2,928 research outputs found

    BHALLA-CLEENEWERCK JOURNAL EFFICIENCY FACTOR, BC-JEF©-A NOVEL AUTHOR-CENTRIC METRIC FOR JOURNAL EFFICIENCY

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    According to English definition, “efficiency” is the state or the quality of being able to accomplish something with the least waste of time and effort. Concerning the Journals, “efficiency” signifies providing the submitting authors with a peer-review decision with a least loss of time and academic value. The “efficiency”, on the journal’s part, also means least delays in academic returns that submitting authors deserve from their own work. The “efficiency”, on the journal’s part, also implies least delays in making available the access to possible benefits to the patients or public from the author’s work. In other words, efficiency is a measurable ability of the journals, whether paid or unpaid, to do their “duties well”, “efficiently”, “successfully”, and “without waste and avoidable loss” to the submitting authors. It is our vision to make the entire publication process coherent and convenient. At the same time, it is also our vision to guard the rights of submitting authors in having a time-bound, convenient, and efficient service with high customer service values from their service providers, i.e. the journals, whether paid or unpaid. For this, we introduce “Bhalla-Cleenewerck Journal Efficiency Factor (BC-JEF©)”, named in short as JEF©, as a parameter for assessing the functional efficiency of the journals. We introduce JEF©, an innovative non-profit measure to ensure the “greater good” of all concerned. For the journals, JEF© would help them recognize their duties and obligations for providing an efficient publication service to the authors. Also, JEF© would facilitate the journals in making their publication process more fulfilling and coherent, particularly for the authors, based on whom they thrive. JEF© would also help the journals in their healthy commercial competition. For the authors, JEF© would help them make an informed choice while submitting their work to a journal. For other agencies, JEF© provides them with an alternative metric to track parameters that are not being covered by any of the current existing journal metrics. Full text fully formatted PDF text version and Speech Abstract©: academia and Egnyte and [email protected] information: The Intergovernmental Research and Policy Journal (IRPJ) is a unique interdisciplinary peer-reviewed and open access Journal. It operates under the authority of the only global and treaty-based intergovernmental university in the world (EUCLID), with other intergovernmental organizations in mind. Currently, there are more than 17,000 universities globally, but less than 15 are multilateral institutions, EUCLID, as IRPJ's sponsor, is the only global and multi-disciplinary UN-registered treaty-based institution. IRPJ authors can be assured that their research will be widely visible on account of the trusted Internet visibility of its ".int" domain which virtually guarantees first page results on matching keywords (.int domains are only assigned by IANA to vetted treaty-based organizations and are recognized as trusted authorities by search engines). In addition to its ".int" domain, IRPJ is published under an approved ISSN for intergovernmental organizations ("international publisher") status (also used by United Nations, World Bank, European Space Agency, etc.). IRPJ offers: United Nations Treaty reference on your published article (PDF) "Efficiency" driven and "author-focused" workflow Operates the very unique author-centric metric of "Journal Efficiency Factor" Minimal processing fee with the possibility of waiver Dedicated editors to work with graduate and doctoral students Continuous publication i.e., publication of articles immediately upon acceptance The expected time frame from submission to publication is up to 40 calendar days Broad thematic categories Every published article will receive a DOI from Crossref and is archived by CLOCKSS. Submit manuscript: [email protected] EICs: Prof. Charalee GRAYDON, JD; Prof. Devender BHALLA, HDR Full text fully formatted PDF text version and Speech Abstract©: academia and Egnyte and [email protected] All copyrights remain with the author(s) and IRPJ. Cite as: Bhalla, D; Cleenewerck, L. Bhalla-Cleenewerck Journal Efficiency Factor (BC-JEF©)-A novel author centric metric for Journal efficiency. Intergovernmental Res Pol J (UN treaty). Vol. 2020, Issue e20, DOI: https://doi.org/10.36964/irpj2355, Article ID: 201, pages 1-5

    Studies on the development of instant `Dahi Bhalla' - an Indian traditional snack preparation.

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    Dahi bhalla is a traditional Indian deep fat fried savoury snack food. In this study, standardization of recipe, method of preparation, drying, packaging and storage of dahi bhalla were investigated. Dahi bhalla is conventionally made from a paste (peethi) of water soaked urd dhal (dehusked split black gram; Phaseolus mungo) in admixture with besan (dehusked split Bengal gram flour; Cicer arietinum) and spices. Alternatively, peethi can also be prepared from black gram flour by adding an equal amount of water to it. Addition of besan to peethi at 5% and sodium bicarbonate at 0.25% was optimum to yield the best quality product. To make instant dahi bhalla, the fried product was dried in a through-flow drier at 68-70°C, packed in a 150 gauge polypropylene pouch and stored at room temp. (15-25°C). The product kept for up to 12 wk. Dried dahi bhalla was soaked in hot water (60°C) for 20 min prior to use. Quality of dahi bhalla prepared from black gram flour was found to be comparable with that of dahi bhalla prepared form water-soaked dehusked, split black gram

    [GaF3(BzMe2-tacn)] – a neutral ‘metalloligand’ towards alkali metal and ammonium cations in water

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    The neutral complex, [GaF3(L)] (L = 1-benzyl-4,7-dimethyl-1,4,7-triazacyclononane, BzMe2-tacn), acts as a ‘metalloligand’ to Na+, K+ and [NH4]+ cations in aqueous solution, forming supramolecular assemblies containing significant Na/K–F and H3N+H⋯F coordination. κ1-[BF4]− and κ2-[PF6]− coordination is also evident to Na+ and K+, respectively

    A EMOTION-FOCUSSED TREATMENT FOR DECREASING CONJUGAL STRESS- A RANDOMIZED REPRESENTATIVE SINGLE-SITE CONTROLLED STUDY

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    Objective: Marital life is closely related to physical, social, and mental well-being. The aim of this study was to determine the reduction in chronic marital life stress among exposed subjects through the emotion re-focus approach. Methods: The individuals meeting our inclusion criteria were screened with the help of Stockholm Marital Stress Scale. The cognitive assessment was also made with the help of an Abbreviated Mental Test. The subjects were assigned a random number in a double-blind and independent manner, and half of them were provided eight therapeutic sessions lasting 90 minutes for eight weeks. The remaining ones were provided identical service after the entire data collection. All analyses were carried-out in 99.0% confidence interval, 0.01% type-I error and 1.0% type-II error. Results: A total of 138 subjects with marital life stress were allocated to both testing and control group. Both groups did not differ in social, statistical, and clinical variables. The between-group mean stress score did not differ statistically at baseline (p=0.1), but did differ at the culmination (p<0.001). For control group, the mean stress score changed from 2.8, 99%CI 2.7-2.9 to 2.7, 99%CI 2.6-2.8, p=0.1 between pre-post assessment. For testing group, the mean stress score changed from 2.9, 99%CI 2.8-3.0 to 2.4, 99%CI 2.3-2.5, p<0.001 (diff=17.2%, ES=1.40, R2=0.32) between pre-post assessment. The within-group improvement in stress score among subjects from their own baseline was 0-3.8% among control group and 1.9-30.6% in testing group. The sample power was 99.1%. Conclusions: Within our strengths and limitations, we may conclude that emotion re-focus may help to overcome chronic conjugal life distress with 0.1% false positive error. Full text fully formatted PDF text version and Speech Abstract©: academia and Egnyte and [email protected] information: The Intergovernmental Research and Policy Journal (IRPJ) is a unique interdisciplinary peer-reviewed and open access Journal. It operates under the authority of the only global and treaty-based intergovernmental university in the world (EUCLID), with other intergovernmental organizations in mind. Currently, there are more than 17,000 universities globally, but less than 15 are multilateral institutions, EUCLID, as IRPJ's sponsor, is the only global and multi-disciplinary UN-registered treaty-based institution. IRPJ authors can be assured that their research will be widely visible on account of the trusted Internet visibility of its ".int" domain which virtually guarantees first page results on matching keywords (.int domains are only assigned by IANA to vetted treaty-based organizations and are recognized as trusted authorities by search engines). In addition to its ".int" domain, IRPJ is published under an approved ISSN for intergovernmental organizations ("international publisher") status (also used by United Nations, World Bank, European Space Agency, etc.). IRPJ offers: 1. United Nations Treaty reference on your published article (PDF) 2. "Efficiency" driven and "author-focused" workflow 3. Operates the very unique author-centric metric of "Journal Efficiency Factor" 4. Minimal processing fee with the possibility of waiver 5. Dedicated editors to work with graduate and doctoral students 6. Continuous publication i.e., publication of articles immediately upon acceptance 7. The expected time frame from submission to publication is up to 40 calendar days 8. Broad thematic categories 9. Every published article will receive a DOI from Crossref and is archived by CLOCKSS. Submit manuscript: [email protected] EICs: Prof. Charalee GRAYDON, JD; Prof. Devender BHALLA, HD

    Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state

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    Alzheimer’s disease (AD) is characterized by the loss of memory due to aggregation of misphosphorylated tau and amyloid beta (Aβ) plaques in the brain, elevated release of inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and reactive oxygen species from astrocytes, and subsequent neurodegeneration. Recently, it was found that enzyme Ornithine Decarboxylase 1 (ODC1) acts as a bridge between the astrocytic urea cycle and the putrescine-to-GABA conversion pathway in the brain of AD mouse models as well as human patients. In this study, we show that the long-term knockdown of astrocytic Odc1 in APP/PS1 animals was sufficient to completely clear Aβ plaques in the hippocampus while simultaneously switching the astrocytes from a detrimental reactive state to a regenerative active state, characterized by proBDNF expression. Our experiments also reveal an effect of astrocytic ODC1 inhibition on the expression of genes involved in synapse pruning and organization, histone modification, apoptotic signaling and protein processing. These genes are previously known to be associated with astrocytic activation and together create a neuroregeneration-supportive environment in the brain. By inhibiting ODC1 for a long period of 3 months in AD mice, we demonstrate that the beneficial amyloid-clearing process of astrocytes can be completely segregated from the systemically harmful astrocytic response to insult. Our study reports an almost complete clearance of Aβ plaques by controlling an endogenous degradation process, which also modifies the astrocytic state to create a regeneration-supportive environment in the brain. These findings present the potential of modulating astrocytic clearance of Aβ as a powerful therapeutic strategy against AD. © 2024, The Author(s).11Ysciescopu

    Positional cloning identifies a candidate gene for mental retardation and epilespsy / by Kavita Bhalla.

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    Includes errata attached to inside front cover and first leaf.Includes a list of publications co-authored by the author during the preparation of this thesis.Includes bibliographical references (leaves 269-285).ix, 285 leaves : ill. (some col.) ; 30 cm."The work presented in this thesis provides the basis for further work to determine if A2BP1 is involved in sporadic autosomal mental retardation and/or epilepsy. Such studies are currently underway in the Department of Cytogenetics and Molecular Genetics, WCH, Adelaide. Identification of the gene related to mental retardation and/or epilepsy will further help in better understanding of the molecular basis of neuronal mechanisms underlying these disorders."Thesis (Ph.D.)--Adelaide University, Dept. of Paediatrics, 200

    J. S. Sharma, V. P. Gandhi, Production and Consumption of Foodgrains in India : Implications of Accelerated Economic Growth and Poverty Alleviation, report n° 81 G. S. Bhalla, G. K. Chadha, S. P. Kashyap, R. K. Sharma, Agricultural Growth and Structural Changes in the Punjab Economy : an Input-Output Analysis

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    Étienne Gilbert. J. S. Sharma, V. P. Gandhi, Production and Consumption of Foodgrains in India : Implications of Accelerated Economic Growth and Poverty Alleviation, report n° 81 G. S. Bhalla, G. K. Chadha, S. P. Kashyap, R. K. Sharma, Agricultural Growth and Structural Changes in the Punjab Economy : an Input-Output Analysis. In: Tiers-Monde, tome 32, n°127, 1991. « Investissement-travail » et développement. Des approches et pratiques renouvelées ? sous la direction de André Guichaoua. pp. 718-719
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