1,079 research outputs found
The Ernst Denis Monument in Lesser Town Square
No full textThe segment from the 1928 weekly Elektajournal Issue No. 3 shows events preceding the installation and subsequent unveiling of a monument to the French historian and Slavicist Ernest Denis in Lesser Town Square (Malostranské náměstí) in Prague. Members of the Society for the Construction of Denis´s Monument use a maquette to find the best place for the statue. The event is attended by the author of the monument, sculptor Karel Dvořák. A shot of the author Dvořák in his studio, located in the courtyard of a house on Janáček Embankment (Janáčkovo nábřeží) in Smíchov, Prague. Digging works for the pedestal followed by shots from a segment from the 1928 weekly Elektajournal Issue No. 45 featuring the unveiling of the memorial on 27 October 1928, the eve of the 10th anniversary of the Czechoslovak Republic. President Tomáš Garrigue Masaryk, Minister of Education Milan Hodža, Prague Mayor Karel Baxa, General Jan Syrový, member of Parliament Antonín Uhlíř, French General Eugene Mittelhauser, French politician Alfred Oberkirch, and others are present on the stage. A speech by Minister of Foreign Affairs Edvard Beneš. A shot of President T. G. Masaryk and Edvard Beneš
The aspartic proteinase family of three Phytophthora species
No full textBackground - Phytophthora species are oomycete plant pathogens with such major social and economic impact that genome sequences have been determined for Phytophthora infestans, P. sojae and P. ramorum. Pepsin-like aspartic proteinases (APs) are produced in a wide variety of species (from bacteria to humans) and contain conserved motifs and landmark residues. APs fulfil critical roles in infectious organisms and their host cells. Annotation of Phytophthora APs would provide invaluable information for studies into their roles in the physiology of Phytophthora species and interactions with their hosts. Results - Genomes of Phytophthora infestans, P. sojae and P. ramorum contain 11-12 genes encoding APs. Nine of the original gene models in the P. infestans database and several in P. sojae and P. ramorum (three and four, respectively) were erroneous. Gene models were corrected on the basis of EST data, consistent positioning of introns between orthologues and conservation of hallmark motifs. Phylogenetic analysis resolved the Phytophthora APs into 5 clades. Of the 12 sub-families, several contained an unconventional architecture, as they either lacked a signal peptide or a propart region. Remarkably, almost all APs are predicted to be membrane-bound. Conclusions - One of the twelve Phytophthora APs is an unprecedented fusion protein with a putative G-protein coupled receptor as the C-terminal partner. The others appear to be related to well-documented enzymes from other species, including a vacuolar enzyme that is encoded in every fungal genome sequenced to date. Unexpectedly, however, the oomycetes were found to have both active and probably-inactive forms of an AP similar to vertebrate BACE, the enzyme responsible for initiating the processing cascade that generates the Aß peptide central to Alzheimer's Disease. The oomycetes also encode enzymes similar to plasmepsin V, a membrane-bound AP that cleaves effector proteins of the malaria parasite Plasmodium falciparum during their translocation into the host red blood cell. Since the translocation of Phytophthora effector proteins is currently a topic of intense research activity, the identification in Phytophthora of potential functional homologues of plasmepsin V would appear worthy of investigation. Indeed, elucidation of the physiological roles of the APs identified here offers areas for future study. The significant revision of gene models and detailed annotation presented here should significantly facilitate experimental design
Anxiety narrative and the construction of distance in the film Claire Denis “Both Sides of the Blade”
No full textThe article is devoted to the film by Claire Denis “ Both Sides of the Blade “ (Avec amour et acharnement), the author analyzes
the techniques by which the narrative is built and distance is constructed. Using the tools of structural and post-structural analysis
(R. Barth, G. Deleuze), the concept of physicality, the author identifies the functions of close-up, speech, which form the space of the
intimate. The elements of genres that build intrigue in the film are analyzed. Intimate acts not so much as a form of communication,
but as a way of leveling the distance. The author analyzes the nature of the camera, its role in building the narrative and comes to
the conclusion that the structure of the film, by colliding speech and action, reveals their inconsistency and builds a kind of intrigue
between the author and the viewer
Global and local asymptotics for the busy period of an M/G/1 queue
No full textWe consider an M/G/1 queue with subexponential service times. We give a simple derivation of the global and local asymptotics for the busy period. Our analysis relies on the explicit formula for the joint distribution for the number of customers and the length of the busy period of an M/G/1 queue. © 2010 The Author(s).</p
Dieu caché. Dieu révélé un défi pour notre temps
No full textThe question of the hidden God has haunted Christian theology especially since Martin Luther expressed it so graphically. In this article, Luther's position is set alongside those of K. Barth, G. Ebeling, and E. Jiingel. The author then tackles the thought of W. Weischedel, whose philosophical theology opens up surprising avenues in the realm of the issue of the hidden God and of the idea of God in the modern world.La question du Dieu caché habite la théologie chrétienne surtout depuis que Martin Luther lui a donné une expression frappante. Dans cet article, la position de Luther est comparée avec celles de K. Barth, G. Ebeling et E. Jüngel. Dans un deuxième temps, l'auteur se confronte avec la pensée de W. Weischedel, dont la théologie philosophique ouvre des perspectives étonnantes en regard à la problématique du Dieu caché et de l'affirmation de Dieu dans le monde contemporain.Müller Denis. Dieu caché. Dieu révélé un défi pour notre temps. In: Revue d'histoire et de philosophie religieuses, 64e année n°4, Octobre-décembre 1984. pp. 345-364
Solar Analysis on Buildings of Favelas in São Paulo to Estimate PV Potential
No full textIn the Global South, large urban spaces resulted in the duality between the so-called ‘formal’ and ‘informal’ cities. It is the case of São Paulo, a twenty-two-million people metropolis and a financial hub in Latin America. Albeit a vast literature addresses the social-spatial segregation emerging from this dual built environment, the scarcity of spatial datasets regarding informal settlements also enforces a geo-information segregation, resulting in a terra incognita. This is exemplar in favelas, defined as precarious, spontaneous, and unorganised land occupation built on third-party property, most of which lack cadastral data. Since favelas are often not mapped, assessing urban phenomena becomes a technical challenge for several application domains, e.g., the energy one. A recent public initiative in Brazil estimates solar irradiation and photovoltaic potential for buildings at city scale, but favelas are intentionally excluded from the resulting web-based solar maps. Technicians believe that the absence of a spatial pattern in favelas calls for investigation on how to refine a roof mapping methodology. The main research question becomes: “How far is it possible to perform solar analysis on buildings of favelas in São Paulo, with the goal of estimating PV Potential?”. The research is structured into two topics: 1) Roof Mapping, which investigates the data pipeline that leads to a digital reconstruction of favelas; 2) Solar Irradiation, which investigates how existing solar irradiation modules – GRASS GIS, ArcGIS, CitySim, SimStadt, Ladybug and the one developed by Virtual City Systems – perform when assessing buildings of favelas. From a roof mapping perspective, the experiments reveal that the absence of cadastral datasets represents a complex technical challenge. Nevertheless, the reconstructed and post-processed building footprints cover the extension of the cadastral footprints that are available for the study area, with building shapes that are satisfactory as a first approximation. Regarding the solar irradiation perspective, qualitative and quantitative analyses are carried out to compare the results coming from the six solar modules. The qualitative analysis indicates that each solar module offers potentialities but also limitations. Therefore, a straightforward choice is not possible, since the optimal solution will be derived from a data-driven approach that considers, among other factors: the scale of the favela, its topographical characteristics, the presence/absence of urban features other than buildings (such as vegetation), a possible pre-selection of buildings of interest, etc.; The quantitative analysis reveals that ArcGIS outputs an annual summation of irradiation values that is the closest to the one offered by the meteorological station of São Paulo, adopted as ground truth. Nevertheless, from an accuracy perspective, CitySim outputs a daily curve that best corresponds to the ground truth one. In conclusion, based on the geometrical model and the weather dataset criteria, the author expresses his preference for a raster-based solar module – GRASS GIS or ArcGIS – if, on the one hand, the reconstructed building footprints result in an unrealistic or excessively complex vector-based model. On the other hand, if the resulting vector-based model is simple enough and representative of the built environment of the favela, the author suggests the adoption of CitySim.Geomatic
sj-docx-2-tab-10.1177_1759720X211057975 – Supplemental material for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)
No full textSupplemental material, sj-docx-2-tab-10.1177_1759720X211057975 for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) by Denis Poddubnyy, Xenofon Baraliakos, Filip Van den Bosch, Jürgen Braun, Laura C. Coates, Vinod Chandran, Torsten Diekhoff, Floris A. van Gaalen, Lianne S. Gensler, Niti Goel, Alice B. Gottlieb, Désirée van der Heijde, Philip S. Helliwell, Kay Geert A. Hermann, Deepak Jadon, Robert G. Lambert, Walter P. Maksymowych, Philip Mease, Peter Nash, Fabian Proft, Mikhail Protopopov, Joachim Sieper, Murat Torgutalp and Dafna D. Gladman in Therapeutic Advances in Musculoskeletal Disease</p
sj-docx-1-tab-10.1177_1759720X211057975 – Supplemental material for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)
No full textSupplemental material, sj-docx-1-tab-10.1177_1759720X211057975 for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) by Denis Poddubnyy, Xenofon Baraliakos, Filip Van den Bosch, Jürgen Braun, Laura C. Coates, Vinod Chandran, Torsten Diekhoff, Floris A. van Gaalen, Lianne S. Gensler, Niti Goel, Alice B. Gottlieb, Désirée van der Heijde, Philip S. Helliwell, Kay Geert A. Hermann, Deepak Jadon, Robert G. Lambert, Walter P. Maksymowych, Philip Mease, Peter Nash, Fabian Proft, Mikhail Protopopov, Joachim Sieper, Murat Torgutalp and Dafna D. Gladman in Therapeutic Advances in Musculoskeletal Disease</p
sj-7z-3-tab-10.1177_1759720X211057975 – Supplemental material for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)
No full textSupplemental material, sj-7z-3-tab-10.1177_1759720X211057975 for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) by Denis Poddubnyy, Xenofon Baraliakos, Filip Van den Bosch, Jürgen Braun, Laura C. Coates, Vinod Chandran, Torsten Diekhoff, Floris A. van Gaalen, Lianne S. Gensler, Niti Goel, Alice B. Gottlieb, Désirée van der Heijde, Philip S. Helliwell, Kay Geert A. Hermann, Deepak Jadon, Robert G. Lambert, Walter P. Maksymowych, Philip Mease, Peter Nash, Fabian Proft, Mikhail Protopopov, Joachim Sieper, Murat Torgutalp and Dafna D. Gladman in Therapeutic Advances in Musculoskeletal Disease</p
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