51,309 research outputs found
Middle meningeal artery embolization as standalone treatment versus combined with surgical evacuation for chronic subdural hematomas: systematic review and meta-analysis
OBJECTIVE Middle meningeal artery embolization (MMAE) is a novel treatment for chronic subdural hematomas (cSDHs) with high variability of use across practitioners and institutions. This study sought to investigate whether standalone MMAE may be an effective alternative to combined MMAE and surgery for select patients with cSDH. METHODS The authors searched the Medline and Embase databases for studies reporting outcomes specific to standalone MMAE and combined MMAE and surgery. The Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) tool was used to assess risk of bias in each included study. Patient characteristics were compared between cohorts, and rates of surgical recurrence of standalone MMAE and combined MMAE and surgery were pooled using random-effects models. RESULTS Four hundred two unique patients (156 with standalone MMAE and 246 with combined MMAE and surgery) were identified across 8 studies. Overall, the subdural thickness for the standalone MMAE group was modestly but statistically significantly smaller (16.8 vs 18.8 mm, estimated p value 0.002), and the mean follow-up time was significantly longer for the standalone MMAE group (5.4 vs 2.3 months, estimated p value < 0.001); there were no significant differences between age, sex, and anticoagulant use. The surgical recurrence rates were not significantly different between the two groups (estimated p value 0.63). Using random-effects models, the surgical recurrence rates were estimated at 6.8% (95% CI 3.5%–11.2%) and 4.6% (95% CI 2.3%–7.7%) for standalone MMAE and combined MMAE and surgery, respectively. CONCLUSIONS Standalone MMAE for cSDH may yield a low rate of surgical recurrence, which may be comparable to that of combined MMAE and surgery. However, studies in this systematic review and meta-analysis were primarily single-arm studies prone to treatment bias. Future studies are needed to further investigate whether standalone MMAE may be an effective alternative to combined MMAE and surgical treatment for cSDH in select patients
SDS-PAGE of HoxEFUYH and HoxU expression from TG1/pBS(Kan)Synhox and TG1/pBS(Kan)HoxU grown anaerobically in complex media and LB media
<p><b>Copyright information:</b></p><p>Taken from "Inhibition of hydrogen uptake in by expressing the hydrogenase from the cyanobacterium sp. PCC 6803"</p><p>http://www.biomedcentral.com/1472-6750/7/25</p><p>BMC Biotechnology 2007;7():25-25.</p><p>Published online 23 May 2007</p><p>PMCID:PMC1904212.</p><p></p> Arrow indicates the expression of HoxU. pBS(Kan) is TG1/pBS(Kan) (negative control), and Synhox is TG1/pBS(Kan)Synhox
Vectors pBS(Kan)Synhox (A), pBS(Kan)HoxU (B), pBS(Kan)HoxEFU (C), pBS(Kan)HoxFU (D), pBS(Kan)HoxFUY (D), and pBS(Kan)HoxUYH (E)
<p><b>Copyright information:</b></p><p>Taken from "Inhibition of hydrogen uptake in by expressing the hydrogenase from the cyanobacterium sp. PCC 6803"</p><p>http://www.biomedcentral.com/1472-6750/7/25</p><p>BMC Biotechnology 2007;7():25-25.</p><p>Published online 23 May 2007</p><p>PMCID:PMC1904212.</p><p></p> Kanis the kanamycin resistance gene. The five genes coding for the hydrogenaseare
Time course of hydrogen productivity (via gas chromatography) incomplex medium for TG1/pBS(Kan), TG1/pBS(Kan)Synhox, BW25113 /pBS(Kan), and BW25113 /pBS(Kan)Synhox
<p><b>Copyright information:</b></p><p>Taken from "Inhibition of hydrogen uptake in by expressing the hydrogenase from the cyanobacterium sp. PCC 6803"</p><p>http://www.biomedcentral.com/1472-6750/7/25</p><p>BMC Biotechnology 2007;7():25-25.</p><p>Published online 23 May 2007</p><p>PMCID:PMC1904212.</p><p></p
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Wave turbulence of a rotating array of quantized vortices in the T → 0 temperature limit
The dynamics of quantized vortices in the zero temperature limit is currently of great interest, particularly in the case of the Fermi superfluid He-B. Here we study wave turbulence, generated by the librating motion of a rotating cylindrical container filled with He-B, in the limit of vanishing viscous forces at temperatures . The polarization of the quantized vortices with respect to the axis of rotation is measured using non-invasive NMR techniques. We observe a decrease of the polarization when the librating motion is started, and a two-stage relaxation process when the modulation of the rotation velocity is stopped. The first relaxation process is associated with the dissipation of large-scale flow stored in inertial waves and the solid body rotation of the vortex array. From the decay of these energy reservoirs we determine the rate of energy dissipation of large-scale flow. The later second process is related to the relaxation of Kelvin waves on individual vortices. This process is monitored by the recovery of the polarization. The existence of a Kelvin wave cascade at the lowest temperatures is currently a central open question. We supply some evidence for the cascade
The investıgatıon of effects on some of quality characterıstics of different drying medhods of cultivated species of oregano and thyme
Bu araştırma 2016-2017 yılında Konya ekolojik şartlarında kültürü yapılan bazı kekik türlerinin (O. vulgare, O. majorana, O. onites ve T. vulgaris), farklı kurutma işlemlerinin bazı kalite özellikleri üzerine etkilerini tespit etmek amacıyla yapılmıştır. Araştırmada tarla denemeleri Selçuk Üniversitesi Tıbbi Bitkiler Araştırma ve Uygulama Çiftliğinde; kalite analizler ise Ziraat Fakültesi Tıbbi Bitkiler Araştırma Laboratuvarında yürütülmüştür. Bu araştırmadan elde edilen sonuçlara göre; Farklı kekik türlerinin bazı kalite özellikleri üzerine uygulanan kurutma yöntemlerinin önemli etkilerinin olduğu söylenebilir. En yüksek uçucu yağ verimi gölgede kurutulmuş Ak kekik (O. majorana) herbasından (% 5.01) elde edilmiştir. Bununla birlikte uçucu yağ bileşenleri bakımından kekik türlerinde en yüksek karvakrol miktarı gölgede kurutulmuş İstanbul kekiğinden (O. vulgare) elde edilmiştir. Önemli uçucu yağ birleşenlerinden timol miktarı ise kurutma dolabında kurutulmuş Yayla kekiğinden (T. vulgaris) % 68.03 elde edilmiştir. Kekik türleri mineral içerikleri (Fe, Zn, Mn, N, P ve K) bakımından değerlendirildiğinde genel olarak üzerinde çalışılan türler arasında Bilyeli kekiğinin (O. onites) zengin olduğu söylenebilir. Bu çalışma kapsamında kekik türlerinin uçucu yağlarının antioksidan aktiviteleri bakımından İstanbul kekiğinin (O. vulgare) en yüksek kapasiteye sahip olduğu söylenebilir. Bu araştırma sonuçlarına göre; Konya ve benzer ekolojilerde kültürü yapılan kekik türlerinin hasat sonrası kurutma işlemlerinin kekik ürünleri kalitesi üzerine önemli etkilerinin olduğu belirlenmiştir.This research was carried out to determine the effects of some thyme and oregano species (O. vulgare, O. majorana, O. onites and T. vulgaris) cultivated under Konya ecological conditions in 2012-2013 on some quality properties of different drying methods. In the study, plant cultivated studies were carried out in The Research and Application arm Selcuk University, and analysed in The Medical Plants Research laboratory of Agricultural Faculty. According to the results obtained from this research; It can be said that drying methods applied on some quality properties of different thyme and oregano species have significant effects. The highest volaite oil yield was obtained from shade dried Akkekik (O. majorana) herbs (5.01%) . However, the highest amount of carvacrol in oregano species in terms of essential oil components was obtained from shade dried İstanbul oregano (O. vulgare). The amount of thymol, which is one of the importatnt essential oil components, was 68.3% from dried hightland thyme (T. vulgaris) in the drying cabinet. When thyme and oregano species are evaluated in terms of their mineral contest (Fe, Zn, Mn, N, P ve K) it can be said that Bilyeli oregano (O. onites ) is rich among the studied species in general. .In this study, it can be said that Istanbul oregano (O. vulgare) has the highest capacity in terms of antioxidant activities of essential oils of thyme or oregano species. According to the results of; post- harvest drying of thyme and oregano species cultivated in Konya and similar ecologies have significant effects on the quality of thyme or oregano products
E-book : Industrial Transformation In The Developing World (author: Michael T. Rock & David P. Angel)
Arsip Kuliah Online 2010: E-book : Industrial Transformation In The Developing World (author: Michael T. Rock & David P. Angel
Letter from Carl Hayden to P. J Moran
Letter from Carl T. Hayden to P. J. Moran concerning the alignment of the road to Bright Angel Trail
E-book : "industrial Transformations In The Developing World (author: Michael T. Rock & David. P Angel)
Arsip Kuliah Online 2010: E-book : "industrial Transformations In The Developing World (author: Michael T. Rock & David. P Angel
- …
