169,852 research outputs found
Autonomic cardiovascular function in high-altitude Andean natives with chronic mountain sickness
No full textAutonomic cardiovascular function in high-altitude Andean natives with chronic mountain sickness.
C. KEYL, 1 A. SCHNEIDER, 1 A. GAMBOA, 2 L. SPICUZZA, 3 N. CASIRAGHI, 4 ́ N-VELARDE, 2 AND L. BERNARDI 4, A. MORI, 5 R. TAPIA RAMIREZ, 2 F. LEO
1 Department of Anesthesiology, University Medical Center, 93042 Regensburg, Germany; 2 Department of Physiological Sciences, Universidad Cayetano Heredia, Lima 700, Peru; 3 Institute of Respiratory Diseases, University of Catania, 95124 Catania, Italy; 4 Department of Internal Medicine and Institute of Hematology, and 5 Department of Pathology, University of Pavia and Istituto di Ricovero e Cura a Carattere Scientifico San Matteo, 27100 Pavia, Italy
We evaluated autonomic cardiovascular regulation in subjects with polycythemia and chronic mountain sickness (CMS) and tested the hypothesis that an increase in arterial oxygen saturation has a beneficial effect on arterial baroreflex sensitivity in these subjects. Ten Andean natives with a Hct >65% and 10 natives with a Hct 65% showed an increased incidence of CMS compared with subjects with Hct <60%. Spontaneous baroreflex sensitivity was significantly lower in subjects with high Hct compared with the control group. The effects of supplemental oxygen or modification of the breathing pattern on autonomic function were as follows: 1) heart rate decreased significantly after both maneuvers in both groups, and 2) spontaneous baroreflex sensitivity increased significantly in subjects with high Hct and did not differ from subjects with low Hct. Temporary slow-frequency breathing may provide a beneficial effect on the autonomic cardiovascular function in high-altitude natives with CMS
Figure 4 in Identification of Chironomus (Chironomus) melanescens Keyl, 1962 in North America
No full textFigure 4. Polytene chromosomes of C. melanescens. Chromosome arms on Keyl (1962) system (A-G); nucleolus (N); Balbiani rings (BR).Published as part of Martin, Jon, 2015, Identification of Chironomus (Chironomus) melanescens Keyl, 1962 in North America, pp. 40-44 in CHIRONOMUS Journal of Chironomidae Research 28 (28) on page 43, DOI: 10.5324/cjcr.v0i28.1898, http://zenodo.org/record/799473
Draft Genome Sequence of the Thermophilic Acetogen <i>Moorella humiferrea</i> DSM 23265
No full textABSTRACT
Moorella humiferrea
is an endospore-forming, anaerobic, and thermophilic bacterium which was isolated from a terrestrial hydrothermal spring.
M. humiferrea
is able to use humic acid or 10-anthraquinone-2,6-disulfonate as an electron-shuttling compound for growth and Fe(III) reduction. The genome has a size of 2.629 Mb and contains 2,668 predicted protein-coding genes.
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Sleep-related hypoxaemia and excessive erythrocytosis in Andean high-altitude natives
No full textSleep-related hypoxaemia and excessive erythrocytosis in Andean
high-altitude natives.
L. Spicuzza * , N. Casiraghi # , A. Gamboa } , C. Keyl z , A. Schneider z , A. Mori § , F. Leon-Velarde } , G.U. Di Maria * , L. Bernardi #
*Dept of Internal Medicine and Medical Specialities, University of Catania, # Dept of Internal Medicine and § Pathology, IRCCS S. Matteo and University of Pavia, Italy. } University Cayetano Heredia, Lima, Peru. z Dept of Anaesthesiology, University of Regensburg, Germany.
To determine whether nocturnal hypoxaemia contributes to the excessive erythrocytosis (EE) in Andean natives, standard polysomnographies were performed in 10 patients with EE and in 10 controls (mean haematocrit 76.6 +/- 1.3% and 5.4 +/- 0.8%, respectively) living at an altitude of 4,380 m. In addition, the effect of O2 administration for 1 h prior to sleep, and the relationship between the hypoxic/hypercapnic ventilatory response and the apnoea/hypopnoea index (AHI) during sleep were studied. Awake arterial oxygen saturation (Sa,O2) was significantly lower in patients with EE than in controls (83.7 +/- 0.3% versus 85.6 +/- 0.4%). In both groups, the mean Sa,O2 significantly decreased during sleep (to 80.0 +/- 0.8% in EE and to 82.8 +/- 0.5% in controls). The mean Sa,O2 values remained significantly lower in patients with EE than in controls at all times of the night, and patients with EE spent significantly more time than the controls with an Sa,O2 of <80%. There were no differences between the two groups in the number and duration of the apnoeas/hypopnoeas. None of these variables were affected by O2 administration. In both groups the AHI positively correlated with the hypercapnic ventilatory response. Andean natives undergo minor respiratory disorders during sleep. The reduction in oxygen saturation found in subjects with excessive erythrocytosis was small, yet consistent and potentially important, as it remained below the threshold known for the increase in erythropoietin stimulation. This may be an important factor promoting erythropoiesis, but its relevance needs to be further explored
Sinusoidal neck suction for evaluation of baroreflex sensitivity during desflurane and sevoflurane anesthesia
No full text
Cardiocirculatory coupling during sinusoidal baroreceptor stimulation and fixed-frequency breathing
No full textFIGURES 30–36 in A new record of Chironomus (Chironomus) acidophilus Keyl (Diptera, Chironomidae) from the Uzon volcanic caldera (Kronotsky Reserve, Kamchatka Peninsula, Russia), its karyotype, ecology and biology
No full textFIGURES 30–36. Larva of C. acidophilus Keyl. 30—frontal apotome; 31—antenna; 32—seta of labrum S I; 33—pecten epipharyngis; 34—premandible; 35—mandible; 36—mentum and ventromental plates.Published as part of Orel, Oksana V., Lobkova, Ludmila E., Zhirov, Sergey V. & Petrova, Ninel A., 2015, A new record of Chironomus (Chironomus) acidophilus Keyl (Diptera, Chironomidae) from the Uzon volcanic caldera (Kronotsky Reserve, Kamchatka Peninsula, Russia), its karyotype, ecology and biology, pp. 177-192 in Zootaxa 3981 (2) on page 184, DOI: 10.11646/zootaxa.3981.2.2, http://zenodo.org/record/23443
Peripheral arterial vascular function at altitude: sea-level natives versus Himalayan high-altitude natives
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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