3,987 research outputs found
Explicit MSR Codes with Optimal Access, Optimal Sub-Packetization and Small Field Size for d = k+1, k+2, k+3
No full textThis paper presents the construction of an explicit, optimal-access, high-rate MSR code for any (n, k, d = k + 1, k + 2, k + 3) parameters over the finite field F-Q having sub-packetization alpha = q(inverted right perpendicular)n/q(inverted left perpendicular), where q = d - k + 1 and Q = O(n). The sub-packetization of the current construction meets the lower bound proven in a recent work by Balaji et al. in 1]. To our understanding the codes presented in this paper are the first explicit constructions of MSR codes with d < (n - 1) having optimal sub-packetization, optimal access and small field size
2022 IEEE Long Island Systems, Applications and Technology Conference (LISAT 2022)
No full textUma Balaji (with Patrick Evans, Ryan Avery, Maxwell Malcy, and Maverick Ruiz) is a contributing author, Multipurpose Solar Charging Station.https://digitalcommons.fairfield.edu/engineering-books/1079/thumbnail.jp
Knowledge Organization Systems for Semantic Digital Libraries
No full textAs the traditional knowledge organization systems (KOS)
like classification, thesauri are paving way for ontologies, transtechnological data models and semantic networks of data exchange
provide impetus for developing semantic digital libraries. This paper
attempts to find the KOS in the early digital libraries, and how they
can be integrated with the digital library architectures using emergent
semantic technologies and data. Metadata remains as a core area at the heart of the Semantic Web and realizing semantics on machines is the challenging task of Web services development. Knowledge representation and organization systems explore nature of metadata and their semantic relationships. This new-breed of social and semantic technologies and their potentialities, approaches for organizing the knowledge on the Web and their enjoining with digital libraries in the light of evolving Semantic Web is highlighted
On complete reducibility in characteristic
No full textLet be a reductive group over a field which is algebraically closedof characteristic . We prove a structure theorem for a class ofsubgroup schemes of , for bounded below by the Coxeter number of . Asapplications, we derive semi-simplicity results, generalizing earlier resultsof Serre proven in 1998, and also obtain an analogue of Luna's \'etale slicetheorem for suitable bounds on .Comment: Appendix is by Zhiwei Yu
Proceedings of the International Conference on Computers Communication and Devices, (ICCCD, 2000)
No full textUma Balaji is a contributing author, Computer aided design of e-plane diplexer.
Book description:
Papers presented at the International Conference on Computers Communication and Devices, (ICCCD, 2000), Indian Institute of Technology, Kharagpur, Dec 2000.https://digitalcommons.fairfield.edu/engineering-books/1035/thumbnail.jp
Aerosolizable Drug-Loaded SPIONs for Treatment and Diagnosis of Pulmonary Tuberculosis
No full text2025Tuberculosis (TB) remains one of the most pressing global infectious diseases, with the rise of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains presenting significant challenges to current therapeutic strategies. Existing treatment regimens are prolonged, systemically toxic, and poorly targeted, often resulting in poor patient compliance and limited drug penetration into granulomatous lesions in the lungs. To address these limitations, this study aimed to develop a pulmonary theranostic platform composed of poly(lactic-co-glycolic acid)-polyethylene glycol (PLGA-PEG) coated superparamagnetic iron oxide nanoparticles (SPIONs), capable of delivering antitubercular agents directly to the site of infection while providing T2-weighted magnetic resonance imaging (MRI) contrast for diagnostic tracking.SPIONs were synthesized via the chemical co-precipitation method and surface-stabilized with oleic acid to ensure colloidal stability. These SPIONs were subsequently encapsulated within PLGA-PEG matrices using an emulsion solvent evaporation method, with Ethambutol and a novel MmpL3 inhibitor, N-(adamantyl)-1H-indole-2-carboxamide (N2), incorporated as model therapeutic agents. The resulting nanoparticles were characterized by dynamic light scattering (DLS), transmission electron microscopy (TEM), powder X-ray diffraction (PXRD), and thermogravimetric analysis (TGA).
Optimized nanoparticles showed uniform spherical morphology with a hydrodynamic diameter of ~250 nm and high colloidal stability. LC-MS/MS confirmed efficient drug loading and encapsulation. T2 relaxivity studies demonstrated strong MRI contrast potential (r₂ = 73.709 s⁻¹·mM⁻¹; r₂/r₁ = 76.3), and magnetic analysis indicated superparamagnetic behavior with a blocking temperature near 50 K. Freeze-drying with cryoprotectants produced inhalable dry powders with MMADs of 2–4 µm, suitable for alveolar delivery. Cytotoxicity assays in A549 and BEAS-2B cells confirmed biocompatibility over 72 hours. The nanoparticles' extracellular antibacterial activity, coupled with their efficient uptake by macrophages, confirms that nanotechnology-enabled delivery can simultaneously enhance the safety, efficacy, and targeting of anti-tubercular therapies.
This study successfully developed a multifunctional, aerosolizable nanoparticle system for targeted pulmonary delivery of antitubercular drugs. The integration of SPIONs enables simultaneous therapeutic and diagnostic capabilities, supporting real-time treatment monitoring via MRI. The PLGA-PEG-coated SPIONs demonstrated high stability, a high drug loading capacity, efficient lung deposition, and strong antibacterial and imaging potential. This platform holds significant promise for improving TB therapy through enhanced lung-targeting, reduced systemic toxicity, and non-invasive monitoring of treatment efficacy
Innovative Techniques in Instruction Technology, E-learning, E-assessment, and Education
No full textUma Balaji is a contributing author, Demonstrations of Transmission Line Effects.
Book description:
Innovative Techniques in Instruction Technology, E-Learning, E-Assessment and Education is a collection of world-class paper articles addressing the following topics:
E-Learning including development of courses and systems for technical and liberal studies programs; online laboratories; intelligent testing using fuzzy logic; evaluation of on line courses in comparison to traditional courses; mediation in virtual environments; and methods for speaker verification.
Instruction Technology including internet textbooks; pedagogy-oriented markup languages; graphic design possibilities; open source classroom management software; automatic email response systems; tablet-pcs; personalization using web mining technology; intelligent digital chalkboards; virtual room concepts for cooperative scientific work; and network technologies, management, and architecture.
Science and Engineering Research Assessment Methods including assessment of K-12 and university level programs; adaptive assessments; auto assessments; assessment of virtual environments and e-learning.
Engineering and Technical Education including cap stone and case study course design; virtual laboratories; bioinformatics; robotics; metallurgy; building information modeling; statistical mechanics; thermodynamics; information technology; occupational stress and stress prevention; web enhanced courses; and promoting engineering careers.
Pedagogy including benchmarking; group-learning; active learning; teaching of multiple subjects together; ontology; and knowledge representation.
Issues in K-12 Education including 3D virtual learning environment for children; e-learning tools for children; game playing and systems thinking; and tools to learn how to write foreign languages.https://digitalcommons.fairfield.edu/engineering-books/1034/thumbnail.jp
FIGURE 10. First gill arch, A in Barilius ardens (Teleostei: Cyprinidae), a new species from the Western Ghats, India, with redescription of B. malabaricus and B. canarensis
No full textFIGURE 10. First gill arch, A, Barilius bakeri, MKC 384, 68.7 mm SL; B, B. canarensis, MKC 415, 63.4 mm SL (Scale bar = 2 mm).Published as part of Marcus Knight, J. D., Rai, Ashwin, D'Souza, Ld. K. P. & Vijaykrishnan, Balaji, 2015, Barilius ardens (Teleostei: Cyprinidae), a new species from the Western Ghats, India, with redescription of B. malabaricus and B. canarensis, pp. 396-412 in Zootaxa 3926 (3) on page 407, DOI: 10.11646/zootaxa.3926.3.5, http://zenodo.org/record/24289
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