6,294 research outputs found

    Is it only humans that count from left to right?

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    We report that adult nutcrackers (Nucifraga columbiana) and newborn domestic chicks (Gallus gallus) show a leftward bias when required to locate an object in a series of identical ones on the basis of its ordinal position. Birds were trained to peck at either the fourth or sixth element in a series of 16 identical and aligned positions. These were placed in front of the bird, sagittally with respect to its starting position. When, at test, the series was rotated by 908 lying frontoparallel to the bird’s starting position, both species showed a bias for identifying selectively the correct position from the left but not from the right end. The similarity with the well-known phenomenon of the left-to-right spatially oriented number line in humans is considered

    Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules

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    Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii). After removal of the invariant chain, peptides can be loaded onto class II molecules, a process catalyzed by human leukocyte antigen-DM (HLA-DM) molecules. Here we show that MHC class II compartments consist of two physically and functionally distinct organelles. Newly synthesized MHC class II/Ii complexes were targeted to endocytic organelles lacking HLA-DM molecules, where Ii degradation occurred. From these organelles, class II molecules were transported to a distinct organelle containing HLADM, in which peptides were loaded onto class II molecules. This latter organelle was not directly accessible via fluid phase endocytosis, suggesting that it is not part of the endosomal pathway. Uptake via antigen-specific membrane immunoglobulin resulted however in small amounts of antigen in the HLA-DM positive organelles. From this peptide-loading compartment, class II–peptide complexes were transported to the plasma membrane, in part after transit through endocytic organelles. The existence of two separate compartments, one involved in Ii removal and the other functioning in HLA-DM–dependent peptide loading of class II molecules, may contribute to the efficiency of antigen presentation by the selective recruitment of peptide-receptive MHC class II molecules and HLA-DM to the same subcellular location

    Panelist-Profile, Group-Housed Calf Systems: Kelly Farms

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    This information was presented at the 2011 Calf Symposium organized by the PRO-DAIRY program in the College of Agriculture and Life Sciences at Cornell University. This innovative conference is designed to provide progressive dairy producers and agriservice personnel the opportunity to increase their knowledge of dairy calf group housing systems and feeding technologies. Softcover copies of the entire conference proceedings may be purchased at http://www.ansci.cornell.edu/dm/proceedings_orders.html or by calling (607)255-4285

    "Where is the Conscience of Human Rights?", Monthly Academic Circle of the Department of Social Studies (OUSL), 19th June 2017 at 2.30 p.m. at Faculty of Humanities and Social Sciences, The Open University of Sri Lanka, Nawala

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    Monthly Academic Circle Department of Social Studies (OUSL) Invites You for a Talk and Panel Discussion Topic Where is the Conscience of Human Rights? By Prof. Tobias Kelly, The University of Edinburgh [Tobias Kelly teaches social anthropology at the School of Social and Political Science, University of Edinburgh, and is coeditor of Traitors: Suspicion, Intimacy, and the Ethics of State-Building]. Panelists Dr. Deepika Udagama (Chairperson, Human Rights Commission) Professor Jonathan Spencer ..

    Entanglement and quantity in quantum space - About quantum measurement (II)

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    As a continuation and extension of "quantity in phase space" "quantity in quantum space" is introduced. With that, the disappearing of quantum interference discussed in a previous paper [S. Durr, et al., Nature 395 (1998) 33] is explained in the same spirit as our recent papers [Ren De-Ming, Commun. Theor. Phys. (Beijing, China) 41 (2004) 685, 833].Physics, MultidisciplinarySCI(E)中国科学引文数据库(CSCD)1ARTICLE133-364

    Sneutrino DM in the NMSSM with inverse seesaw mechanism

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    In supersymmetric theories like the Next-to-Minimal Supersymmetric Standard Model (NMSSM), the lightest neutralino with bino or singlino as its dominant component is customarily taken as dark matter (DM) candidate. Since light Higgsinos favored by naturalness can strength the couplings of the DM and thus enhance the DM-nucleon scattering rate, the tension between naturalness and DM direct detection results becomes more and more acute with the improved experimental sensitivity. In this work, we extend the NMSSM by inverse seesaw mechanism to generate neutrino mass, and show that in certain parameter space the lightest sneutrino may act as a viable DM candidate, i.e. it can annihilate by multi-channels to get correct relic density and meanwhile satisfy all experimental constraints. The most striking feature of the extension is that the DM-nucleon scattering rate can be naturally below its current experimental bounds regardless of the higgsino mass, and hence it alleviates the tension between naturalness and DM experiments. Other interesting features include that the Higgs phenomenology becomes much richer than that of the original NMSSM due to the relaxed constraints from DM physics and also due to the presence of extra neutrinos, and that the signatures of sparticles at colliders are quite different from those with neutralino as DM candidate.National Natural Science Foundation of China (NNSFC) [11575053]SCI(E)ARTICLE1

    Classical mechanics and quantum mechanics

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    The Newton equation of motion is derived from quantum mechanics.Physics, MultidisciplinarySCI(E)中国科学引文数据库(CSCD)2ARTICLE5685-6884

    Still the SuperGoon

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    Item located in file hy-dm-parker-milligan-1976-1980-001. Not all items in folder uploaded.The engaging newspaper article refers to a concert featuring Spike Milligan. The author commends Milligan's performance which ensured laughter amongst his audience. The article also mentioned what was to be expected from his appearance whilst also including an array of supporting acts with a mention of Ashley Parker
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