surgical margins were wide in 38 (95.0%) and marginal in two (5.0%). Furthermore, nine of 49 patients (18.4%) underwent curettage (intralesional margin) without previous biopsy. All patients with a positive margin developed local recurrence. Distant metastases occurred in five of 49 patients (10.2%). The mean five-year overall survival (OS) and distant relapse-free survival (D-RFS) were 89.3% (SD 5.1%) and 85.7% (SD 5.5%), respectively. Univariate analysis showed that the occurrence of distant metastasis was a poor prognostic factor for OS (hazard ratio 11.54, 95% confidence interval (CI) 1.92 to 69.17; p < 0.001). Local recurrence was a poor prognostic factor for D-RFS (HR 8.72, 95% CI 1.69 to 45.0; p = 0.002). Conclusion The diagnosis of LGCOS can be challenging because it may present with non-malignant features and has a low diagnostic accuracy on biopsy. If precisely diagnosed, LGCOS can be successfully treated by surgical excision with wide margins. Cite this article: Bone Joint J 2024;106-B(1):99–106
Distal fibula reconstruction in primary malignant tumours
No full textBackground: Restoration of ankle biomechanics after distal fibula (DF) resection in bone sarcomas can be performed with different techniques. We report the functional and oncological outcomes of a case series; (2) Methods: Ten patients (5 females and 5 males) with a mean age of 27 years (range 10–71) were retrospectively evaluated. Following the resection, different techniques were used to reconstruct the ankle: tibiotalar arthrodesis, residual lateral malleolus fixed to the tibia, non-vascularized or rotational vascularized fibula transposition and intercalary allograft. All complications were recorded, and the functional outcomes were evaluated; (3) Results: The mean follow-up time was 54 months (range, 13–116). Six patients were free of disease while four patients died of disease. All patients had a stable ankle and bone union, which was achieved after a mean of 9.4 months (range 3–20). The mean MSTS Score was 26.7 (range 21–30). Chronic ankle pain and peroneal external nerve palsy were observed. Patients underwent additional surgeries for deep infection and for equinus ankle deformity. No local recurrence was observed. Metastasis occurred in four patients after a mean of 14.7 months (range 2–34); (4) Conclusions: After DF resection, the restoration of ankle biomechanics gives acceptable functional results, but a larger series of patients with long-time follow-up are required to confirm the durability of the reconstruction
All Things Unsettled, Remain
No full textHelen Khal: Gallery One and Beirut in the 1960s is a reflective publication of an exhibition: part archive, as well as a living testament to the late Helen Khal (1923–2009). A polymath, artist, educator, and writer, Khal was also the cofounder of Gallery One, the first modern and contemporary art gallery in Lebanon, which opened its doors to the public in Beirut in 1963.
This publication follows an exhibition initiated by Carla Chammas and curated by Chammas and Rachel Dedman as part of Home Works 8: A Forum on Cultural Practices, which opened its doors at the Sursock Museum, Beirut in October 2019. The exhibition, like the catalogue, detailed Helen's life and practice as a catalytic lens through which to explore the work of a group of artists whom she was close to, in life and in art, including: Chafic Abboud, Yvette Achkar, Etel Adnan, Huguette Caland, Simone Fattal, Farid Haddad, Helen Khal, Saloua Raouda Choucair, Aref El Rayess, and Dorothy Salhab-Kazemi.
From here, the book, co-authored by Chammas, Dedman and Kholeif, seeks to address the exhibition's themes of love, sex, and motherhood, the relationship between visual art and the literary landscape of 1960s and 1970s Beirut, and the galleries and studios in which public collaborations and private kinships were forged.
Taking an intimate approach to a fabled period, Helen Khal: Gallery One and Beirut in the 1960s unfolds a rich picture of the friendships, connections, modes of exchange, common concerns, and differing approaches of some of the best-known and least-remembered artists of the mid-twentieth century in Lebanon
Reconstruction of the pelvic ring in iliac or iliosacral resections: allograft or autograft?
No full textBackground: The necessity to reconstruct the pelvic ring after an iliac or iliosacral resection is still debated. Different reconstructive techniques are available, including autologous and homologous graft and custom-made prosthesis. The aim of this study was to evaluate the functional outcome and complications of patients who underwent resection of iliac bone and part of the sacrum for primary bone tumour and reconstruction with an allograft or autograft. Methods: We retrospectively evaluated 18 patients (10 males and 8 female) with a mean age of 28 years (range 9–56) who were operated between 1992 and 2015. Six patients were reconstructed with an autograft (Group A) and 12 patients with an allograft (Group B). All complications were recorded. At final follow-up, patients with the original reconstruction still in site were functionally evaluated with MSTS Score. Results: Mean follow-up time was 107 months (range 4–221). Two patients (11.1%) had an external hemipelvectomy for local recurrence, and 3 patients died of the disease. Mean MSTS Score was comparable between the two groups 21.7 (range 20–25) in Group A and 19.9 (range 4–28) in Group B. Patients with partial sacral resection had an increased risk of local recurrence and lower MSTS Score [15.5 (range 7–20) vs. 22.2 (range 4–28)]. Conclusions: Biological reconstruction of pelvic ring with autologous or homologous bone graft gives acceptable functional results. However, the decision on how to reconstruct the pelvic ring after iliac resection should be taken on a patient-by-patient basis
Journal d’un chien de Youssef Al-Khal
No full textيجد القارىء هنا ترجمة فرنسية لكتاب يوسف الخال "يوميات كلب"، مع مقدمة تشرح الأهية الأدبية للكتاب وبعض الصعوبات التى واجهها المترجم. والكتاب سيرة ذاتية يروي فيها كلب، بالعامية المشرية، الأيام الأجيرة من حياته. وهذه الاستعارة أغت النص الذي حمل لنا تأملات حول الحياة والموت لا تخلو من الفكاهة حتى فى أشد اللحظات أسئ.We preface here and translate into French a book written in Oriental Arabic. The book is "Yawmiyyat kalb" by YoussofAl—Khal. It has the form ofan autobiography in which a dog is narrating the last 75 days of its life. By using the allegory of a dog, Al—Khal expresses humorously the most profound and gloomy thoughts about life and death.Le recueil ici présenté et traduit a été écrit en dialecte oriental. Sa portée lit- téraire est évidente (empruntant la forme autobiographique, un chien raconte les derniers soixante quinze jours de sa vie), s'y ajoute sa valeur linguistique. II con- stitue une phase importante et mûre dans la promotion de l' arabe dialectal par la production littéraire. Par le recours à l' allégorie d'un vieux chien méditant sur la vie, la jeunesse et la mort, le texte d' Al—Khal s'enrichit de multiples possibilités tout en gardant un brin de gaieté dans ses plus tristes épisodes
The Thursday Murder Club: Launching a megabrand author - a publishing case study
No full textIn 2020, the Christmas book charts in the UK made headlines: Barack Obama’s eagerly awaited autobiography, The Promised Land, was beaten to the top spot by The Thursday Murder Club by Richard Osman, a debut cosy crime novel set in a retirement village. Not only did Osman’s book beat the former US president’s expected bestseller, it also broke records, becoming the fastest-selling debut crime novel of all time. Although Osman has a certain level of fame in the UK from his TV appearances on shows such as Pointless, his celebrity status does not entirely explain the novel’s huge sales. This article tracks the acquisition, publication, and promotion journey of The Thursday Murder Club in order to understand the industry and cultural context of its success and to interrogate the role of celebrity in the creation of author brands. The findings suggest that the unexpected scale of the success of the book owed to a number of factors, including in-depth editing by the novel’s agent, editor, and author to tighten up the plot, an extensive and strategic promotional campaign, the pandemic (which drove interest in the book’s genre and themes), and the quality of the writing. We find that the book’s success was accentuated by Osman’s celebrity status rather than being entirely reliant on it. This research adds to the growing scholarship on celebrity authorship by means of an in-depth case study and provides insight into the processes behind publishing a ‘celebrity’ book and launching a megabrand author
Khal Torabully
No full textKhal Torabully creates poetry and a poetics for those forgotten by history, a theorem and theory which construct a tangible and sensual landscape, allowing for an empathetically shared experience and expressing the dramatic climax of the third phase of accelerated globalization: a project that would be unthinkable without the cultural theory we now have at our disposal in the present surge of globalization. In his poetic and theoretical texts, he has paid a literary tribute to the Coolies, usually from India, but also China and many other countries. Given Torabully’s Mauritian roots, but also the worldwide migration of the Coolies themselves, the world of Coolitude is culturally and linguistically extremely diverse, making the act of translation very relevant and giving it multiple meanings. Literature brings these forgotten lives back to life and allows us to share this experience thanks to its aesthetic force. It traces the movements, which sketch trajectories functioning to this day as palimpsest-like vectors of our own paths and trajectories. The author of Chair Corail, Fragments Coolies breaks the chain of mutual exclusions, replacing it with a type of writing belonging to a wider array of expressive modes which in diasporic situations unleash polylogical and archipelagic imaginaries
Assessing Urban Flooding Extent of the Baunia Khal Watershed in Dhaka, Bangladesh
No full textDue to the gradual encroachment of natural drainage channels (also known as khals) and the poor management of drainage infrastructures, any rainfall of higher intensity for a few hours causes urban flooding in Dhaka, Bangladesh, hindering the daily lives of city dwellers, especially in slum areas. The Intensity–Duration–Frequency (IDF) curves with return intervals of 2, 5, 10, 25, 50, and 100 years were estimated for a 3 h duration of rainfall using the Gumbel statistical method to assess urban flooding extent around the Baganbari slum within the Baunia Khal watershed. The spatial land use changes of the Baunia Khal were also delineated through the analysis of the areal changes of the khal from 2004 to 2020. The area of the khal was found to be 7.00 km2, 2.17 km2 and 0.41 km2 for the years 2004, 2010, and 2020, respectively. It appears that a gradual massive areal decrease of the khal (impervious land segment) was in progress during this period for high encroachments driven by various governmental agencies and other private entities’ urban developmental projects. The runoff coefficient was computed as 0.76 based on the existing land use pattern, slope, and soil type of the study area. The average runoff generated from the catchment was estimated using the rational method and was 103.41 m3/hr. The drainage length was calculated as 9.1 km using the Kirpich method, whereas the present drainage length was reported as only 6.95 km. The multiple rainfall intensities with return periods of 2, 5, 10, 25, 50, and 100 years were also applied to replicate a heightened extent of urban flooding in the Baunia Khal watershed. The study suggests that the depth, length and width of the Baunia Khal need to increase to hold the generated runoff to manage urban flooding around the Baunia Khal watershed
Phytoplankton Community of Boalia Khal Tributary of the Halda River, Chattogram, Bangladesh
No full textBoalia Khal is one of the important tributaries of the River Halda. The productivity of the Boalia Khal tributary of the Halda River mainly depends on the phytoplankton diversity. A study was conducted for two years period from January 2017 to December 2018 to identify the phytoplankton community of the Boalia Khal tributary. A total of 61 species of phytoplankton under 37 genera belonging to 8 classes were recorded. The dominant group of phytoplankton was 25 species of Diatoms (40.98 %) followed by 18 species of Green Algae (29.5 %), 9 species of Euglenophytes (14.75 %), 7 species of Blue Green Algae (11.48 %), and 2 species of Dinoflagellates (3.28 %). Therefore, the Boalia Khal is a productive ecosystem with a diverse group of phytoplankton species
- …
