1,115 research outputs found

    Study of preparation and transformation furo[2,3-c]quinolines a pyrrolo[2,3-c]quinolines

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    Zahříváním furo[2,3-c]chinolin-2,4(3aH,5H)-dionů v cyklohexylbenzenu s katalytickým množstvím N,N-dimethylpyridin-4-aminu byly připraveny furo[3,4-c]chinolin-3,4(1H,5H)-diony. Dále byla reakcí 3-amino-3-fenylchinolin-2,4(1H,3H)-dionu s ethyl(trifenylfosforanyliden)-acetátem ve vařícím xylenu připravena směs látek, z níž byly izolovány další látky. V rámci práce byly také provedeny mikrobiologické testy toxicity daných látek.Furo[3,4-c]quinoline-3,4(1H,5H)-diones were prepared by heating furo[2,3-c]quinoline-2,4(3aH,5H)-diones with cyklohexilbenzene with catalytic amount of N,N-dimethylpyridine-4-amine.Furthermore the reaction of 3-amino-3-fenylchinolin-2,4(1H,3H)-dion with ethyl(triphenylphosphoranylidene) afforded complex mixture of compounds. The microbiological test of selected compounds were also performedÚstav inženýrství ochrany životního prostřed

    Analysis of care in patients at risk for arterial hypertension in pharmacy I.

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    Analysis of care in patiens at risk for arterial hypertension in pharmacy I. Author: Stanislav Gregor1 Tutor: Josef Malý1 Consultant: Stanislav Havlíček2 1 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové 2 Czech Chamber of Pharmacists, Prague Introduction: Arterial hypertension represents a serious health problem. Despite of the fact that great attention is paid to an early diagnosis and therapy of arterial hypertension, it remains compensated insufficiently in a number of patients. Objectives: The aim of the thesis was to analyse the possibilities of pharmaceutical care provided to patients who are at risk of arterial hypertension. Methodology: Blood pressure was measured from the beginning of October till December 2012 in a public pharmacy in Moravská Třebová. The blood pressure was measured by a pharmacist by means of a validated and calibrated tonometer. Other data were collected from a directed interview with the pharmacy client. The data were evaluated in Microsoft Excel 2007 and processed by means of the frequency analysis. A retrospective analysis of drug problems was further performed in patients who have been using pharmacotherapy or food supplements. Results: The data were obtained from 196 pharmacy clients (31 % of men and..

    Funeral of General Stanislav Čeček in Prague

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    The segment captures the funeral of the Zborov hero, General Stanislav Čeček, held in Prague on 5 June 1930. The coffin with the deceased is transported from the Pantheon of the National Museum to the National Liberation Monument in Žižkov. The funeral procession includes not only representatives of the Czechoslovak Legions but also Prime Minister František Udržal and Minister of Supplies Rudolf Bechyně. General Rudolf Medek delivers a speech over the the late hero´s coffin (silent)

    GLIFO System and Symbolic Resolution of Quantum Problems

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    This project introduces the GLIFO (0–9) symbolic system for resolving high-complexity quantum equations, including the multi-body Schrödinger equation. A non-numerical method that simulates state convergence using symbolic resonance. Author: Shvardak Stanislav.## License This project is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). © 2025 Shvardak Stanislav – [email protected] Link to license: https://creativecommons.org/licenses/by/4.0

    In memory of Stanislav Martinát (1976–2023)

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    On Sunday, August 13, 2023, Stanislav Martinát – a respected Czech geographer and member of the Editorial Board of Moravian Geographical Reports journal – died after a short serious illness at the age of 47. Despite his relatively young age, Stanislav Martinát was one of the most productive and the most cited Czech geographers. He is the author or coauthor of over 100 peer-reviewed articles, of which more than 70 were published in journals indexed in the Web of Science database. This article is a collection of personal memories from people from different workplaces from several countries who had the opportunity to work with Stanislav (Standa) and to share a part of their life stage with him

    GLIFO System and Symbolic Resolution of Quantum Problems

    No full text
    This project introduces the GLIFO (0–9) symbolic system for resolving high-complexity quantum equations, including the multi-body Schrödinger equation. A non-numerical method that simulates state convergence using symbolic resonance. Author: Shvardak Stanislav.## License This project is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). © 2025 Shvardak Stanislav – [email protected] Link to license: https://creativecommons.org/licenses/by/4.0

    Syntheses of Novel Compounds Based on 4-Hydroxyquinolin-2(1H)-ones Potentially Applicable for Properties Modification or Protection of Materials

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    Předložená disertační práce se zabývá syntézou a reaktivitou 4-hydroxychinolin-2(1H)-onů, chinolin-2,4(1H,3H)-dionů a sloučenin z těchto látek dostupných, především derivátů kyseliny anthranilové. V literární části je kromě reaktivity přiblížena také biologická aktivita, přírodní výskyt a otenciální využití těchto sloučenin k úpravě vlastností nebo k ochraně materiálů. V druhé části práce jsou komentovány výsledky výzkumné činnosti autora publikované v odborné literatuře.Presented dissertation thesis is focused on a synthesis and reactivity of 4-hydroxyquinolin-2(1H)-ones, quinoline-2,4(1H,3H)-diones and the substances available therefrom, especially anthranilic acid derivatives. In the literary part, biological activity, natural occurrence, and potential application of these compounds at modifying properties and/or protecting materials are discussed in addition to reactivity. The second part of the thesis deals with the results of the research activities of the author published in the literature.Ústav chemi

    Yuriy Izdryk and the Stanislav phenomenon : postmodernists or "postmodernized" avant-garde?

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    The writers of the Stanislav Phenomenon according to a lot of Ukrainian literary scholars are the most representative branch of the Ukrainian postmodernism. This text tries to answer the question that members of this group are really postmodernists or rather they create some kind of the modern avant-garde. The author presents a story of the beginning of the Ukrainian postmodernism and the idea of the "postmodernized modernism" invented by Włodzimierz Bolecki. Based especially on the three novels of Yuriy Izdryk, one of the representative of the Stanislav Phenomenon, author tries to prove that the Ukrainian postmodernism does not exist but really is the "postmodernized" avant-garde

    Study of Novel Possibilities of Synthetic Utilization of 3-Hydroxyquinoline-2,4(1H,3H)-diones.

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    Tato práce se zabývá reaktivitou a možným syntetickým využitím 3-hydroxychinolin-2,4(1H,3H)-dionů. V literární části přibližuje hlouběji dosud známé reakce těchto sloučenin. Poznatky získané z experimentů provedených autorkou zahrnují jednak oxidaci titulních sloučenin kyselinou pentahydrogenjodistou a hydrolýzu oxidačních produktů, kterými jsou N-(?-ketoacyl)anthranilové kyseliny, jednak možnost jejich využití k syntézám 1 fenylfuro[2,3-c]chinolin-2,4(3aH,5H)-dionů.This diploma thesis is dealing with the reactivity and possible synthetic utilisation of 3-hydroxyquinoline-2,4(1H,3H)-diones. The reactions of mentioned compounds, which have been known until now, are reviewed in the literature search section. The knowledge achieved in the experiments carried out by the author include oxidation of these com-pounds by paraperiodic acid to N-(?-ketoacyl)anthranilic acids and their hydrolysis as well as a possibility of their exploitation to the synthesis of 1 fenylfuro[2,3-c]quinoline-2,4(3aH,5H)-diones.Ústav chemieobhájen

    Chronology and origin of «the Alakul culture» in the Trans-Urals. Reflections on the Stanislav A. Grigoriev concept

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    The paper is devoted to criticism of the concept of Alakul culture origin and history proposed by Stanislav Grigoriev. The author casts doubt on Stanislav Grigoriev opinion about the dating Alakul sites in the Trans-Urals within two separate time periods and about a direct genetic link of Alakul population and inhabitants of Sintashta sites
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