30,651 research outputs found
Cell volume regulatory ion channels in cell proliferation and cell death.
No full textAlterations of cell volume are key events during both cell proliferation and apoptotic cell death. Cell proliferation eventually requires an increase of cell volume, and apoptosis is typically paralleled by cell shrinkage. Alterations of cell volume require the participation of ion transport across the cell membrane, including appropriate activity of Cl(-) and K(+) channels. Cl- channels modify cytosolic Cl(-) activity and mediate osmolyte flux, and thus influence cell volume. Most Cl- channels allow exit of HCO(3)(-), leading to cytosolic acidification, which in turn inhibits cell proliferation and favors apoptosis. K+ exit through K+ channels decreases cytosolic K+ concentration, which may sensitize the cell for apoptotic cell death. K+ channel activity further maintains the cell membrane potential, a critical determinant of Call entry through Ca(2+) channels. Call may, in addition, enter through Ca(2+)-permeable cation channels, which, in some cells, are activated by hyperosmotic shock. Increases of cytosolic Ca2+ activity may trigger both mechanisms required for cell proliferation and mechanisms, leading to apoptosis. Thereby cell proliferation and apoptosis depend on magnitude and temporal organization of Ca(2+) entry, as well as activity of other signaling pathways. Accordingly, the same ion channels may participate in the stimulation of both cell proliferation and apoptosis. Specific ion channel blockers may thus abrogate both cellular mechanisms, depending on cell type and condition
Ein vigolotrischer Weltkucker. Die Prosa des Albert Vigoleis Thelen im Zusammenhang mit dem deutschsprachigen Pikaroroman Frankfurt/M.,Berlin,Bern,New York, Paris, Wien:Peter Lang. Europäischer Verlag der Wissenschaft ,1997 3-631-49881-0
No full textContains fulltext :
98749.pdf (Publisher’s version ) (Closed access)K.-J. Hermanik Ein vigolotrischer Weltkucker. Die Prosa des Albert Vigoleis Thelen im Zusammenhang mit dem deutschsprachigen Pikaroroman Frankfurt/M.,Berlin,Bern,New York, Paris, Wien:Peter Lang. Europäischer Verlag der Wissenschaft ,1997 3-631-49881-
Habenaria wolongensis , K. Y. Lang 1984
No full textHabenaria wolongensis K.Y. Lang (1984: 314). Type:— CHINA. Sichuan, Wolong, 2200 m, 24 August 1982, K. Y. Lang, L. Q. Li & Y. Fei 1528 [lectotype designated here: PE! (barcode 01147127), isolectotype: PE! (barcode 01147128)]. Notes:— While designating the type of Habenaria wolongensis, K.Y. Lang has mentioned ‘ K. Y. Lang, L. Q. Li & Y. Fei 1528 (Typus, PE)’ in the protologue; however during a search for the type materials at PE, we found two specimens with that label. Evidently, they were of the same gathering and thus both of them should be regarded as syntypes (Art. 9.6, Art. 40 Note 1). In such circumstances, for typification, we had to choose one of them and we choose the specimen bearing the barcode no. 01147127 as the lectotype, it is the same specimen that has been illustrated in the protologue.Published as part of Pandey, Tirtha Raj & Jin, Xiao-Hua, 2021, Taxonomic notes and typification of some Habenaria species in the Pan-Himalaya, pp. 107-108 in Phytotaxa 489 (1) on page 108, DOI: 10.11646/phytotaxa.489.1.10, http://zenodo.org/record/575318
On the impact of electrolyte temperature on contact glow discharge electrolysis
No full textThis study aims at disclosing the effect of small temperature drops (10-15 degrees C) of the electrolyte on Contact Glow Discharge Electrolysis (CGDE). In our experiments, we measure the temperature change of electrolyte and electrode as well as the change in current following on from the addition of, first, frozen and, second, boiling KOH aqueous solution (0.1 M). Quite surprisingly, only the addition of frozen KOH aqueous solution has a significant impact on current (+130%), caused by the decrease in electrolyte temperature (-11 degrees C). In contrast, the addition of boiling KOH aqueous solution has a negligible effect on current. A very similar behavior is recorded when frozen or boiling type III deionized water is used: the addition of ice has an even stronger impact on current (+145 %) and on electrolyte temperature (-14 degrees C), while adding boiling water has no measurable effect. Thus, we here demonstrated that electrolyte temperature is critical for managing the responsiveness of the CGDE system. Our results pave the way toward temperature controlled CGDE, a powerful tool for a greener and a more efficient environmental chemistry
Psychoanalytische Perspektiven. Ein Lesebuch. Wolfgang Schmidtbauer als Festschrift zum 60. Geburtstag
No full textBauer A, Gröning K, Grohs-Schulz M, eds. Psychoanalytische Perspektiven. Ein Lesebuch. Wolfgang Schmidtbauer als Festschrift zum 60. Geburtstag. Frankfurt a.M.: Lang; 2002
Lethe sisii Lang & Monastyrskii, sp. nov.
No full textLethe sisii Lang & Monastyrskii sp. nov. (Figs: 7, 8, 17, 18, 25 c, 27) Lethe manzora [sic]: Chou, 1994. Monographia Rhopalocerorum Sinensium, vol. 1, p. 342, figs. 5 ♂ upperside/underside (Jiangxi). Lethe monilifera: Wang & Zhao, 2000. Lep. China 5, Satyridae, p. 52, figs. ♂(Sichuan Tianquan), ♂ (underside). Type material. Holotype ♂, CHINA: Sichuan, Ebian, Heizhugou, 1800–2000 m, 16.VII. 2014, leg. S-y. Lang (LSY); Paratypes: 13 ♂♂, same locality and habitats as holotype, 16–18.VII. 2014, legs. Yi Lang & S-y. Lang (LSY); 1 ♂, CHINA: Sichuan, Qingcheng-shan, 12.VII. 1991, leg. Hao Huang (HH); 1 ♂, CHINA: [Chongqing], ginfu [Nanchuan, Mt. Jifoshan], 1400 m, JUL 17 1932, leg. Wang (CMNH); 1 ♀, CHINA: ditto, 1600 m, JUL 31 1932, leg. Wang (CMNH); 1 ♀, CHINA: Chongqing, Simian-shan, Dawopu, 1000 m, 7.VII. 2015, leg. Si-yao Huang (HSY); 1 ♂, CHINA: Gansu, Kangxian, Qinghe, 1200 m, 30.VI. 2015, leg. Zi-hao Liu (LZH); 2 ♀♀, CHINA: Shaanxi, Fengxian, Xiaonan-gou, 1500 m, 3–4 VIII. 2015, leg. Si-yao Huang (HSY); 1 ♀, CHINA: Hubei, Wufeng, Houhe, VIII. 2013, leg. Hao Huang (HH). Description. ♂ Forewing length: 29.5–31 mm. Forewing strongly elongated towards the apex. Upperside: ground color greyish brown; forewing postdiscal band with the paler outer border vestigial; forewing yellow subapical spots in cells M 1 and M 2 present; forewing with a weak and slender orange marginal line; hindwing postdiscal spots with the yellowish iris narrower and separated from each other by veins. Underside: ground color pale brown with markings similar to those of L. manzorum; reddish fasciae and bars narrow. Male genitalia. (Figs: 17, 18, 25 c) Uncus: very long and strongly bent downwards. Gnathos: base normal in width, then gradually tapering towards the end; it is bent downwards near the base, and bent upwards near the apex. Valva: apical part elongated distally as a tongue-shaped lobe; apex more or less rounded; dorsal edge weakly humped in apical half; central part of ventral edge angular. ♀ Forewing length: 33–34 mm. Similar to male. Upperside: forewing postdiscal band with well visible outer yellowish border which is vestigial in male. Underside: the same as in male. Diagnosis. L. sisii may be distinguished from L. manzorum by the combination of the following characters: a) upper surface of forewing with paler outer markings of postdiscal band vestigial, but prominent in L. manzorum; b) upper surface of hindwing with series of yellow ringed submarginal slender spots separated from each other; these spots somewhat wider and confluent in L. manzorum; c) under surface of both wings with reddish fasciae and bars much narrower than in L. manzorum (e.g. width of hindwing postdiscal fasciae in space 3: 0.9 –1.0 mm in this new species, 1.5–1.6 mm in manzorum); d) uncus longer than that in L. manzorum; e) gnathos bent downwards near the base, whereas it is bent upwards in L. manzorum; f) apical part of valva much more elongated than that in L. manzorum. Etymology. The specific name sisii is named after Mr. Si Si from Chengdu, a good friend of the first author. Distribution. China (Sichuan, Chongqing, SE Gansu, S. Shaanxi, Hubei, Jiangxi).Published as part of Lang, Song-Yun & Monastyrskii, Alexander L., 2016, Description of two new species of the Lethe manzorum - group (Lepidoptera, Nymphalidae, Satyrinae) from China, pp. 453-462 in Zootaxa 4103 (5) on pages 454-455, DOI: 10.11646/zootaxa.4103.5.3, http://zenodo.org/record/26487
Klinische Linguistik - Zur Behandlung neurogener Sprachstörungen
No full textHielscher-Fastabend M. Klinische Linguistik - Zur Behandlung neurogener Sprachstörungen. In: Knapp K, ed. Angewandte Linguistik. 3rd ed. Frankfurt: Lang Verlag; 2010: 526-543
Vanderbilt Center for Teaching: Episode 5 - James Lang on Teaching First-Year Students
No full textIncludes descriptive metadata provided by producer in MP3 file: "CFT Podcasting - Podcast Episodes - Episode 5 - James Lang on Teaching First-Year Students - In this episode, we feature an interview with James Lang, Associate Professor of English at Assumption College in Massachusetts. Dr. Lang is the author of Life on the Tenure Track: Lessons from the First Year, a memoir chronicling his first year as a faculty member, and On Course: A Week-by-Week Guide to Your First Semester of College Teaching. He also writes "On Course," a column on teaching that appears in the Chronicle of Higher Education. In the interview, Dr. Lang discusses the idea that undergraduate students can experience some kind of personal transformation during their first year of college. Is transformation a reasonable goal for first-year students? If not, what is a reasonable goal? What are some conditions that facilitate these types of goals? What are conditions that inhibit them?" Lang argues that self-awareness of core values is a more realistic goal. Classroom discussions rather than lectures promote self-examination.Peabody College of Education and Human Developmen
Streaming Coreset Constructions for M-Estimators
No full textWe introduce a new method of maintaining a (k,epsilon)-coreset for clustering M-estimators over insertion-only streams. Let (P,w) be a weighted set (where w : P - > [0,infty) is the weight function) of points in a rho-metric space (meaning a set X equipped with a positive-semidefinite symmetric function D such that D(x,z) <=rho(D(x,y) + D(y,z)) for all x,y,z in X). For any set of points C, we define COST(P,w,C) = sum_{p in P} w(p) min_{c in C} D(p,c). A (k,epsilon)-coreset for (P,w) is a weighted set (Q,v) such that for every set C of k points, (1-epsilon)COST(P,w,C) <= COST(Q,v,C) <= (1+epsilon)COST(P,w,C). Essentially, the coreset (Q,v) can be used in place of (P,w) for all operations concerning the COST function. Coresets, as a method of data reduction, are used to solve fundamental problems in machine learning of streaming and distributed data.
M-estimators are functions D(x,y) that can be written as psi(d(x,y)) where ({X}, d) is a true metric (i.e. 1-metric) space. Special cases of M-estimators include the well-known k-median (psi(x) =x) and k-means (psi(x) = x^2) functions. Our technique takes an existing offline construction for an M-estimator coreset and converts it into the streaming setting, where n data points arrive sequentially. To our knowledge, this is the first streaming construction for any M-estimator that does not rely on the merge-and-reduce tree. For example, our coreset for streaming metric k-means uses O(epsilon^{-2} k log k log n) points of storage. The previous state-of-the-art required storing at least O(epsilon^{-2} k log k log^{4} n) points
Efficiency and Loss Mapping of AC Motors using Advanced Testing Tools
No full textThe efficiency and loss maps represent an important tool to evaluate an electrical motor drive. The efficiency maps are usually computed using finite element analysis or equivalent circuits that take into account the motor losses. However, these methods need to be compared with efficiency maps that must be experimentally obtained using calibrated instruments. The main problem is how to implement an automated procedure that must obtain the motor or drive efficiency for all operating points. This paper describes an efficiency and loss mapping procedure that has been applied for a 5.3 kW three-phase internal permanent magnet machine prototype for traction applications, but it can be used for any AC machine with inverter supply. All measurements have been performed with an advanced data recorder instrument. The efficiency and loss maps are calculated after the test with a post-processing procedure that can provide all information regarding the motor exploitation, including current, voltage and flux vector trajectories in (d,q) rotor frame
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