2,682 research outputs found
A review of the genus Cephaloscyllium (Chondrichthyes: Carcharhiniformes: Scyliorhinidae) from Taiwanese waters
No full textNakaya, Kazuhiro, Inoue, Shinsuke, Ho, Hsuan-Ching (2013): A review of the genus Cephaloscyllium (Chondrichthyes: Carcharhiniformes: Scyliorhinidae) from Taiwanese waters. Zootaxa 3752 (1): 101-129, DOI: 10.11646/zootaxa.3752.1.
Supplemental material for Evaluation of Montelukast for the Treatment of Children With Japanese Cedar Pollinosis Using an Artificial Exposure Chamber (OHIO Chamber)
No full textSupplemental material for Evaluation of Montelukast for the Treatment of Children With Japanese Cedar Pollinosis Using an Artificial Exposure Chamber (OHIO Chamber) by Kazuhiro Hashiguchi, Kimihiro Okubo, Yoichi Inoue, Hirotaka Numaguchi, Kumi Tanaka, Nobuyuki Oshima, Anish Mehta, Chisato Nishida, Itori Saito, George Philip in Allergy & Rhinology</p
sj-xls-1-inq-10.1177_00469580231219094 – Supplemental material for Study of Factors to Increase the Usage Rate of Generic Drugs in Platelet Aggregation Inhibitors
No full textSupplemental material, sj-xls-1-inq-10.1177_00469580231219094 for Study of Factors to Increase the Usage Rate of Generic Drugs in Platelet Aggregation Inhibitors by Takaaki Suzuki, Mari Iwata, Mika Maezawa, Kiyoka Matsumoto, Mizuki Tanaka, Riko Satake, Misaki Inoue, Yu Yoshida, Kazuhiro Iguchi and Mitsuhiro Nakamura in INQUIRY: The Journal of Health Care Organization, Provision, and Financing</p
Periprosthetic Occult Fractures of the Acetabulum Occur Frequently During Primary THA
No full text金沢大学博士（医学）博士論文要旨Abstract 以下に掲載：Clinical Orthopaedics and Related Research 475(2) pp.484-495 2017. splinger. 共著者：Kazuhiro Hasegawa, Tamon Kabata, Yoshitomo Kajino, Daisuke Inoue, Hiroyuki Tsuchiyathesi
Capacitors
No full textThis webpage is part of a larger site by the author about electronic circuit engineering. This page introduces the reader to capacitors, including the principles behind how they work. Explanations of several different types of capacitors (including Electrolytic, Tantalum, and Mica) are accompanied by detailed color illustrations of the concepts
Abstract 3611: Proteasome subunit PSMD1 participates in p53 degradation and regulates proliferation of breast cancer cells
No full textAbstract
Breast cancer is the most common cancer among women in developed countries. Generally, 70% of primary breast cancer patients express estrogen receptor, thus endocrine therapy is often efficient for the disease using antiestrogen such as tamoxifen as well as aromatase inhibitor. During long-term therapy, however, a substantial proportion of women recurrent and acquire resistance to endocrine therapy. Understanding of the mechanism underlying acquired endocrine resistance would be a first step toward overcoming hormone-refractory cancer. In this study, we identified candidate genes that contributed to tamoxifen resistance in MCF-7 breast cancer cells by functional screening based on short hairpin RNA (shRNA) library. We found that several candidate genes were overexpressed in breast cancer patients and their abundance was positively associated with poor prognosis of cancer patients in clinical database. Moreover, the genes associated with poor prognosis also showed positive association with shorter survival for patients treated with tamoxifen. Expression levels of these candidate genes were upregulated in hydroxytamoxifen (OHT)-resistant MCF-7 cells (OHTR) compared with parental cells. Proliferation of OHTR cells was repressed by siRNAs targeting 26S subunits, non-ATPase 1 (PSMD1) and tetraspanin12 (TSPAN12). Furthermore, knockdown of PSMD1 inhibited cell cycle progression and p53 protein degradation. p21 and 14-3-3σ, target genes of p53, were upregulated by PSMD1 knockdown. These findings would be used for the development of alternative diagnostic and therapeutic options for endocrine-resistant breast cancers.
Citation Format: Toshiyuki Okumura, Kazuhiro Ikeda, Wataru Sato, Kuniko Horie-Inoue, Satoshi Inoue, Satoru Takeda, Koji Okamoto. Proteasome subunit PSMD1 participates in p53 degradation and regulates proliferation of breast cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3611. doi:10.1158/1538-7445.AM2017-3611</jats:p
Lecideoid lichens of Prince Olav Coast and Soya Coast, Enderby Land, East Antarctica
No full textFive species of lecideoid lichens belonging to three genera are reported as new to the flora of the Prince Olav Coast and the Soya Coast, Enderby Land, East Antarctica; they are Carbonea capsulata (DODGE & BAKER) HALE, Lecidea andersonii R. FILSON, Lecidea cancriformis DODGE & BAKER, Lecidea soyaensis M. INOUE and Lecidella siplei (DODGE & BAKER) M. INOUE. All are endemic to Antarctica. An examination was made of the collections from the region, which were collected mainly by the author under the project of the 27th Japanese Antarctic Research Expedition (JARE-27,during January 1986 and February 1987). The type and authentic specimens of possibly related species have been restudied. Lecidea soyaensis M. INOUE is new to science and Lecidella siplei (DODGE & BAKER) M. INOUE is proposed as a new combination. Taxonomic and chemical data as well as a key to the known taxa are provided
The Hobby of Electronic Circuit Engineering
No full textThis website (originally created in Japanese and translated into English using translation software) by a Japanese systems engineer, Seiichi Inoue, provides an extensive overview of electronic circuit engineering. Topics covered include: Basic knowledge of Electronic parts, Basic knowledge of Engineering Instruments, an Introduction of Engineering Method, and the Assembly Process. A variety of electronic circuits and their uses are provided, as well as a separate section on PIC electronic circuits. The language may be difficult to follow at times given the translation, but still a gem of a site for anyone wanting to build some circuits! Keep in mind that in some sections, the author notes that he is "describing while studying, there seems to be mistakes in the contents. Do at your own risk." For some further browsing, he includes sections on his other interests, such as 3D photography, java programming, CAD, Japanese customs and the Japanese language
Sonographic classification of testicular tumors by tissue harmonic imaging: experience of 58 cases
No full text金沢大学博士（保健学）博士論文要旨Abstract 以下に掲載：Journal of medical ultrasonics 45(1) pp.103-111 2017. Springer. 共著者：Atsuo Kawamoto, Tadashi Hatano, Kazuhiro Saito, Rie Inoue, Toshitaka Nagao, Shigeru Sanadathesi
The paracrine effect of adipose-derived stem cells inhibits osteoarthritis progression
No full text博士論文本文Full 以下に掲載：BMC musculoskeletal Disorders 16(236) pp.1-10 2015. Springer. 共著者：Kazunari Kuroda, Tamon Kabata, Katsuhiro Hayashi, Toru Maeda, Yoshitomo Kajino, Shintaro Iwai, Kenji Fujita, Kazuhiro Hasegawa, Daisuke Inoue, Naotoshi Sugimoto, Hiroyuki Tsuchiy
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