1,720,958 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Ultrastructure expansion microscopy in Trypanosoma brucei.
Get PDFThe recently developed ultrastructure expansion microscopy (U-ExM) technique allows us to increase the spatial resolution within a cell or tissue for microscopic imaging through the physical expansion of the sample. In this study, we validate the use of U-ExM in Trypanosoma brucei measuring the expansion factors of several different compartments/organelles and thus verify the isotropic expansion of the cell. We furthermore demonstrate the use of this sample preparation protocol for future studies by visualizing the nucleus and kDNA, as well as proteins of the cytoskeleton, the basal body, the mitochondrion and the endoplasmic reticulum. Lastly, we discuss the challenges and opportunities of U-ExM
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Biophysical and Structural Studies of CNTNAP2
No full textAt synapses, cell adhesion molecules provide connection between the presynaptic and postsynaptic membranes through homophilic and heterophilic interactions promoting synapse development, function, and plasticity. The synaptic adhesion molecules contactin 2 (CNTN2), and contactin associated protein-like 2 (CNTNAP2) have an emerging role at synaptic interaction networks. CNTNAP2 is a member of the neurexin superfamily of synaptic cell adhesion molecules; it is localized at the juxtaparanodes of myelinated axons at the Nodes of Ranvier where it mediates interactions between neurons and ensheathing glial cells and recruits potassium channels to the juxtaparanodes. CNTNAP2 is also found at synapses. Association, linkage, gene expression and imaging data highlight the role of CNTNAP2 in several neurodevelopment and neuropsychiatric disorders, including developmental language impairment, Morvan’s syndrome, and limbic encephalitis. Cell biology and immunological studies strongly indicate that CNTNAP2 binds to CNTN2. CNTNAP2 and CNTN2 form a macromolecular complex spanning axo-glial and synaptic contacts to maintain neuron-neuron and axo-glial interactions. Currently, it is not known how CNTNAP2 and CNTN2 interact, nor whether CNTNAP2 binds additional cell surface molecules. High-resolution information on the three dimensional atomic structure of CNTNAP2 is also not known.
The goal during of this master’s thesis project was to purify the extracellular domain of CNTNAP2 and several of its fragments, assess whether the extracellular domains of CNTNAP2 and CNTN2 interact directly using solid phase binding assays and obtain crystals of CNTNAP2 fragments. We are the first who did in vitro studies for characterize CNTNAP2 and their partner CNTN2. We found that CNTNAP2 is an endogenous ligand for CNTN2 and associates with nanomolar affinity. The binding of the extracellular domains of CNTNAP2 and CNTN2 are promoted by the presence of Ca2+. These data provide new platform for structural-functional study for CNTNAP2/CNTN2 complex. In the future, we will continue this project to map critical interactions sites on these proteins
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