475 research outputs found
Prevalence and multiple predictors of left atrial low voltage in paroxysmal and non-paroxysmal atrial fibrillation patients undergoing ablation: a systematic review and meta-analysis
No full textAims In the left atrium (LA), low-voltage areas (LVAs) detected at electroanatomic mapping in patients with atrial fibrillation (AF) are considered expression of atrial cardiomyopathy (AtCM). This meta-analysis aims at assessing the prevalence and predictors of LVAs in a larger AF population undergoing catheter ablation. Methods and results Studies comparing patients undergoing LA ablation with vs. those without LVAs were included. Meta-analyses were conducted to estimate the prevalence and odds ratios (ORs) for LVAs. Twenty-two studies with 5278 patients were included. Low-voltage areas were present both in paroxysmal (28%) and non-paroxysmal (41%) patients. The strongest predictors of LVA presence were: age > 65 years (OR 3.41), CHA2DS2-VASc score (OR 3.29), non-paroxysmal AF (OR 3.19), NT-proBNP > 365pg/mL (OR 2.47), female sex (OR 2.40), E/e′ ratio (OR 2.31), eGFR < 60mL/min/m2 (OR 2.28), and LA volume indexed > 34mL/m2 (OR 1.98). Comorbidities were also predictors but with lower ORs. In subgroup analysis, female sex (OR 3.90) was a predictor only in non-paroxysmal, while LA diameter (OR 2.51) and body mass index (BMI; OR 1.85) positively correlated only in paroxysmal AF. Meta-regression analysis showed that non-paroxysmal AF and age were independently and significantly associated with a greater reduction in BMI in patients with compared to those without LVAs. Conclusion Low-voltage areas can be present in both paroxysmal and non-paroxysmal AF, and can be predicted by multiple clinical, echocardiographic, and biomarker variables. The impact of female sex, LA diameter, and BMI on LVA presence varies according to the type of AF
HRS/EHRA expert consensus on the monitoring of cardiovascular implantable electronic devices (CIEDs): description of techniques, indications, personnel, frequency and ethical considerations
No full textThis document represents expert consensus concerning the Monitoring of Cardiovascular Implantable Electronic Devices (CIEDs).The views expressed are of the international writing group consisting of seven cardiac electrophysiologists representing the Heart Rhythm Society (HRS), six from the European Heart Rhythm Association (EHRA) as well as one heart failure specialist representing the Heart Failure Society of America and another from the Heart Failure Association of the European Society of Cardiology. Members from our writing group also represented the American College of Cardiology (Kenneth A. Ellenbogen, MD), the European Society of Cardiology (Silvia G. Priori, MD, PhD), and the American Heart Association (David L. Hayes, MD). The topic covered by this document includes the monitoring of CIEDs with a description of the technology, indications for use, personnel involved in monitoring and the frequency and types of monitoring events. Also covered are issues in regard to data management, regulatory environments, reimbursement and ethical considerations in respect to device inactivation. This statement summarizes the opinion of the writing group members based on their own experience in treating patients, as well as a review of the literature, and is directed to all health care professionals, health care institutions, CIED manufacturers and governmental, reimbursement and regulatory bodies who are involved in the care of patients with CIEDs.When using or considering the guidance given in this document, it is important to remember that the ultimate judgment regarding care of a particular patient must be made by the health care provider and patient in light of all the circumstances presented by that patient
A Partnership for Change Forged in the Steel City: Michael Musmanno & Henry Ellenbogen
No full textIn 1930 author R.L. Duffus, in article entitled “Is Pittsburgh Civilized?” characterized the city as being under the control of a clique of Scots-Irish big businessmen. While this was true at the moment Duffus was writing, the winds of change were blowing. By 1935, the city’s diverse ethnic and racial minorities had jelled together into a durable coalition that moved Pittsburgh from the Republican to the Democratic column. Exemplars of this change were two very different young lawyers who first came into prominence in the late 1920s – Michael A. Musmanno and Henry Ellenbogen: one Italian and the other Jewish, united in a common purpose. Both of them liberals, they eventually became associated with the New Deal, sharing a strong pro-labor bent. They would cooperate closely over the course of their long careers. The first instance of this cooperation came in 1929 at the start of their public lives with their joint effort to end Pennsylvania’s Coal and Iron Police system. Musmanno, fresh from his work as a member of the Sacco & Vanzetti defense team, had recently been elected to Pennsylvania’s State House, representing its 12th legislative district. Ellenbogen was working at the time as General Counsel for Pittsburgh’s newly created branch of the American Civil Liberties Union. In this effort, these two men took on Pittsburgh’s, and by extension Pennsylvania’s, power elite. While both men eventually went on to distinguished careers in public life, this initial fight would always be a touchstone for each of them. This paper looks at their partnership in this effort, how it worked, and how it was a harbinger of the major political shift that was soon to take place in Pittsburgh’s politics
Changes in ecological distribution and socioeconomic composition of black-white marital unions, 1960-1970 an empirical analysis, 1975
No full textThis study presents the results of an examination of demographic and socio-economic trends associated with interracial unions in the United States during the recent 1960-1970 decade. The number of persons in interracial unions still represents much less than one percent of the total married population. Yet, over the past ten years or so, there has been an increase in the prevalence of such marital unions between blacks and whites�to a greater extent than non-mixed unions. Therefore, the investigation of this subpopulation is important and useful, perhaps as an indicator of race relations in this country since marriage not only represents an intimate dyad in American society, but is generally considered to be based on similar socio-economic characteristics as well as prior intensive interaction
Prospects for new program
No full textThis document states that the author has just finished with the Kinky Friedman tour and putting together a proposal for another project
Cardiac Resynchronization Therapy Location Matters⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.
No full textIntegrated heart failure management in the patient with heart failure caused by left ventricular systolic dysfunction.
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