1,721,189 research outputs found
Comparative genomics of pathogenic fungi through sequence homology and phylogenetic similarities / Kenneth Tan Lee Shean
No full textFungal pathogenicity is one of the most vigorously tackled ecological and medicinal issues facing many scientists. The emergence of DNA sequencing had allowed massive genome sequencing projects of many important and most fatal pathogenic fungi in the world, coupling with upstream bioinformatics analysis which includes genome assembly and genome annotation had resulted in publicly available datasets that can be utilized for applied bioinformatics research. This study involves building of an aggregate Fungal Pathogenicity-related gene database with 5,183 protein sequences from PHI-base, 921,174 protein sequences from Carbohydrate-Active enZYme Database, and 2,058 protein sequences from Database of Virulence Factors in Fungal Pathogens. Local database was created using makeblastdb within NCBI-BLAST+ application and homology search of protein sequences of 86 fungal species was carried out with BLASTP resulting in identification of potential common pathogenic genes between fungus in study, also to identify potential biomarkers and understanding phylogenetic relationships of pathogenic fungi. The database can be utilized as an aggregated application for fungal pathogenic genes annotation that contributes to a wider research community
Supplementary Material, Relationship_Readiness_SINGLES_OSM_1.30.18-1 – Commitment Readiness and Relationship Formation
No full textSupplementary Material, Relationship_Readiness_SINGLES_OSM_1.30.18-1 for Commitment Readiness and Relationship Formation by Benjamin W. Hadden Christopher R. Agnew and Kenneth Tan in Personality and Social Psychology Bulletin</p
Supplementary Material, hadden_online_appendix – Commitment Readiness and Relationship Formation
No full textSupplementary Material, hadden_online_appendix for Commitment Readiness and Relationship Formation by Benjamin W. Hadden Christopher R. Agnew and Kenneth Tan in Personality and Social Psychology Bulletin</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Supplemental Material, SPPS829060_suppl_mat - It’s About Time: Readiness, Commitment, and Stability in Close Relationships
No full textSupplemental Material, SPPS829060_suppl_mat for It’s About Time: Readiness, Commitment, and Stability in Close Relationships by Christopher R. Agnew, Benjamin W. Hadden, and Kenneth Tan in Social Psychological and Personality Science</p
Commitment_Desirability_Scale_Development_and_Validation_-_OSM – Supplemental material for Seeking and Ensuring Interdependence: Desiring Commitment and the Strategic Initiation and Maintenance of Close Relationships
No full textSupplemental material, Commitment_Desirability_Scale_Development_and_Validation_-_OSM for Seeking and Ensuring Interdependence: Desiring Commitment and the Strategic Initiation and Maintenance of Close Relationships by Kenneth Tan, Christopher R. Agnew and Benjamin W. Hadden in Personality and Social Psychology Bulletin</p
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Tan_OnlineAppendix – Supplemental material for Seeking and Ensuring Interdependence: Desiring Commitment and the Strategic Initiation and Maintenance of Close Relationships
No full textSupplemental material, Tan_OnlineAppendix for Seeking and Ensuring Interdependence: Desiring Commitment and the Strategic Initiation and Maintenance of Close Relationships by Kenneth Tan, Christopher R. Agnew and Benjamin W. Hadden in Personality and Social Psychology Bulletin</p
Inter-phyla comparative genomics of plant pathogenic fungus reveals genomics similarity and copy number variations / Kenneth Tan Lee Shean
Get PDFThe impact of plant pathogenic fungus towards the industry of agriculture causes massive destruction of crops worldwide and thus stirring interest around the world for research in these plant pathogenic funguses. The vast development of sequencing technologies enabled many public efforts to decipher the genomics information about these funguses and example of such effort is the Fungal Genome Initiative (FGI) by Broad Institute. By using public genomics and annotation data from FGI for four different fungus species from two different phyla, inter-phyla comparative genomics between the fungus species revealed important common features of plant pathogenic funguses. Inter-Phyla comparative genomics results showed that there are 1,388 homologous protein-coding genes between Basidiomycota and Ascomycota. Also done was discovery of candidate protein-coding genes from both pathogen-host interaction-related genes and carbohydrate-active enzymes, which are known as protein-coding genes that are related to fungus pathogenicity. A total of 159 common candidate protein-coding PHI-base genes and 64 common candidate protein-coding genes for carbohydrate-active enzymes were identified between fungus from Basidiomycota and Ascomycota. Genes Copy Number Variation was also observed in both pathogenicity related genes discovery, with 5 candidate PHI-related genes and 3 candidates CAZy showed to have variation in terms of genes copy number. Also discovered is the significant difference in total number of pathogenicity genes between Ascomycetes and Basidiomycetes where Ascomycetes is found to have more copy number of pathogenicity-related genes thatn Basdiomycetes. This research could lead to development of broad-spectrum antifungal solution for the agricultural industry by targeting the common genes identified
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