244 research outputs found
The Gospel of Freedom
No full textWilbur H. Siebert published his landmark study of the Underground Railroad in 1898, revealing a secret system of assisted slave escapes. A product of his time, Siebert based his research on the accounts of northern white male abolitionists. While useful in understanding the northern boundaries of the slaves\u27 journey, Siebert\u27s account leaves out the complicated narrative of assistance below the Mason-Dixon Line. In The Gospel of Freedom: Black Evangelicals and the Underground Railroad, author Alicestyne Turley positions Kentucky as a crucial pass through territory for escaping slaves and addresses the important contributions of white and black antislavery southerners who united to form organized networks to assist slaves in the Deep South. Drawing on family history and lore as well as a large range of primary sources, Turley shows how free and enslaved African Americans directly influenced efforts to physically and spiritually resist slavery and how slaves successfully developed their own systems to help others who were enslaved below the Mason-Dixon Line. Illuminating the roles of these black freedom fighters, Turley questions the validity of long-held conclusions based on Siebert\u27s original work and suggests new areas of inquiry for further exploration. The Gospel of Freedom seeks to fill the historical gaps and promote the lost voices of the Underground Railroad.https://uknowledge.uky.edu/upk_cr/1019/thumbnail.jp
TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan.
No full textTGF-beta is a potent stimulator of motility in a variety of cell types. It has recently been shown that hyaluronan (HA) can directly promote locomotion of cells through interaction with the HA receptor RHAMM. We have investigated the role of RHAMM and HA in TGF-beta-stimulated locomotion and show that TGF-beta triggers the transcription, synthesis and membrane expression of the RHAMM receptor and the secretion of HA coincident with the induction of the locomotory response. This was demonstrated by both incubating cells with exogenous TGF-beta1 and by stimulating the production of bioactive TGF-beta1 in tumor cells transfected with TGF-beta1 under the control of the metallothionein promoter. TGF-beta1-induced locomotion was suppressed by antibodies that prevented HA/RHAMM interaction, using polyclonal antibodies to either RHAMM fusion protein or RHAMM peptides, or mAbs to purified RHAMM. Peptides corresponding to the HA-binding motif of RHAMM also suppressed TGF-beta1-induced increases in motility rate. Spontaneous locomotion of fibrosarcoma cells was blocked by neutralizing secreted TGF-beta with panspecific TGF-beta antibodies and by inhibition of TGF-beta1 secretion with antisense oligonucleotides. Polyclonal anti-RHAMM fusion protein antibodies and peptide from the RHAMM HA-binding motif also suppressed the spontaneous motility rate of fibrosarcoma cells. These data suggest that fibrosarcoma cell locomotion requires TGF-beta, and the pathway by which TGF-beta stimulates locomotion uses the HA receptor RHAMM and HA.PT: J; CR: ALLEN JB, 1990, J EXP MED, V171, P231 ANZANO MA, 1985, MOL CELL BIOL, V5, P242 BARNARD JA, 1990, BIOCHIM BIOPHYS ACTA, V1032, P79 BASSOLS A, 1988, J BIOL CHEM, V263, P3039 BRAY BA, 1991, AM REV RESPIR DIS, V143, P284 CHAN BM, 1992, CELL, V68, P1051 CHEN JK, 1987, P NATL ACAD SCI USA, V84, P5287 CULTY M, 1990, J CELL BIOL 1, V111, P2765 DALAL BI, 1993, AM J PATHOL, V143, P381 DANIELPOUR D, 1989, J CELL PHYSIOL, V138, P79 DELPECH B, 1981, J NEUROCHEM, V36, P855 DERYNCK R, 1987, CANCER RES, V47, P707 DOEGE K, 1987, J BIOL CHEM, V262, P17757 FASSEN AE, 1992, J CELL BIOL, V116, P521 FAVA RA, 1991, J EXP MED, V173, P1121 GOETINCK PF, 1987, J CELL BIOL, V105, P2403 GOUGH NM, 1988, ANAL BIOCHEM, V173, P93 HARDWICK C, 1992, J CELL BIOL, V117, P1343 HEINE UI, 1987, J CELL BIOL, V105, P286 HEINO J, 1989, J BIOL CHEM, V264, P380 HELDIN P, 1989, BIOCHEM J, V258, P919 HOOK M, 1984, ANNU REV BIOCHEM, V53, P847 HURTA RAR, 1991, J BIOL CHEM, V266, P24097 HYNES RO, 1992, CELL, V69, P11 KAHARI VM, 1991, J BIOL CHEM, V266, P10608 KHALIL N, 1989, J EXP MED, V170, P727 KHALIL N, 1991, CIBA F SYMP, V157, P194 KIMATA K, 1983, CANCER RES, V43, P1347 KLEINSOYER C, 1989, ARTERIOSCLEROSIS, V9, P147 KRUSIUS T, 1987, J BIOL CHEM, V262, P13120 LAEMMLI UK, 1970, NATURE, V227, P680 LIOTTA LA, 1988, CANCER SURV, V7, P631 MADRI JA, 1988, J CELL BIOL, V106, P1375 MASSAGUE J, 1990, ANNU REV CELL BIOL, V6, P597 MCCARTHY JB, 1992, IN PRESS CRC CRIT RE MCCLARTY GA, 1987, BIOCHEM BIOPH RES CO, V145, P1276 MOORADIAN DL, 1992, J NATL CANCER I, V84, P523 NEAME PJ, 1986, J BIOL CHEM, V261, P3519 NETTELBLADT O, 1989, AM REV RESPIR DIS, V139, P759 NUGENT MA, 1992, J BIOL CHEM, V267, P21256 PARTIN AW, 1988, CANCER RES, V48, P6050 PARTIN AW, 1989, P NATL ACAD SCI USA, V86, P1254 PERIDES G, 1989, J BIOL CHEM, V264, P5981 PEROTTI D, 1991, CANCER RES, V51, P5491 PIERCE GF, 1989, P NATL ACAD SCI USA, V86, P2229 POSTLETHWAITE AE, 1987, J EXP MED, V165, P251 REIBMAN J, 1991, P NATL ACAD SCI USA, V88, P6805 ROBERTS AB, 1990, HDB EXPT PHARM, V95, P419 SAMUEL SK, 1992, EMBO J, V11, P1599 SATO Y, 1988, J CELL BIOL, V107, P1199 SCHOR SL, 1989, IN VITRO CELL DEV B, V25, P737 SCHWARZ LC, 1990, GROWTH FACTORS, V3, P115 STAMENKOVIC I, 1991, EMBO J, V10, P343 STOKER M, 1991, BIOCHIM BIOPHYS ACTA, V1072, P81 THOMAS L, 1992, J CELL BIOL, V118, P971 TOOLE BP, 1979, P NATL ACAD SCI USA, V76, P6299 TOOLE BP, 1989, CIBA F SYMP, V143, P138 TOOLE BP, 1990, CURR OPIN CELL BIOL, V2, P839 TURLEY EA, 1985, CANCER RES, V45, P5098 TURLEY EA, 1985, EXP CELL RES, V161, P17 TURLEY EA, 1987, BIOCHEMISTRY-US, V26, P2997 TURLEY EA, 1989, EXP CELL RES, V181, P340 TURLEY EA, 1991, ADV DRUG DELIVER REV, V7, P257 TURLEY EA, 1991, J CELL BIOL, V112, P1041 WAHL SM, 1987, P NATL ACAD SCI USA, V84, P5788 WELSH DR, 1991, P NATL ACAD SCI USA, V87, P7678 YAMADA KM, 1990, CANCER RES, V50, P4485 YAMAGUCHI Y, 1990, NATURE, V346, P281 YANG BH, 1993, J BIOL CHEM, V268, P8617; NR: 69; TC: 73; J9: J CELL BIOL; PG: 10; GA: ME817Source type: Electronic(1
The school luncheon
No full textby Ava B. Milam, Anna M. Turley, Helen Cowgill.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Electronic reproduction. Salem, Or. : State Library of Oregon, 2023 Electronic reproduction from print version OrMode of access: Internet from the Oregon Government Publications Collection.Text in English
The Rise and Fall of Mark Hofmann
No full textJoin us on March 30, 2022 at 7:00 p.m. in room 101 to hear from Richard E. Turley Jr. as he discusses Mark Hofmann’s rise and fall. In 1980, Mark Hofmann was an obscure student at Utah State University. One morning that year, he walked into the university library with a discovery that helped catapult him to fame as a document dealer. Over the next five years, his document discoveries expanded from those related to Latter-day Saint and Utah history to stunning pieces of Americana. Ultimately, he hoped to sell the Oath of a Freeman, purportedly the earliest printed document in America, to the Library of Congress for 1.5 million dollars. Closer to home, he hinted that he was on the trail of the Holy Grail of Latter-day Saint history, the lost 116 pages of the Book of Mormon. Then in October 1985, three bombs went off in the Salt Lake Valley, the first fatally injuring a businessman who was a Hofmann client, the second killing the wife of the businessman\u27s associate, and the third nearly killing Hofmann himself. The ensuing investigation proved that Hofmann was the serial bomber and that virtually all of his key discoveries were forgeries. He was sentenced to prison for his crimes, with a recommendation that he never be paroled.
Richard E. Turley Jr. is an award-winning historian who served for twenty-two years as the managing director of the Church History Department of The Church of Jesus Christ of Latter-day Saints. He is the author of numerous books on Latter-day Saint and Western U.S. history, including Victims: The LDS Church and the Mark Hofmann Case
Consumption outside the market: an ethnography of consumer resistance among football fans
No full textThis study analysed football fandom utilising an ethnographic approach. Football fandom was selected as a research site for the study because it offered scope to explore for the presence of non-traditional forms of cultural capital (Bourdieu 1984).
It also offered scope to explore the extent to which fandom was a form of sacred consumption (Belk et a1 1989). Ethnography was selected as an appropriate methodology for several reasons. It provided the opportunity to develop a holistic perspective on fandom and it further provided scope to utilise an emergent design approach in the development of a conceptual understanding of fandom. What emerged fiom the ethnographic investigation of two separate football fan communities was that consumers experience and maintain a sense of the sacred by operating their own unofficial markets in competition with the official market in fanrelated goods and services. They also maintain localised systems of cultural capital which allow them to socially construct and maintain a sense of hierophany within their own communities (Belk et a1 1989), in opposition to the homogenised fan identity proffered by the official market. These systems of cultural capital not only allow fans to experience the sacred but also facilitate their sense of relationship with like-minded others in self-selecting communities of shared taste
Doing it differently: Engaging interview participants with imaginative variation
No full textImaginative variation was identified by Husserl (1936/1970) as a phenomenological technique for the purpose of elucidating the manner in which phenomena appear to consciousness. Briefly, by engaging in the phenomenological reduction and using imaginative variation, phenomenologists are able to describe the experience of consciousness, having stepped outside of the natural attitude through the epochē. Imaginative variation is a stage aimed at explicating the structures of experience, and is best described as a mental experiment. Features of the experience are imaginatively altered in order to view the phenomenon under investigation from varying perspectives. Husserl argued that this process will reveal the essences of an experience, as only those aspects that are invariant to the experience of the phenomenon will not be able to change through the variation.
Often in qualitative research interviews, participants struggle to articulate or verbalise their experiences. The purpose of this article is to detail a radical and novel way of using imaginative variation with interview participants, by asking the participants to engage with imaginative variation, in order to produce a rich and insightful experiential account of a phenomenon. We will discuss how the first author successfully used imaginative variation in this way in her study of the erotic experience of bondage, discipline, dominance & submission, and sadism & masochism (BDSM), before considering the usefulness of this technique when applied to areas of study beyond sexuality
Exploring sexual dimorphism of the modern human talus through geometric morphometric methods
No full textSex determination is a pivotal step in forensic and bioarchaeological fields. Generally, scholars focus on metric or qualitative morphological features, but in the last few years several contributions have applied geometric-morphometric (GM) techniques to overcome limitations of traditional approaches. In this study, we explore sexual dimorphism in modern human tali from three early 20th century populations (Sassari and Bologna, Italy; New York, USA) at intra- and interspecific population levels using geometric morphometric (GM) methods. Statistical analyses were performed using shape, form, and size variables. Our results do not show significant differences in shape between males and females, either considering the pooled sample or the individual populations. Differences in talar morphology due to sexual dimorphism are mainly related to allometry, i.e. size-related changes of morphological traits. Discriminant function analysis using form space Principal Components and centroid size correctly classify between 87.7% and 97.2% of the individuals. The result is similar using the pooled sample or the individual population, except for a diminished outcome for the New York group (from 73.9% to 78.2%). Finally, a talus from the Bologna sample (not included in the previous analysis) with known sex was selected to run a virtual resection, followed by two digital reconstructions based on the mean shape of both the pooled sample and the Bologna sample, respectively. The reconstructed talus was correctly classified with a Ppost between 99.9% and 100%, demonstrating that GM is a valuable tool to cope with fragmentary tali, which is a common occurrence in forensic and bioarchaeological contexts.</div
Murray City Fire Department, 2001
No full textGroup photo of the Murray Fire Department crew, on and around one of the Fire Department\u27s large trucks. Pictured: Jon Jastram, Matt Boulden, Marilyn Madsen, Mike Estrada, Andy Walkingshaw, Jesse Valenzuela, Phil Roberts, Chief Gil Rodriguez, Paul Adams, Blair Camp, Mike Dykman, Jack Snow, Randy Willden, Laura Lloyd, Glenae Turley, Chad Pascua, Kendall Baird, Jeff Ellis, Art Cracraft, Kent Swensen, Paul Krueger, Jerry Bilanzich, Shane Stratton, Chris Pendleton, Steve Ellefsen, Bob Smith, Pat Killion, Joe Beard, Jeff Thornley, Paul Mapes, Kevin Potter, Joe Treadwell, Kelly Farrington, Amy Fisher, Russ Jensen, Rex Stembridge, Dave Florin, Paul Adams, Jon Harris, Brad Freeman, Russ Blank, Kevin Divine, Scott White, Jon Grangroth, Jeremy Shoemaker, Statt Berger, Jennifer Litster, Kevin Fellion, Jeff Griffith, Dave Shaw, Jason Jone
Carta informando sobre el estado de las misiones de California, 1776 diciembre 25
No full textCarta informando sobre el estado de las misiones de California, específicamente las Misiones de San Diego, San Juan Capistrano y Santa Clara, y la fuerza militar según noticias que el autor ha recibido de correspondencia anterior. El autor señala la suspensión de la reconstrucción de la Misión de San Diego en ruinas después de la revuelta, recomendando clemencia para los líderes de la rebelión. El autor también solicita el establecimiento de la Misión Santa Clara cerca del Presidio de San Francisco, indicando los suministros necesarios para la fundación. —— Letter informing on the state of the California missions, specifically Missions San Diego, San Juan Capistrano, and Santa Clara, and the military force per news the author has received from prior correspondence. The author notes the suspension of the reconstruction of the ruined Mission of San Diego after the revolt, recommending clemency for the leaders of the rebellion. The author also requests the establishment of Mission Santa Clara near the Presidio of San Francisco, indicating the necessary supplies for the founding. 2 f. (4 p.
The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth.
No full textEstrogen receptor alpha (ERalpha) plays an important role in breast cancer. Upregulation of HIF-1alpha in ER(alpha)-positive cancers suggests that HIF-1alpha may cooperate with ERalpha to promote breast cancer progression and consequently affect breast cancer treatment. Here, we show the histone demethylase JMJD2B is regulated by both ERalpha and HIF-1alpha, drives breast cancer cell proliferation in normoxia and hypoxia, and epigenetically regulates the expression of cell cycle genes such as CCND1, CCNA1, and WEE1. We also show that JMJD2B and the hypoxia marker CA9 together stratify a subclass of breast cancer patients and predict a worse outcome of these breast cancers. Our findings provide a biological rationale to support the therapeutic targeting of histone demethylases in breast cancer patients
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