1,945 research outputs found
The pseudo‐βI‐turn: A new structural motif with a cis peptide bond in cyclic hexapeptides
No full textSynthesis and conformational analysis of three cyclic hexapeptides cyclo(‐Gly1‐Pro2‐Phe3‐Val4‐Xra5‐Phe6), Xaa= Phe (I), D‐Phe (II) and D‐Pro (III), were carried out to examine the influence of proline on the formation of reverse turns and the dynamics of hydrophobic peptide regions. Assignment of all 1H and 13C resonances was achieved by homo‐ and heteronuclear 2D‐NMR techniques (TOCSY, ROESY, HMQC, HMQC‐TOCSY and HMBCS‐270). The conformational analysis is based on interproton distances derived from ROESY spectra and homo‐ and heteronuclear coupling constants (E.COSY, HETLOC and HMBCS‐270). For structural refinements restrained molecular dynamics (MD) simulations in vacuo and in DMSO were performed. Each peptide exhibits two conformations in DMSO solution due to cis‐trans isomerism about the Gly‐Pro peptide bond. Surprisingly the cis‐Gly‐Pro segment in the minor isomers is not involved in a βVI‐turn, but forms a turn structure with cis‐Gly‐Pro in the i and i+ 1 positions. Although no stabilizing hydrogen bond is found in this turn, the φ and ψ‐angles closely correspond to a βI‐turn [Pro2:φ(i+ 1) ‐60°, ψ(i+ 1) ‐30° Phe3: φ(i+ 2) ‐100°, ψ(i+ 2) ‐50°]. Hence we call this structural element a pseudo‐βI‐turn. As expected, in the dominating all‐trans isomers proline occupies the i+ 1 position of a standard βI‐turn. Therefore, cis‐trans isomerization of the Gly1‐Pro2 amide bond only induces a local conformational rearrangement, with minor structural changes in other parts of the molecule. However, the geometry of the other regions is affected by the chirality of the i+ 1 amino acid for both isomers (βI for Phe5, βII′ for D‐Phe5 or D‐Prp5). Copyright © 1994, Wiley Blackwell. All rights reserve
The association between failed quit attempts and increased levels of psychological distress in smokers in a large New Zealand cohort
No full textAbstract Background Although the association between smoking status and poorer mental health has been well documented, the association between quit status and psychological distress is less clear. The aim of the present study is to investigate the association of smoking status and quit status with psychological distress. Methods Data for this study is from a single year of the Survey of Families, Income and Employment (SoFIE) conducted in New Zealand (2004/05) (n = 18,525 respondents). Smoking status and quit status were treated as exposure variables, and psychological distress (Kessler-10) was treated as the outcome variable. Logistic regression analyses were performed to determine the association of smoking with psychological distress in the whole adult population and quit status with psychological distress in the ex- and current-smoking population. Results Current smokers had higher rates of high and very high psychological distress compared to never smokers (adjusted odds ratio (aOR) = 1.45; 95% CI: 1.24-1.69). Unsuccessful quitters had much higher levels of high to very high levels of psychological distress (16%) than any other group. Moreover, compared to long-term ex-smokers, unsuccessful quitters had a much higher odds of high to very high levels of psychological distress (aOR = 1.73; 95% CI: 1.36-2.21). Conclusion These findings suggest that the significant association between smoking and psychological distress might be partly explained by increased levels of psychological distress among current smokers who made a quit attempt in the last year. This issue needs further study as it has implications for optimising the design of quitting support.</p
EVALUATION ON CONSISTENCY BETWEEN HJ-1 CCD AND TM IMAGES IN MONITORING FRACTIONAL GREEN VEGETATION COVER
No full textThe fractional green vegetation cover (Fc) is an important climate model parameter. Remote sensing technique has become one of the most effective means to acquire vegetation dynamics information. The CCD cameras onboard HJ-1 satellites (Environment and Disaster monitoring and forecasting Satellite constellation) are advanced in revisit frequency and image coverage compared with Landsat TM. This study aims to assess the capability of HJ-1 CCD images in monitoring of Fc in terms of comparing with the widely used TM images. The quality of HJ-1 CCD is compared with the same temporal TM image in two aspects: the image statistical analysis and the image application analysis. After the comparison between the HJ-1 CCD image and TM image of the same area. The results show a high level of uniform between HJ-1 and TM images. Therefore, the conclusion may be drawn that the HJ-1 CCD image is feasible and suitable for Fc monitoring.Engineering, Electrical & ElectronicGeosciences, MultidisciplinaryRemote SensingEICPCI-S(ISTP)
Konsep Pendidikan Untuk Perempuan Perspektif Nyai Hj. Masriyah Amva
No full textOne figure of a well-known female cleric in Cirebon is Nyai Hj. Masriyah Amva. He is a female ulama figure who is different from the others, Nyai Hj. Masriyah Amva became the caretaker of Kebon Jambu Al-Islamy Islamic Boarding School in Babakan Village, Ciwaringin Cirebon, where she became the leader of more than 1,000 male and female santri. The author presents this paper in the form of a qualitative approach, with qualitative descriptive methods, collection techniques using interview and observation methods, which are then analyzed by interactive analysis techniques namely data reduction, data presentation and drawing conclusions. This study aims to illustrate the Concept of Education for Perpective Women Nyai Hj. Masriyah Amva at Kebon Jambu Al-Islamy Islamic Boarding School. According to him, education for women consists of material elements, immaterial elements and character elements. The material element is education that equips students with various sciences according to their respective levels, while the immaterial element is that women are able to present and involve the Creator in all their life processes, according to Nyai Hj. Masriyah Amva, that is, women must be educated in such a way as to form a woman who is persistent, independent, has a personality, is pious and tough with hard prayers, hard efforts and always has positive thoughts.Salah satu sosok ulama perempuan yang sangat dikenal di Cirebon adalah Nyai Hj. Masriyah Amva. Beliau adalah sosok ulama perempuan yang berbeda dengan lainnya, Nyai Hj. Masriyah Amva menjadi pengasuh Pondok Pesantren Kebon Jambu Al-Islamy di Desa Babakan, Ciwaringin Cirebon, beliau menjadi pemimpin lebih dari 1.000 santri laki-laki dan perempuan. Penulis menyajikan tulisan ini dalam bentuk pendekatan kualitatif, dengan metode deskriptif kualitatif, teknik pengumpulan menggunakan metode wawancara dan observasi, yang kemudian dianalisis dengan teknik analisis interaktif yaitu reduksi data, penyajian data dan penarikan kesimpulan. Penelitian ini bertujuan untuk menggambarkan Konsep Pendidikan untuk Perempuan Perpektif Nyai Hj. Masriyah Amva di Pondok Pesantren Kebon Jambu Al-Islamy. Menurutya pendidikan untuk perempuan adanya unsur material, unsur imaterial dan unsur karakter. Unsur material adalah pendidikan yang membekali santrinya dengan berbagai ilmu pengetahuan sesuai jenjangnya masing-masing, sedangkan unsur Imaterial adalah para perempuan mampu menghadirkan dan melibatkan Sang Pencipta dalam semua proses kehidupannya, unsur karakter menurut Nyai Hj. Masriyah Amva yaitu perempuan harus dididik sedemikian rupa hingga terbentuklah sosok perempuan yang gigih, mandiri, berkepribadian, bertaqwa dan tangguh dengan do`a keras, usaha keras dan selalu berfikiran positif
A Business Model Analysis On Hj Nina’s Rental Housing Using Business Model Canvas Approach
No full textTangerang City has great potential for the growth of residential property projects. This region called thriving city due to economic growth which Tangerang City quite significantly from National. Terms of geographical, Tangerang City have access to strategic Jakarta so many transportation infrastructure could trigger growth property in the area. With the existence of business opportunities related to housing in Tangerang City, Mrs Hj Nina take advantage of these business opportunities by building land owned by property for a rented houses. But in running her business, Mrs Hj Nina has the main obstacle is competition around rented houses. One of the ways that Mrs Hj Nina’s rented house can explore the existing potential is by analyzing the right business model. Based on the results of the research on the identification of business model elements that exist in the house of Mrs Hj Nina, the author proposes several improvement programs for Mrs Hj Nina, namely expanding the house rent, develop business rented by diversifying business, adding facilities, doing community service, the owner having face to face meetings with rented houses, and house renters are active in the activities of local residents. With proposal the program for the improvement is expected to makes a business Mrs Hj Nina can develop and survived in the field of the business
VALIDATION FOR THE ABSOLUTE RADIOMETRIC CALIBRATION OF THE HJ-1B CCD SENSORS OF CHINA
No full textOn September 6, 2008, the satellite HJ-1B was launched into a sun-synchronous, near-polar orbit. In order to determine temporal changes of the absolute radiometric calibration of the HJ-1B satellite in flight, a program was carried out at DunHuang calibration field, Gansu province of China, from August 19 to 30, 2009. In this work, reflectance -based calibration method was employed to simulate the absolute calibration coefficients of the HJ-1B CCD sensors. Then the cotton field, cement court, water pool and test site was selected to validate the calibration coefficient. The validation results indicated that there had a good agreement between the imaged-based reflectance and the ground measurement of the type of cement court and test site. On the other hand, there had a disagreement of the type of cotton field and water because of the effect of mixed pixel.Geosciences, MultidisciplinaryRemote SensingEICPCI-S(ISTP)
KERUGIAN YANG DIDERITA OLEH DOKTER AKIBAT PENGELOLAAN DANA BADAN PENYELENGGARA JAMINAN SOSIAL KESEHATAN DI RUMAH SAKIT UMUM DAERAH HJ. ANNA LASMANAH BANJARNEGARA
No full textResearch with the title Losses Suffered by Doctors due to the Management
of “Badan Penyelenggara Jaminan Sosial Kesehatan” in the Hj. Anna
Lasmanah Hospital Banjarnegara was used based on the statement of the Hj.
Anna Lasmanah Hospital’s Director in 2018, dr. Agung Budianto. Research that
have been done by the author in order to find out the truth of the data about the
loss that experienced by doctors using normative methods through interviews
between the author and Hj. Anna Lasmanah Hospital’s Director as well as
several representatives of doctors or dentists and this interview also involve the
Head of “BPJS Kesehatan” Banjarnegara field office. The result of this
research is the loss that experienced by the doctors is not material losses but
immaterial losses. This immaterial losses is the disappointment of the doctors
with “BPJS Kesehatan” who did the late payments which make the economic
needed of doctors not being able to get on time
MONITORING OF DEGRADING GRASSLAND BASED ON HJ-1A-HSI IMAGE
No full textGrassland is one of the most important parts of ecosystem on the earth. In China, one of the best grass lands is degrading because of draught or effects of human activity. It is important to monitor the growing condition of degrading grasslands. LAI is an important variable which can accurately represent the growing situation of grass. With DSD method, hyper-spectral images from HJ-1A satellite are used to inverse LAI accurately by restraining the effect of background. In this paper, multi spectral image was used to retrieve LAI with BRDF method for comparing. The maps of LAI and degradation level in study area were made. According to the results, the DSD method can retrieve LAI of grassland accurately and the HSI image of HJ-1A is a potential ideal data source for monitoring grassland.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345638900196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Engineering, Electrical & ElectronicGeosciences, MultidisciplinaryRemote SensingCPCI-S(ISTP)
Continuing cognitive impairment after isolated transient global amnesia
No full textKessler J, Markowitsch HJ, Rudolf J, Heiss WD. Continuing cognitive impairment after isolated transient global amnesia. INTERNATIONAL JOURNAL OF NEUROSCIENCE. 2001;106(3-4):159-168.Fourteen patients were investigated 3-4 days after end of their transient global amnesia (TGA) with a number of neuropsychological tests. Their performance was compared with that of a control group. marched For ape, education. and profession. II was found that in spits of the common definition of TGA. impairments in both verbal and nonverbal long term memory and verbal fluency persisted and were in fact impaired to such a degree that it seemed unlikely that full recovery would have occurred within the next few days. We propose a major role of stress in the etiology and the recovery process of TGA and consider it likely that stress hormones are of major influence both in the triggering of TGA and the subsequent continuation of cognitive impairments
Decision-making deficits of Korsakoff patients in a new gambling task with explicit rules: Associations with executive functions
No full textBrand M, Fujiwara E, Borsutzky S, Kalbe E, Kessler J, Markowitsch HJ. Decision-making deficits of Korsakoff patients in a new gambling task with explicit rules: Associations with executive functions. NEUROPSYCHOLOGY. 2005;19(3):267-277.Decision-making deficits reflected by risky decisions in gambling tasks have been associated with frontal lobe dysfunctions in various neurologic and psychiatric populations. The question remains whether decision-making impairments are related to executive functions. The authors developed a new gambling task, the Game of Dice Task, with explicit and stable rules for reinforcement and punishment, to investigate relations between executive functions and risk-taking behavior in an explicit decision-making situation. A sample of 35 alcoholic Korsakoff patients and 35 healthy controls was examined with the Game of Dice Task and a neuropsychological test battery. Results show that Korsakoff patients are strongly impaired in this explicit decision-making task and that these disturbances are correlated with specific executive functions
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