102,148 research outputs found

    Correspondence: a cyber disagreement

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    Policymakers and pundits have been sounding alarms about internet insecurity for years, so the first appearance of anything in International Security (IS) on this topic is a welcomed development. In the fall 2013 issue, Lucas Kello takes the security studies community to task for ignoring cyber perils, while Erik Gartzke argues that cyberwar is of limited political utility.1 Kello writes that “[t]he Clausewitzian philosophical framework misses the essence of the cyber danger and conceals its true significance: the virtual weapon is expanding the range of possible harms between the concepts of war and peace, with important consequences for national and international security” (p. 22). Gartzke counters, “War is fundamentally a political process, as Carl von Clausewitz famously explained. … The internet is generally an inferior substitute for terrestrial force in performing the functions of coercion or conquest” (p. 42). If Kello is right, then the long silence in IS on cybersecurity suggests that scholars have neglected a major transformation in security affairs. If Gartzke is right, then scholars can be forgiven their bemusement with inflated cyber rhetoric

    Supplemental Material - Evolution of explorative and exploitative search strategies in collective foraging

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    Supplemental Material for Evolution of explorative and exploitative search strategies in collective foraging by Ketika Garg, Paul E Smaldino, and Christopher T Kello in Collective Intelligence.</p

    Factors affecting in vitro propagation of cassava (Manihot esculenta Crantz.) Euphorbiaceae, varieties of ‘Kello’ and ‘Qulle’

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    Cassava (Manihot esculenta Crantz.) is a perennial shrub of the Euphorbiaceae family native of eastern tropical South America, grown in the tropics of Africa and Asia for its tuberous roots. Its cultivation is constrained by several problems including the use of cuttings infected with diseases and pests, the lack of high quality seed, low productivity, high heterozygosity, low fertility, poor seed set and seed germination. The objective of this study was to find the optimal conditions for micropropagation of two varieties of cassava released for farmers for the production of high quality planting materials. These include determination of the effect of temperature on bud-break of mother plants, differences in concentrations of salt, sucrose, and thidiazuron (TDZ) in a semi-solid MS medium, pH, two-step MS medium and repeated subcultures. The mean number of shoots per plant for axillary bud-break was highest (10.8) at 26°C for that from ‘Kello’ and 9.8 at 30°C for that from ‘Qulle’. The highest mean number of shoots per explant was obtained on MS medium containing 0.2 mg/L TDZ for both varieties on both semi-solid and two-step MS medium culture system. Maximum mean shoot number was obtained on MS medium of a quarter and full salt strength for ‘Kello’ and ‘Qulle’, respectively. The highest mean number of shoots per explant for ‘Kello’ (4.10) and ‘Qulle’ (2.40) was obtained at pH 5.6 and 6.6, respectively. ‘Kello’ produced 3.70 shoots per explant on MS medium containing 1.5% sucrose. Repeated subculturing of ‘Qulle’ resulted in gradual loss of multiplication rate from the third subculture onwards. The present study contributes to optimization of micropropagation of cassava.Key words/phrases: Liquid medium, Salt strength, Shoot multiplication, Sucrose, TDZ

    Letter, [Author unclear] to Paulina T. Merritt

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    Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.

    Handwritten biographical information on Paulina T. McClung Merritt

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    A handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.

    Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.

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    IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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