293 research outputs found
New Roles for Librarian of Bosscha Observatory
Mr. K. A. R Bosscha, a Dutch tea planter and successful businessman, has become a legendary figure in Indonesia for his various concerns to the society: mostly in public health, education, and science. Through his generous support, he materialized the foundation of a modern astronomical observatory in the tropics in 1920, namely Bosscha Observatory. The site of the observatory was partially donated by Mr. Ursone, an Italian businessman, and is located in Lembang, West Java, which was a good and suitable place for southern hemisphere observation.
In the directorship of Dr. Voute, Prof. H.G.van de Sande Bakhuijzen, retired Director of Leiden Observatory, donated his collection of books and journals on astronomy which become the core of the Bosscha Observatory library.The library of Bosscha Observatory was built to support and facilitate research activities of the Indonesian astronomers.
Results of research and references on astronomy from time to time are kept and managed following the development of astronomy itself and related science and technology. Institut Teknologi Bandung (ITB), The Leids Kerkhoven Bosscha Foundation (LKBF), and various national and international institutions have contributed to the development of the library. Today, information technology development is adopted as well in Bosscha Observatory and shapes new roles for librarian
SLN biopsy indications and controversies in breast cancer.
Contains fulltext :
127355.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 27 juni 2014Promotor : Wilt, J.H.W. de Co-promotor : Bosscha, K
Pelvic sepsis after stapled hemorrhoidopexy
Bosscha K contributed equally to this work; van Wensen RJA did the literature research and wrote the manuscript under the supervision of van Leuken MH and Bosscha K
A fossil reduncine antelope from the locality K 2 East of Maragheh, N. W. Iran
Volume: 22Start Page: 103End Page: 11
Surgical and epidemiological aspects in gastric cancer patients. The role of age, centralization and palliative treatment
Internal fixation of metacarpal and phalangeal fractures with AO minifragment screws and plates: a prospective study
Intraoperative fluorescence imaging : clinical translation of targeted and non-targeted tracers
Surgery is the cornerstone of curative treatment of many malignancies. However, incomplete resections and avoidable iatrogenic damage during surgery increase morbidity and mortality rates in patients. Although advances in preoperative imaging modalities have improved adequate patient selection and surgical planning, during procedures surgeons rely mainly on inspection and palpation. It is often very difficult to distinguish between fibrotic, inflamed, or malignant tissues [1]. Inspection and palpation are highly subjective and have low sensitivity for detecting cancer, especially for subcentimeter lesions [2].Near-infrared fluorescence (NIRF) imaging is a technique that enhances contrast of certain structures during surgery and thereby improves their detectability [3, 4]. It uses targeted and non-targeted fluorescent tracers in combination with dedicated NIRF imaging systems. These tracers consist of fluorophores; molecules that emit fluorescence with a certain wavelength upon excitation by an external light source. These fluorescence signals can be captured by an imaging system optimized for that specific wavelength. Especially near-infrared wavelengths (i.e. 700-900 nm) have excellent characteristics, including relatively high tissue penetration capacity and low tissue autofluorescence, and are therefore preferably used for clinical applications [5]. NIRF imaging can identify targets covered by up to 10 mm tissue.Non-targeted fluorescent tracers such as indocyanine green (ICG; emission peak 830 nm) and methylene blue (emission peak 700 nm) have been available for several decades, albeit for different indications. Their off-label use is safe and cheap, which contributed significantly to clinical experience and enabled NIRF imaging research to get momentum (chapter 2 and 3). NIRF imaging systems could be developed simultaneously with improved fluorophores. In general, NIRF-guided surgery has the potential to increase radical resection rates, while reducing avoidable iatrogenic damage. Both non-targeted as well as targeted tracers will be discussed, followed by the future perspectives of NIRF imaging.Non-specificLUMC / Geneeskund
Prognosis and Survival in patients with Colorectal Cancer
The aim of this thesis was to investigate the outcome after colorectal surgery and to try to find possible ways to improve staging and treatment, especially in patients with stage I and II colonic cancer. The first part of this thesis describes the outcome and quality of life in patients with colorectal cancer. Chapter 2 evaluated long-term survival in patients who underwent pulmonary resection for metastases of colorectal cancer. Patients with untreated metastatic disease have a median survival of less than 10 months and a 5-year survival of less than 5%.In a highly selected group of patients surgical intervention is the therapy of choice. In our series, the actuarial 5-year survival was 25%, and the disease-free survival was 18%. The two-year overall survival for patients with solitary lesions was 70% against 50% for patients with multiple lesions. In Chapter 3 we investigated the outcome of surgery in elderly patients (>75 years) with colon cancer in order to determine the best treatment strategy. In our series, the five-year survival rate of patients treated with curative resection was 62% in the younger group
Regression of Martian North polar cap 1994-1995
The regression of the Martian north polar cap during the 1994-1995 apparition is examined with the measurements of the CCD (Charge Coupled Device) images and of the photographs of Mars obtained at the Hida Observatory, at the Vainu Bappu Observatory, and at the Bosscha Observatory. The retreat of the cap stopped until Mars reached about Ls = 54 deg (Ls is the areocentric longitude of the sun) when the cap started to shrink. The regression of the north polar cap in 1994-1995 appears to have been a little faster than the mean regression or the regression in 1979-1980, but to have been similar to those in 1946, in 1948, in 1950, in 1972, and in 1977-1978. Like the case of the south polar cap, the behavior of the north polar cap seems to be different from year to year
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