186,482 research outputs found
Recherchebreen delta formation and glacier flow velocity data
No full text<p>Data supporting our study on the rapid delta formation connected to glacier surge. The dataset contains positions of delta shoreline and centreline length (2020-2022) together with glacier flow velocity derived from Sentinel-1. Delta-related data produced by Jan Kavan, glacier velocity data by Adrian Luckman.</p>
Studium NK receptorů a jiných proteinů metodami rekombinantní exprese a hmotnostní spektrometrie
No full textUniverzita Karlova v Praze P írodov decká fakultař ě Katedra biochemie Studium receptor NK bun k a jinýchů ě protein pomocí rekombinantní expreseů a hmotnostní spektrometrie Autoreferát dizertační práce Daniel Kavan Školitel: Prof. RNDr. Karel Bezouška, DSc. Praha 2010 Daniel Kavan Úvod Úvod NK bu ky a jeden z jejich receptor CD69ň ů P irození zabiječi (NK bu ky) jsou subpopulacíř ň velkých granulárních lymfocyt , kterým na bun čnémů ě povrchu schází receptory charakteristické pro B a T bu ky.ň Jsou nicmén charakterizovány p ítomností NKp46 a NKp30ě ř [Moretta L. et. al. 2002]. Pojmenování bun k p irozeníě ř zabiječi vzniklo podle funkce v organismu, protože nepot ebují žádnou p edchozí aktivaci a p esto jsou schopnyř ř ř eliminovat nenormální (tedy infikované nebo transformované) bu ky z tkánň ě [Kiessling R. et. al. 1975]. Tato funkčnost je založena na kontrole MHC molekul I. T ídyř okolních bun k. Výsledná akce (zničení nebo nezničeníě cílové bu ky) je výsledkem rovnováhy aktivačních aň inhibičních signál zprost edkovanými povrchovýmiů ř receptory a p evedenými na konkrétní signální dráhyř [Raulet D. H. et. al. 2001]. Specifita NK bun k není závislá na jediném druhuě receptoru, jako je tomu u B a T bun k, ale je dánaě r znorodostí jejich povrchových receptor [Lanier L. L.ů ů 2005]. Tyto receptory pak...Charles University in Prague Faculty of Science Department of Biochemistry Studies of NK cell receptors and other proteins using recombinant expressions and mass spectrometry Summary of Ph. D. Thesis Daniel Kavan Supervisor: Prof. RNDr. Karel Bezouška, DSc. Prague 2010 Daniel Kavan Introduction Introduction NK cells and CD69 as one of their surface receptors Natural killer cells (NK cells) are the subpopulation of large granular lymfocytes, which lacks the surface receptors typical for B cells or T cells. They are characterized by the presence of NKp46 and NKp30 [Moretta L. et. al. 2002], however. They were named natural killers according to their function in the organism, as they do not need any activation and nevertheless they are able to eliminate abnormal (i. e. infected or transformed) cells from the tissue [Kiessling R. et. al. 1975]. This function is dependent on scanning the major histocompatibility complex (MHC) class I molecules of ambient cells. The resulting action (killing or not killing the target cell) is dependent on the balance of activating and inhibiting signals mediated by the NK cell surface receptors and forwarded to the specific signaling pathway [Raulet D. H. et. al. 2001]. Specificity of NK cells is not based only on one type of antigen receptor as it is in case of T and B cells,...Department of BiochemistryKatedra biochemieFaculty of SciencePřírodovědecká fakult
sj-zip-1-pih-10.1177_09544119221123431 – Supplemental material for An AI based digital-twin for prioritising pneumonia patient treatment
No full textSupplemental material, sj-zip-1-pih-10.1177_09544119221123431 for An AI based digital-twin for prioritising pneumonia patient treatment by Neeraj Kavan Chakshu and Perumal Nithiarasu in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine</p
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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