4,103 research outputs found
Planning and Visualization for Automated Robotic Crane Erection Processes in Construction
No full textEffects of amorphous silicon capping layer on arsenic redistribution during TiSi2 formation
No full textDuring titanium silicide(TiSi2) formation by rapid thermal annealing(RTA), the redistribution of implanted arsenic was investigated by means of Auger electron spectroscopy(AES) and secondary-ion mass sepectroscopy(SIMS). By using 30nm amorphous silicon(a-Si) film deposited sequentially on 50nm titanium film without breaking the vacuum, the As dopant redistribution is suppressed due to the reduction of consumption of silicon substrate(Si-sub) during TiSi2 formation. The AES shows that the silicon, which is required for TiSi2 formation, is supplied from the a-Si film more rapidly than from the Si-sub. Also, the conversion of deposited Ti film into TiSi2 is complete because the a-Si film on Ti film prevents the infiltration of oxygen impurity into the Ti film during the exposure to air before annealin
INTEGRATED ECOLOGICAL PLANNING IN SINGAPORE: NEOTIEWPIA ECO-VILLAGE IN BUSTLING METROPOLITAN
Full text linkABSTRACT :The Neotiewpia Eco-Village is located within the Lim Chu Kang district at the north of Singapore. The Eco-Village only comprised of 3.5 sq km. Meanwhile the area was
dominated by farms, chalets and Sungei Buloh Wetland Reserve. In 2006, National University of Singapore, School of Design and Environment (SDE), MSc. Environmental Management and Nature Society of Singapore initiated an ecological planning exercise within the Neotiewpia site
to reduce the environmental impact from the development while providing Eco-friendly Tourism and R&D activities that feasible in the site. We did participate in the exercise and we tried explaining the ecological process, the limitation and potential development for integrated
ecological planning framework in Developing Countries like Indonesia, Brazil, etc with high ecological-values ecosystems. The Vision of Neotiewpia was “A Model Eco-Village that Respects its Natural Heritage, Builds Strong Community Links and Promotes Economic Development on Nature’s Premises." And Neotiewpia was successfully planned and designed with integrated ecological planning approach. It embraced the land evaluation and impact assessment. Further the plan was found feasible by the Singapore Government by earmarking the Lim Chu Kang and Kranji for Agri-tainment development in 2008 (although partially
implemented). The Neotiewpia or Lim Chu Kang area was found thriving with Green-Economy and Agro-Tourism. This integrated ecological planning could be translated to other areas in Developing Countries with agriculture potential and facing development pressures such as Neotiewpia. This concept would give alternate Green-Solution to the current economic crisis
Natural Variation of the Circadian Clock in Neurospora
No full textMost living organisms on earth experience daily and expected changes from the rotation of the earth. For an organism, the ability to predict and prepare for incoming stresses or resources is a very important skill for survival. This cellular process of measuring daily time of the day is collectively called the circadian clock. Because of its fundamental role in survival in nature, there is a great interest in studying the natural variation of the circadian clock. However, characterizing the genetic and molecular mechanisms underlying natural variation of circadian clocks remains a challenging task. In this chapter, we will summarize the progress in studying natural variation of the circadian clock in the successful eukaryotic model Neurospora, which led to discovering many design principles of the molecular mechanisms of the eukaryotic circadian clock. Despite the success of the system in revealing the molecular mechanisms of the circadian clock, Neurospora has not been utilized to extensively study natural variation. We will review the challenges that hindered the natural variation studies in Neurospora, and how they were overcome. We will also review the advantages of Neurospora for natural variation studies. Since Neurospora is the model fungal species for circadian study, it represents over 5 million species of fungi on earth. These fungi play important roles in ecosystems on earth, and as such Neurospora could serve as an important model for understanding the ecological role of natural variation in fungal circadian clocks.Advances in Genetics, Vol. 99
Corrigendum to “A generic multi-level framework for microscopic traffic simulation with automated vehicles in mixed traffic” [Transport. Res. Part C: Emerg. Technol. 110 (2020) 291–311] (Transportation Research Part C (2020) 110 (291–311), (S0968090X19304322), (10.1016/j.trc.2019.11.019))
No full textThe authors regret that a contributing author was missing from the list of authors. The complete list of authors should be: “S.C. Calvert, B. van Arem, & J. W. C. van Lint”. All are with Delft University of Technology, Department of Transport & Planning, The Netherlands updated as above. The authors would like to apologise for any inconvenience caused.Transport and Plannin
Towards the Holy Grail: combining system dynamics and discrete-event simulation in healthcare
No full textThe idea of combining discrete-event simulation and system dynamics has been a topic of debate in theoperations research community for over a decade. Many authors have considered the potential benefits ofsuch an approach from a methodological or practical standpoint. However, despite numerous examples ofmodels with both discrete and continuous parameters in the computer science and engineering literature,nobody in the OR field has yet succeeded in developing a genuinely hybrid approach which truly integratesthe philosophical approach and technical merits of both DES and SD in a single model. In this paperwe consider some of the reasons for this and describe two practical healthcare examples of combinedDES/SD models, which nevertheless fall short of the “holy grail” which has been so widely discussed inthe literature over the past decade
Elevated levels of placental growth factor represent an adaptive host response in sepsis
Full text linkRecently, we demonstrated that circulating levels of vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) are increased in sepsis (Yano, K., P.C. Liaw, J.M. Mullington, S.C. Shih, H. Okada, N. Bodyak, P.M. Kang, L. Toltl, B. Belikoff, J. Buras, et al. 2006. J. Exp. Med. 203:1447-1458). Moreover, enhanced VEGF/Flk-1 signaling was shown to contribute to sepsis morbidity and mortality. We tested the hypothesis that PlGF also contributes to sepsis outcome. In mouse models of endotoxemia and cecal ligation puncture, the genetic absence of PlGF or the systemic administration of neutralizing anti-PlGF antibodies resulted in higher mortality compared with wild-type or immunoglobulin G-injected controls, respectively. The increased mortality associated with genetic deficiency of PlGF was reversed by adenovirus (Ad)-mediated overexpression of PlGF. In the endotoxemia model, PlGF deficiency was associated with elevated circulating levels of VEGF, induction of VEGF expression in the liver, impaired cardiac function, and organ-specific accentuation of barrier dysfunction and inflammation. Mortality of endotoxemic PlGF-deficient mice was increased by Ad-mediated overexpression of VEGF and was blocked by expression of soluble Flt-1. Collectively, these data suggest that up-regulation of PlGF in sepsis is an adaptive host response that exerts its benefit, at least in part, by attenuating VEGF signaling
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