146 research outputs found
Bellis medio, Bellis minore, Bellis maggiore, Clematide seconda, Vinca per vinca
No full text1-2. Nome scientifico: Bellis perennis L.
(Asteraceae, Compositae)
Nome attuale: Pratolina
3. Nome scientifico: Leucanthemum vulgare Lam.
(Asteraceae, Compositae)
Nome attuale: Margherita
4-5. Nome scientifico: Vinca minor L.
(Apocinaceae)
Nome attuale: Pervinc
Opposite influence of light and blindness on pituitary-gonadal function
No full textSome environmental factors may influence the pituitary-gonadal function. Among these, light plays an important role in animal and in humans. The effect of light on the endocrine system is mediated by the pineal gland, through the modulation of melatonin secretion. In fact, melatonin secretion is stimulated by darkness and suppressed by light, thus its circadian rhythm peaks at night. Light plays a favourable action on the hypothalamic-pituitary axis likely inhibiting melatonin secretion, even if the exogenous melatonin administration does not seem to impair the hormonal secretions of this axis. The basal and rhythmic pituitary-gonadal hormone secretions is regulated by a central clock gene and some independent clock genes present in the peripheral tissues. Light is able to induce the expression of some of these genes, thus playing an important role in regulating the hormonal secretions of pituitary -gonadal axis and the sexual and reproductive function in animals and humans. The lack of light stimulus in blind subjects induces increased plasma melatonin concentrations with a free-running rhythm of secretion, which impairs the hormonal secretions of pituitary-gonadal axis, causing disorders of reproductive processes in both sexes. <br/
Theodore Roosevelt by Berton Bellis [St. Louis? 1919].
No full textVerse.; Roosevelt, Theodore.; On verso, Copies 1-10: {stamp} Gift Author MAR 10 1919
The early development of the cult of St Katherine of Alexandria with particular reference to England
No full textPhDSt Katherine of Alexandria, traditionally martyred c. 305, became one of the most
popular saints of the later Middle Ages. Whilst most modem studies concentrate on
the period of the cult's greatest popularity in the fourteenth and fifteenth centuries,
this thesis examines the early formative period down to c. 1200. In so doing it seeks
to clarify, as far as possible, the early history of the cult and to identify the means by
which it was transmitted from east to west. The paucity of surviving source material
hasn ecessitateda cross-disciplinarya pproacht o follow the cult's transmissionf rom
its Byzantine homeland into Western Europe. A major theme in this study is the role
played by relics in the development of Katherine's cult. Initially, no relics of the
saint existed and her eastern cult grew through Katherine's inclusion in liturgical and
hagiographicalw orks. In this early period artistic representationsp rovided
Katherine's only physical presence. Similarly the cult initially grew in Western
Europev ia hagiographiesa nd artistic representationsh, owever, it was not until the
emergenceo f primary relics of Katherine in late tenth-centuryS inai and
subsequentlyin eleventh-centuryN ormandy that her cult really begant o developi n
the west.
Chapter one surveys existing research on the development of Katherine's Passio.
Chaptert wo discussese videncef or the historical Katherine, whilst chaptert hree
investigates the origins of her cult in the Byzantine Empire and its transmission to
Italy. Chapter four is a regional study examining the introduction of Katherine's cult
into Normandy, following the acquisition of primary relics by Holy Trinity
monastery, Rouen, c. 1030. The relationship between the foundation of Holy Trinity,
its acquisition of Katherine's relics and the development of her cult is placed in the
social and political context of eleventh-centuryN ormandy. Clerical and lay attitudes
to Katherine's cult are investigated using an eleventh-century collection of miracles
performed by her Norman relics, translated here into English for the first time.
Chapter five considers the development of Katherine's English cult down to c. 1200.
This was closer to the Byzantine model rather than the Norman and took place
through her inclusion in liturgical and hagiographical works and through the interest
of certain identifiable individuals
Abraham Lincoln By Berton Bellis. [A poem of 4 stanzas] [1919].
No full textLincoln, Abraham.; Verse.; On verso, Copy 1-6: {stamp} Gift Author FEB 1, 1919; On recto, Copy 3: [1919]
ASO Author Reflections: Hepatopancreatoduodenectomy: Why, When, and How?
No full textHepatopancreatoduodenectomy: Why, When, and How
Use of serum pituitary antibodies to improve the diagnosis of hypophysitis
No full text: Lymphocytic hypophysitis is characterized by an extensive infiltration of lymphocytic cells. Pituitary biopsy is the gold diagnostic standard for lymphocytic hypophysitis but the disease occurs with moderate or without pituitary enlargement. The role of antipituitary antibodies (APA) in autoimmune hypophysitis is still discussed due to various methodological difficulties. Indirect immunofluorescence, a widely employed method to detect APA at this time produces highly variable results due to the use of human or animal pituitary substrates. For many years the authors have conducted a re-evaluation of APA by immunofluorescence in patients with other autoimmune diseases and in patients with apparently idiopathic hypopituitarism, using pituitary from young baboons as substrate but considering a predetermined cut-off of the titer and immunofluorescence pattern. This procedure allowed us to find out those with autoimmune pituitary impairment and to foresee the kind of future hypopituitarism in those with pituitary function still normal. Moreover, in APA positive patients, the use of a second step of a double immunofluorescence method allowed identification of the pituitary cells targeted by APA, verifying the correspondence with the kind of hypopituitarism, also when present in subclinical stage. However, to carry out an international workshop comparing the detection of APA by immunofluorescence using different substrates could contribute to verify the best choice to improve the sensitivity and specificity of this method
Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects
No full textPurpose: This publication reviews the accepted knowledges and the findings still discussed on several features of autoimmune hypophysitis, including the most recently described forms, such as IgG4 and cancer immunotherapy- related hypophysitis. Methods: The most characteristic findings and the pending controversies were derived from a literature review and previous personal experiences. A single paragraph focused on some atypical examples of the disease presenting under confounding pretences. Results: Headache, visual field alterations and impaired pituitary secretion are the most frequent clinical findings of the disease. Pituitary biopsy, still considered the gold diagnostic standard, does not always receive consent from the patients. The role of magnetic resonance imaging is limited, as this disease may generate images similar to those of other diseases. The role of antipituitary and antihypothalamus antibodies is still discussed owing to methodological difficulties and also because the findings on the true pituitary antigen(s) are still debated. However, the low sensitivity and specificity of immunofluorescence, one of the more widely employed methods to detect these antibodies, may be improved, considering a predetermined cut-off titre and a particular kind of immunostaining. Conclusion: Autoimmune hypophysitis is a multifaceted disease, which may certainly be diagnosed by pituitary biopsy. However, the possible different clinical, laboratory and imaging features must be considered by the physician to avoid a misdiagnosis when examining a possibly affected patient. Therapeutic choice has to be made taking into account the clinical conditions and the degree of hypothalamic-pituitary involvement, but also considering that spontaneous remissions can occur
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